Generic Name: Zovirax
What is Zovirax?
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Zovirax Cold Sore CreamPromotes healingAnti-Viral treatmentAge RestrictionYou must be at least 16 years old to purchase this product. Please read the enclosed leaflet carefully before use. Adults and children: Apply the cream liberally to completely cover the whole of the affected area.
Apply to the affected area five times a day at approximately 4 hourly intervals for four days. Consult your doctor or pharmacist before using this product if you know that your immune system is weakened.
The inhibitory activity of Aciclovir for HSV I and HSV II and VZV is highly selective. Aciclovir triphosphate interferes with the viral DNA polymerase and inhibits viral DNA replication with resultant chain termination following its incorporation into the viral DNA.
Prolonged or repeated courses of Aciclovir in severely immuno-compromised individuals may result in the selection of virus strains with reduced sensitivity, which may not respond to continued Aciclovir treatment. Most of the clinical isolates with reduced sensitivity have been relatively deficient in viral TK, however, strains with altered viral TK or viral DNA polymerase have also been reported.
In vitro exposure of HSV isolates to Aciclovir can also lead to the emergence of less sensitive strains. The relationship between the in vitro-determined sensitivity of HSV isolates and clinical response to Aciclovir therapy is not clear. Mean steady state peak plasma concentrations Cssmax following doses of 800 mg Aciclovir administered four-hourly were 8 microMol 1. In adults the terminal plasma half-life after administration of intravenous Aciclovir is about 2.
Most of the drug is excreted unchanged by the kidney. Renal clearance of Aciclovir is substantially greater than creatinine clearance, indicating that tubular secretion, in addition to glomerular filtration, contributes to the renal elimination of the drug. Carcinogenicity:- Aciclovir was not found to be carcinogenic in long term studies in the rat and the mouse. Teratogenicity:- Systemic administration of aciclovir in internationally accepted standard tests did not produce embryotoxic or teratogenic effects in rats, rabbits or mice.
Fertility:- Largely reversible adverse effects on spermatogenesis in association with overall toxicity in rats and dogs have been reported only at doses of aciclovir greatly in excess of those employed therapeutically. Name of the medicinal product Aciclovir 800mg BPFor the full list of excipients, see section 6.
How should I take Zovirax?
Do not give ZOVIRAX Cream to other people, even if they have the same symptoms you have. It may harm them. You can ask your pharmacist or healthcare provider for information about ZOVIRAX Cream that is written for health professionals. What are the ingredients in ZOVIRAX Cream. For adolescents 12 years of age and older, the dosage is the same as in adults. The safety profile in patients 12 to 17 years of age was similar to that observed in adults.
What should I avoid while taking Zovirax?
Having said that, he said the companies are just covering themselves because its only a topical application, you are not swallowing large amounts of it, so the chances of the minimal amount getting into your system and actually affecting the baby are nil.
He himself had never heard of any baby suffering ill effects as a result of the mother using it. He said I would be fine to use it from week 13 or so on.
MiriamI had a pretty bad viral eye infection last year when I was sixteen weeks pregnant with my daughter. I went to my GP, showed him the creams, he said they were for bacterial infections and not viral and said that he felt the only thing that would work was Zovirax eye cream, but firstly he rang the MDU to double check if it was safe to use. They said yes and heh presto, within three applications there was a major improvement, so I would think, but again you should check, even ring the MDU yourself, that Zovirax for cold sores is safe.
Dont worry at all. You are applying a tiny amount topically.
Zovirax side effects
Lori Mendoza, PharmDA: Acyclovir Zovirax is an antiviral medication indicated for the acute treatment of herpes zoster shinglesthe treatment of initial episodes and the management of recurrent episodes of genital herpes and the treatment of chickenpox.
Acyclovir is only approved, by the U. Food and Drug Administration FDAfor the treatment of chickenpox in the pediatric population 2 year of age and older. The safety and effectiveness of oral acyclovir in the pediatric population, younger than 2 years of age, has not been established. The dosage and administration of oral acyclovir depends upon the indication for use and age of the patient.
Acyclovir can be administered with or without food. Acyclovir is the generic equivalent of Zovirax and is currently available, for oral administration, in capsule and tablet form and as a suspension for patients who have difficulty swallowing pills. Treatment with acyclovir should be initiated as soon as possible after the first appearance of symptoms, such as tingling, burning or blisters.
Common Zovirax ide effects may include:
However, all values for these parameters remained within limits accepted as normal.
Cold sore sufferers should be advised to avoid transmitting the virus, particularly when active lesions are present.
It is essential for patients to consult a health care provider if they experience any unusual or bothersome adverse reactions while being treated with acyclovir for further evaluation.
Continue treatment for 5 days.
Where can I get more information?
The side effects listed above may not include all of the side effects reported by the medicine's manufacturer.
Bij virusinfecties zoals herpes genitalis een geslachtsziektegordelroos herpes-zoster-virus en koortslip herpes-simplex-virus.