Generic Name: Ticlid
What is Ticlid?
How this information was developed to help you make better health decisions. Dan shen Salvia miltiorrhiza Dan shen, a Chinese herb, was associated with increased warfarin activity in two cases. Herbs containing coumarin-derivatives Although there are no specific studies demonstrating interactions with platelet inhibitors, the following herbs contain coumarin-like substances that may cause bleeding and therefore interact with ticlopidine.
Ticlopidine is an effective inhibitor of platelet aggregation. Ticlopidine is marketed under the brand name Ticlid and is indicated for patients who cannot take aspirin or in whom aspirin has not worked to prevent a thrombotic stroke. The FDA label includes a black-box warning of neutropenia, aplastic anemia, thrombotic thrombocytopenia purpura, and agranulocytosis, so it is necessary to monitor patients' WBC and platelets when they are taking ticlopidine. Used in patients, who have had a stroke or stroke precursors and who cannot take aspirin or aspirin has not worked, to try to prevent another thrombotic stroke.
How should I take Ticlid?
A drug that blocks platelet aggregation, C14H14ClNS, used in its hydrochloride form to prevent stroke and to treat intermittent claudication. Facebook Twitter My bookmarks.
Please log in or register to use bookmarks. References in periodicals archive. Clopidogrel: to test or not to test. Shock wave lithotripsy in patients requiring anticoagulation or antiplatelet agentsThese medicines include aspirin, clopidogrel Plavixdalteparin Fragminenoxaparin Lovenoxheparin, ticlopidine Ticlidwarfarin Coumadinand others. Air pollution-related prothrombotic changes in persons with diabetesMost 379 involved a risk of bleeding due to use of ginkgo, garlic or ginseng together with aspirin, warfarin, ticlopidine or pentoxifylline.
What should I avoid while taking Ticlid?
It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Controlled studies in pregnant women show no evidence of fetal risk.
Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C:Use with caution if benefits outweigh risks. View explanations for tiers and restrictions Tier Description 1 This drug is available at the lowest co-pay.
Ticlid side effects
Calcium Carbonate: Administration of ticlopidine after antacids results in a decrease in plasma levels of ticlopidine. Carbamazepine: Neurological toxicity and increased carbamazepine serum concentrations have been reported in a coronary stent patient treated with ticlopidine. This potential interaction requires further evaluation. Carisoprodol: Carisoprodol is extensively metabolized and is a significant substrate of CYP2C19 isoenzymes.
Chlorambucil: An additive risk of bleeding may occur when platelet inhibitors are used with agents that cause clinically significant thrombocytopenia including antineoplastic agents, such as chlorambucil. Although these effects have not been confirmed in published medical literature or during clinical studies, clinicians should consider using methylsulfonylmethane, MSM with caution in patients who are taking anticoagulants or antiplatelets including clopidogrel until data confirming the safety of these drug combinations are available.
During one of the available, published clinical trials in patients with osteoarthritis, those patients with bleeding disorders or using anticoagulants or antiplatelets were excluded from enrollment.
Common Ticlid ide effects may include:
This blocks the process of blood clot formation and reduces the risk of heart attack and stroke in those patients.
Ticlopidine is classified in FDA pregnancy risk category B.
Although this interaction has not been studied by the manufacturer, and published literature suggests the potential for interactions to be low, taking these drugs together may increase the systemic exposure of terbinafine.
Dan shen Salvia miltiorrhiza Dan shen, a Chinese herb, was associated with increased warfarin activity in two cases.
The risk or severity of adverse effects can be increased when Ticlopidine is combined with Ibritumomab tiuxetan. The serum concentration of the active metabolites of Ifosfamide can be reduced when Ifosfamide is used in combination with Ticlopidine resulting in a loss in efficacy.
The risk or severity of adverse effects can be increased when Limaprost is combined with Ticlopidine. The risk or severity of adverse effects can be increased when Ticlopidine is combined with Mesalazine.
Where can I get more information?
Use in Hepatically Impaired Patients: Since ticlopidine is metabolized by the liver, dosing of TICLID ticlopidine hcl or other drugs metabolized in the liver may require adjustment upon starting or stopping concomitant therapy.
Their mode of action has not been defined, but it appears that they require conversion to as yet unidentified metabolites that are noncompetitive antagonists of the platelet ADP receptor.