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It does not take the place of talking to your or your child's doctor or pharmacist. All medicines have risks and benefits.

Your doctor has weighed the risks of you or your child taking Zyvox against the expected benefits it will have. Ask the doctor if you have any concerns about you or your child taking this medicine.

What Zyvox is used for Zyvox contains the active ingredient, linezolid. Zyvox is an antibiotic an agent used to destroy certain types of bacteria. It is used in the treatment of bacterial infections such as pneumonia, skin infections or blood infections. Ask your doctor if you have any questions about why Zyvox has been prescribed for you or your child. Before taking Zyvox When you must not take it Do not take Zyvox or give Zyvox to your child before you talk to your doctor or pharmacist if you or your child:are allergic to linezolid or any of the other ingredients listed at the end of this leaflet.

Some of the symptoms of an allergic reaction may include: shortness of breath, wheezing or difficulty breathing, swelling of the face, lips, tongue or other parts of the body, rash, itching or hives on the skin. If you have any concerns about you or your child taking Zyvox speak to your doctor or pharmacist. If you are pregnant or breastfeeding, the doctor may decide not to prescribe Zyvox.

Talk to your doctor before using this form of linezolid if you have phenylketonuria PKU. Injectable linezolid is injected into a vein through an IV. Use the missed dose as soon as you remember. If you have diarrhea that is watery or bloody, stop taking linezolid and call your doctor. Avoid foods that have a high level of tyramine, such as:You should become very familiar with the list of foods you must avoid while you are using linezolid.

During your treatment with linezolid, do not start or stop using any other medications unless your doctor tells you to, especially: This list is not complete and many other drugs can interact with linezolid. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. For medical advice relating to your personal condition, please consult your doctor.

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After the study was completed, 13 additional patients ranging from 4 days through 16 years of age were enrolled in an open-label extension of the VRE arm of the study. Table 19 provides clinical cure rates by pathogen for microbiologically evaluable patients including microbiologically evaluable patients with vancomycin-resistant Enterococcus faecium from the extension of this study.

Clinical and Laboratory Standards Institute CLSI. Patients should be counseled that antibacterial drugs including ZYVOX should only be used to treat bacterial infections. They do not treat viral infections e.

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Prevention of MRSA Infection Hygiene is also key to the prevention of MRSA infection. The following is a list of medications which have been considered so dangerous by the medical profession that they have either been withdrawn from the market, or their use is restricted to only certain types of patients, or they are allowed to be used, but all information about the drug is required to contain warnings of the severe side effects that may result.

Even with strict labeling requirements, this has not been enough to prevent deaths and severe disability due to adverse reactions to these medications. What does one of the most respected medical journals in the country have to say about the risks of medications. Since its approval by the FDA 24 years earlier, it had been in widespread use - presumably, no one was aware of its very serious side effects.

Not much later, in December of 1997, the popular nonsedating antihistamine terfenadine Seldane was withdrawn due to its risk of causing potentially fatal heart arrhythmias when combined with the macrolide class of antibiotics and because safer alternatives existed. The drug had been in widespread use since its FDA approval 12 years previously.

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Antibiotic-associated diarrhoea and colitis Antibiotic-associated diarrhoea and antibiotic-associated colitis, including pseudomembranous colitis and Clostridium difficile-associated diarrhoea, has been reported in association with the use of nearly all antibiotics including linezolid and may range in severity from mild diarrhoea to fatal colitis. Lactic acidosis Lactic acidosis has been reported with the use of linezolid.

Mitochondrial dysfunction Linezolid inhibits mitochondrial protein synthesis. Serotonin syndrome Spontaneous reports of serotonin syndrome associated with the co-administration of linezolid and serotonergic agents, including antidepressants such as selective serotonin reuptake inhibitors SSRIs have been reported.

Convulsions Convulsions have been reported to occur in patients when treated with Zyvox.

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  • This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.

  • Code Definition PA Prior Authorization Drugs that require prior authorization.

  • Learn about hepatitis c symptoms, how you get hepatitis c, contagiousness, and hepatitis C treatment for this potentially fatal viral infection that affects the liver.

  • To kick things off, it is important to only administer Zyvox according to the prescription given by your doctor.

Zyvox BackgroundZyvox is an antibiotic medication used to treat different types of bacterial infections such as pneumonia, skin infections, and other infections that are resistant to antibiotics.

Zyvox Serotonin SyndromeZyvox-induced serotonin syndrome is a rare but potentially life threatening drug interaction that causes the body to have too much serotonin, a brain chemical produced by nerve cells. Signs and symptoms may include:agitation or restlessnessdiarrheafast heart beathallucinationsincreased body temperatureloss of coordinationnauseaoveractive reflexesrapid changes in blood pressurevomitingAccording to the Mayo Clinic, treatment of serotonin syndrome varies widely from patient to patient and depends largely on the severity of the symptoms.

Depending on your symptoms, you may receive one ore more of the following treatments:muscle relaxants - Benzodiazepines such as Valium or lorazepam can help control agitation, seizures and muscle stiffness. If you are taking ZyvoxUnder all but the most extreme circumstances, Zyvox should not be given to patients taking serotonergic medications.

Where can I get more information?

  • Elderly: The pharmacokinetics of linezolid are not significantly altered in elderly patients aged 65 and over.

  • Uncomplicated skin and skin structure infections caused by Staphylococcus aureus methicillin-susceptible only or Streptococcus pyogenes.