Generic Name: Zofran

What is Zofran?

What is a systematic review. It is also used to prevent… Read more Brand names include: Zofran, Zofran ODT By injection Ondansetron injection is used to prevent the nausea and vomiting that may occur after treatment with cancer medicines chemotherapy or radiationincluding… Read more Brand names include: Amerinet Choice Ondansetron, BD Simplist Ondansetron Drug classes About this Antiemetic What works.

Comparing Newer AntiemeticsHow do newer antiemetics compare in in adults. Interventions for treating severe nausea and vomiting during pregnancy hyperemesis gravidarum Although severe nausea and vomiting in pregnancy hyperemesis gravidarum rarely causes death, it is an important cause of ill health with emotional, physical, and economic consequences.

See all 12 Things you need to know Approved drug uses More information about a drug Tips about using medicines PubMed Health Blog. Please review our privacy policy. For a full list of excipients see section 6. Pharmaceutical form Injection aqueous solution. Zofran is indicated for the prevention and treatment of post-operative nausea and vomiting PONV. The emetogenic potential of cancer treatment varies according to the doses and combinations of chemotherapy and radiotherapy regimens used.

The route of administration and dose of Zofran should be flexible in the range of 8-32 mg a day and selected as shown below.

Did you experience many side effects while taking this drug. How likely would you be to recommend Zofran to a friend. OverviewUsesBrand NamesDrug ClassSide EffectsDrug InteractionsDrug PrecautionsFood InteractionsInform MDPregnancyLactationDrug UsageDrug DosageOverdoseOther RequirementsZofran Drug ClassBack to TopZofran is part of the drug class:Serotonin 5HT3 antagonists Side Effects of ZofranBack to TopZofran can cause serious side effects.

See "Drug Precautions" section. Common side effects include:headachetirednessconstipationdiarrheadizzinessThis is not a complete list of Zofran side effects. Zofran PrecautionsBack to TopSerious side effects have been reported with Zofran including:hypotension.

Zofran and apomorphine Apokyn should not be taken at the same time as there is a risk of dangerously low blood pressure and loss of consciousness.

ECG changes including QT interval prolongation has been seen in patients receiving Zofran. Using Zofran after abdominal surgery or chemotherapy may mask the symptoms of an intestinal blockage abdominal ileus. Zofran Food InteractionsBack to TopMedications can interact with certain foods. Inform MDBack to TopBefore taking Zofran, tell your doctor about all of your medical conditions.

How should I take Zofran?

HOW SUPPLIED ZOFRAN Tablets, 4 mg ondansetron HCl dihydrate equivalent to 4 mg of ondansetronare white, oval, film-coated tablets engraved with "Zofran" on one side and "4" on the other in daily unit dose packs of 3 tablets NDC 0173-0446-04bottles of 30 tablets NDC 0173-0446-00and unit dose packs of 100 tablets NDC 0173-0446-02. Bottles:Store between 2and 30 36and 86Protect from light.

Dispense in tight, light-resistant container as defined in the USP. Unit Dose Packs: Store between 2and 30 36and 86Protect from light. Store blisters in cartons.

What should I avoid while taking Zofran?

Zofran and Zuplenz are prescription drugs used to treat nausea related to surgeries, cancer treatment and pregnancy.

The drug has been prescribed for off-label uses despite the fact that there is a risk of side effects like serotonin syndrome and pregnancy risks. Zuplenz is another formulation of ondansetron, manufactured by Galena Biopharma Inc. Food and Drug Administration FDA has not approved these drugs for this indication. These 5-HT3 receptors attract serotonin produced by the body in response to, for example, chemotherapy drugs. Other Zofran generic equivalent products have been approved by the FDA and have been available in the U.

The Zofran and Zuplenz package inserts contain several contraindications and warnings, summarized as follows:The package inserts that accompany Zofran and Zuplenz advises doctors to monitor patients for signs of serotonin syndrome.

Zofran side effects

My DH nearly died when he found out how expensive they are, then asked if I could somehow 'convince' myself to NOT vomit. I'll claim it all on tax, so hopefully I get a fair chunk back. TIA for any responses, much appreciated ipb.

Developed nearly two and half decades ago to help both cancer and surgery patients manage their heavy nausea and vomiting, Zofran has gained much attention and criticism recently over the birth defects and medical conditions linked to its usage.

When GlaxoSmithKline GSKa multi-billion dollar pharmaceutical company, first created the drug, there was no testing or approval given for the drug to be given to pregnant mothers.

However, less than 10 years ago, things began to change.

Common Zofran ide effects may include:

  • Cancer can be treated through chemotherapy, a treatment of drugs that destroy cancer cells.

  • Orally disintegrating solid All possible dosages and drug forms may not be included here.


  • Una singola dose maggiore di 16 mg non deve essere somministrata a causa dell'aumento del rischio dosedipendente di prolungamento dell'intervallo QT vedere Precauzioni per l'uso e Effetti indesiderati.

Serotonin Syndrome: Severe reactions are possible when ondansetron is combined with other medications that act on serotonin, such as tricyclic antidepressants and serotonin reuptake inhibitors, medications used to treat depression. These combinations must be avoided. This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately. Breast-feeding: It is not known if ondansetron passes into breast milk.

More about Zofran

Consumer resources

Other brands:Generic zithromax dispersible

Professional resources

Where can I get more information?

  • Novartis Pharmaceuticals UK LtdFrimley Business ParkFrimley CamberleySurrey GU16 7SR Date of first authorisation: 07 March 1990Date of latest renewal: 23 October 2001 Company contact details Novartis Pharmaceuticals UK Ltd novartis.

  • Chemotherapy and Radiotherapy induced nausea and vomiting.