Generic Name: Zithromax
What is Zithromax?
Take azithromycin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Shake the liquid well before each use to mix the medication evenly. Use a dosing spoon, oral syringe, or measuring cup to measure the correct amount of medication. Rinse the measuring device with water after taking the full dose of medication.
If you receive azithromycin powder for suspension in the single-dose, 1-gram packet, you must first mix it with water before you take the medication. Use the extended-release liquid within 12 hours of receiving it from the pharmacy or adding water to the powder. If you vomit within an hour after taking azithromycin, call your doctor right away.
Your doctor will tell you if you need to take another dose. Do not take another dose unless your doctor tells you to do so.
Liver toxicity caused by azithromycin has the potential to be severe and fatal incidents have been reported. Zithromax may also increase the risk of heart problems and resulting death in patients, a risk which was only uncovered in a study published in 2012, about two decades after the antibiotic was first put on the market.
The study was published in the New England Journal of Medicine and it found that people taking azithromycin were more likely to die of cardiovascular events than people taking another type of antibiotic or no antibiotic. From reports of adverse events sent to the FDA the researchers were able to figure out that Zithromax use led to irregular heartbeats.
The warning outlined the findings of the study. The results from the Pfizer study confirmed the risk, and the FDA issued a stronger warning in 2013.
This warning stated that azithromycin products have the potential to cause changes to the electrical activity of the heart, which could cause an irregular heartbeat that could be fatal in some patients. Pfizer updated its Zithromax labeling to include all the most recent information and warnings about the risk of irregular heart rhythms and the resulting risk of death for some patients. The company did this in response to the irrefutable evidence from researchers and the announcements and warnings from the FDA.
Although they responded to the evidence uncovered by research, it was a full two decades between when the drug was first made available to when the company communicated to the public that there was this fatal risk associated with it. Because of this long gap between years of use of the medication and public awareness of the risks, Zithromax users may have reason to sue Pfizer.
The loved ones of those who died of a cardiovascular event while taking the antibiotic may have the strongest cases. They may be able to make the case that Pfizer knew or should have known that this risk existed. If you have suffered because of Zithromax, talk to a lawyer about the options you have for taking action and seeking monetary compensation.
Uses for Zithromax Originally the FDA approved azithromycin for the treatment of acute bronchitis and sinusitis in adults as well as uncomplicated skin infections in adults.
How should I take Zithromax?
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What should I avoid while taking Zithromax?
Children over 45 kg body weight and adults, including elderly patients: The total dose of azithromycin is 1500 mg which should be given over three days 500 mg once daily. In uncomplicated genital infections due to Chlamydia trachomatis, the dose is 1000 mg as a single oral dose.
For susceptible Neisseria gonorrhoeae the recommended dose is 1000 mg or 2000 mg of azithromycin in combination with 250 mg or 500 mg ceftriaxone according to local clinical treatment guidelines. Paediatric population:In children under 45 kg body weight: Zithromax Capsules are not suitable for children under 45 kg.
Hepatic impairment:Since azithromycin is metabolised in the liver and excreted in the bile, the drug should not be given to patients suffering from severe liver disease. No studies have been conducted regarding treatment of such patients with azithromycin see section 4.
Zithromax side effects
Is this a real problem, or is it simply a retrospective study by a bunch of scientists wanting to make a splash. Tying this to the Zithromax study:And if you are able to access Table 1 of the paper, you will see that their propensity matching was spectacularly successful. So, although it does not eliminate the possibility that something unobserved or unmeasured is causing this increase in deaths, the meticulous methods used lower the probability of this.
So by this I am led to believe the data have some beef behind them. There were several studies in 1999 and 2000 in which azithromycin was given to patients with CAD in order to prevent secondary events.
Common Zithromax ide effects may include:
Children: The safety and efficacy of azithromycin tablets or suspension have not been established for treating children younger than 6 months of age who have acute otitis media or community-acquired pneumonia.
For more complicated disease such as acute sinusitis, doctors prescribe 500 mg a day for three days.
Fertility In fertility studies conducted in rats, reduced pregnancy rates were noted following administration of azithromycin.
Reconstitution Prepare the initial solution of ZITHROMAX for injection by adding 4.
Posology: Zithromax capsules should be given as a single daily dose. Paediatric population: In children under 45 kg body weight: Zithromax Capsules are not suitable for children under 45 kg. Hepatic impairment: Since azithromycin is metabolised in the liver and excreted in the bile, the drug should not be given to patients suffering from severe liver disease.
Where can I get more information?
Do not take antacids that contain aluminum or magnesium within 2 hours before or after you take Zithromax.
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