Generic Name: Symmetrel
What is Symmetrel?
If you are taking antipsychotic medicines you should not stop taking amantadine suddenly, as this can increase the risk of side effects from the antipsychotic medicine. The web site does not have answers to all problems. Answers to specific problems may not apply to everyone. If you notice medical symptoms or feel ill, you should consult your doctor - for further information see our Terms and conditions.
However in practice it is no longer used for this purpose because there are other more effective medicines now available. How does it work. Symmetrel capsules and syrup contain the active ingredient amantadine hydrochloride, which is a medicine used mainly in the treatment of Parkinson's disease. What if I forget a dose of pregabalin. Find out if it's OK to take other painkillers or drugs while you're taking pregabalin By Rita Ghelani Medication and elderly people Be informed.
This medicine is a red capsule imprinted with "GG 634 GG 634". This medicine is a red capsule imprinted with "652".
The loss of dopamine seen in Parkinson's disease is due to slow and progressive destruction of the neurons that produce the dopamine in a certain area of the brain called the substantia nigra.
Amantadine in Symmetrel 100 is thought to increase the amount of dopamine in the brain by enhancing the release of dopamine from central neurons and by delaying its re-uptake from the synapse, the gap between nerve cells across which chemical messages are sent from one nerve cell to another. The increase in dopamine levels helps the brain control muscle function and restore normal movement.
Amantadine in Symmetrel 100 is also thought to exert some anticholinergic activity, which means that it blocks the binding of the neurotransmitter acetylcholine to its receptor in nerve cells and this action helps prevent the involuntary movements associated with Parkinsonism. The mechanism of action by which Symmetrel 100 prevents the growth of influenza A virus is not known but it is thought to be due to interference with a viral protein needed for the virus to infect the host cell and this inhibits the early stage of replication of the influenza A virus and checks the growth of virus.
What does Symmetrel contain. Symmetrel capsules 100mg contain the active ingredient amantadine hydrochloride, used to treat Parkinson's disease and to treat and prevent symptoms of influenza A virus. They also contain: rape seed oil, lecithin, a wax blend composed of white beeswax and hydrogenated soya and vegetable oils, sodium ethyl hydroxybenzoate, gelatin, glycerol, iron oxide red CI 77491, sorbitol, sodium propyl hydroxybenzoate, titanium dioxide.
Treating Parkinson's disease with Symmetrel Symmetrel capsules 100mg contain amantadine, which is an antiparkinsonian drug used to treat neurological symptoms that cause the abnormal movements associated Parkinsonism and Parkinson's disease. Parkinson's disease is a neurological disorder that is either idiopathic, which means that its cause is unknown, or secondary to a known cause such as stroke, head trauma or as a side effect of medication, particularly neuroleptic antipsychotics.
How should I take Symmetrel?
If you have impaired kidney function, your doctor will alter your dosing interval to one capsule every 2-7 days. This should reduce side effects from the drug. Common side effectsLike all medications, Symmetrel can cause side effect sin some patients. These effects tend to be worse in elderly patients and in those taking other drugs called anticholinergics.
Postural hypotension- A fall in blood pressure when standing quickly. Uncommon side effectsIn a very small number of patients, Symmetrel can cause some more serious side effects. You should tell your doctor immediately if you notice any of the flowing side effects:Signs of allergy such as rash, itching or hives, swelling of the face, lips or tongue angioedema or wheezing and difficulty breathing.
MIMS online- Prescribing Information.
What should I avoid while taking Symmetrel?
Check before you take Amantadine hydrochloride 100mg capsules Do not take Amantadine hydrochloride 100mg capsules: if you are allergic hypersensitive to amantadine hydrochloride or any of the ingredients of Amantadine hydrochloride 100mg capsules see Section 6 Further information if you suffer from fits convulsionsfor example epilepsy if you have ever had an ulcer in your stomach or small intestine if you suffer from any serious kidney disease if you are pregnant or trying to become pregnant see Section 2 Pregnancy and breast-feeding if you are breast-feeding see Section 2 Pregnancy and breast-feeding.
Take special care with Amantadine hydrochloride 100mg capsules Before you take Amantadine hydrochloride 100mg capsules tell your doctor if: you suffer from any liver or kidney disease you have a history of disease involving the heart and blood vessels you are currently suffering from heart problems or heart failure heart problems which cause shortness of breath or ankle swelling you have any mental illness for example, schizophrenia or dementia you have increased pressure in the eyes glaucoma.
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. Taking with food and drink Be careful when drinking alcohol whilst taking Amantadine hydrochloride 100mg capsules, it may affect you more than usual.
Pregnancy and breast-feeding Do not take Amantadine hydrochloride 100mg capsules if you are pregnant or trying to become pregnant. Ask your doctor or pharmacist for advice before taking any medicine. Driving and using machines Taking Amantadine hydrochloride 100mg capsules may make your vision blurred or make you feel dizzy.
Symmetrel side effects
SYMMETREL amantadine hydrochloride should not be discontinued abruptly in patients with Parkinson's disease since a few patients have experienced a parkinsonian crisis, i. The dose of anticholinergic drugs or of SYMMETREL amantadine hydrochloride should be reduced if atropine-like effects appear when these drugs are used concurrently. Abrupt discontinuation may also precipitate delirium, agitation, delusions, hallucinations, paranoid reaction, stupor, anxiety, depression and slurred speech. Sporadic cases of possible Neuroleptic Malignant Syndrome NMS have been reported in association with dose reduction or withdrawal of SYMMETREL amantadine hydrochloride therapy.
Therefore, patients should be observed carefully when the dosage of SYMMETREL amantadine hydrochloride is reduced abruptly or discontinued, especially if the patient is receiving neuroleptics. The early diagnosis of this condition is important for the appropriate management of these patients. Considering NMS as a possible diagnosis and ruling out other acute illnesses e. This may be especially complex if the clinical presentation includes both serious medical illness and untreated or inadequately treated extrapyramidal signs and symptoms EPS.
Common Symmetrel ide effects may include:
These are both important chemicals that control movement.
Symmetrel can cause confusion or disorientation, especially in older people.
Influenza A Treatment SYMMETREL amantadine hydrochloride is also indicated in the treatment of uncomplicated respiratory tract illness caused by influenza A virus strains especially when administered early in the course of illness.
Tell your doctor or pharmacist if you are taking or have recently taken any of the following medicines as they may interfere with Amantadine hydrochloride 100mg capsules:Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture not in the bathroom. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program.
Where can I get more information?
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This medication is not a vaccine.