Generic Name: Sinemet
What is Sinemet?
Usually once dosage of the medication is optimized, any weight loss at the beginning of treatment will be regained. Assuming you take Sinemet for several months, your body weight should begin to normalize - even after an initial fluctuation. Weird dreams: Due to the fact that Sinemet affects neurotransmission, it may affect your sleep - particularly your dreams. You may experience particularly bizarre, vivid, or nightmarish dreams throughout your treatment.
Additionally, your doctor may recommend a sleeping medication that may be helpful for reducing nightmares. Note: Most users are unlikely to experience every last side effect listed above. Those taking Sinemet should understand variables that may influence specific side effects as well as side effect severities.
Influential variables include: Sinemet dosage and Carbidopa-Levodopa ratioco-administered agents, duration of administration, and individual factors e. The dosage of Sinemet that you administer on a daily basis will influence the likelihood that you are to experience side effects, as well as the severity of side effects experienced. Medical documentation suggests that dosages of Sinemet Carbidopa-Levodopa should be carefully optimized by a medical doctor to fit the needs of each particular patient.
The tablets are manufactured in a multiple Carbidopa to Levodopa ratios including 1:4 and 1:10. If dosage of Sinemet is too high for the particular needs of the patient, side effects are more likely to occur.
Caution patients about the potential for sudden sleep onset, impulse control symptoms, depression, suicidal ideation, and hallucinations and monitor for these effects. Healthcare providers should ensure patients take their oral Parkinson's disease medications the morning of the PEG-J procedure.
The daily enteral suspension dose can be titrated as needed, based on response and tolerability after Day 1 and until a stable daily dose is maintained. Once no further adjustments are required to the morning dose, continuous dose, or extra dose, this dosing regimen should be administered daily over 16 hours.
Additional dose adjustments may be necessary over time based on the patient's level of activity and disease progression. At the end of each daily 16-hour infusion, patients will disconnect the pump from the PEG-J and take their night-time dose of oral immediate-release carbidopa-levodopa tablets. Convert the oral levodopa dose from milligrams mg to milliliters mL by multiplying the oral dose by 0.
Add 3 mLs to the morning dose to fill prime the intestinal tube to obtain the total morning dose. Program the pump to deliver the total morning dose, which is usually administered over 10 to 30 minutes.
Do not include the doses of oral immediate-release carbidopa-levodopa taken at night when calculating the levodopa amount. Subtract the first oral levodopa dose in milligrams mg taken by the patient on the previous day from the total oral levodopa dose in milligrams mg taken over 16 waking hours.
How should I take Sinemet?
The three main symptoms are shaking tremormuscle stiffness and slow and unsteady movement. People with Parkinson's disease often walk with a shuffle as they have difficulty in initiating movement. The symptoms of Parkinson's disease are caused by a lack of dopamine, a naturally occurring chemical produced by certain brain cells. Dopamine relays messages in the part of the brain that controls muscle movement.
SINEMET contains two active ingredients, levodopa and carbidopa. Levodopa is a chemical closely related to dopamine which allows the body to make its own dopamine. Carbidopa makes sure that enough levodopa gets to the brain where it is needed.
What should I avoid while taking Sinemet?
What should I know about storage and disposal of this medication. Brand names Brand names of combination products Why is this medication prescribed. What special precautions should I follow. Before taking levodopa and carbidopa,tell your doctor and pharmacist if you are allergic to levodopa and carbidopa any other medications, or any of the ingredients in levodopa and carbidopa tablets, capsules, or suspension.
Ask your pharmacist for a list of the ingredients. Your doctor will probably tell you not to take levodopa and carbidopa.
Sinemet side effects
In some cases, sleep occurred without any feelings of drowsiness beforehand. If you experience increased sleepiness or fall asleep during the day, do not drive or do other possibly dangerous activities until you have discussed this effect with your doctor.
Your risk of this sleep effect is increased by using alcohol or other medications that can make you drowsy. See also Precautions section. Get medical help right away if you have any very serious side effects, including: chest pain.
Abruptly stopping or reducing the dose of this medication may rarely cause a very serious condition called neuroleptic malignant syndrome NMS. A very serious allergic reaction to this drug is rare.
This is not a complete list of possible side effects.
Common Sinemet ide effects may include:
It is also approved to treat parkinsonism Parkinson-like symptoms due to encephalitis inflammation or infection of the brainmanganese poisoning, or carbon monoxide poisoning.
Talk to your doctor about whether you should continue breast-feeding.
Since levodopa competes with certain amino acids, the absorption of levodopa may be impaired in some patients on a high protein diet.
Tell your family members about this risk so that they can call the doctor even if you do not realize that your gambling or any other intense urges or unusual behaviors have become a problem.
Patients should be observed for signs of neuroleptic malignant syndrome while therapy is interrupted, and the usual levodopa regimen should be administered as soon as the patient is able to take oral medication. Eplerenone: Concomitant use of antihypertensive agents with levodopa can result in additive hypotensive effects. Epoprostenol: Concomitant use of antihypertensive agents with levodopa can result in additive hypotensive effects.
Where can I get more information?
Nearly half of all Irish people have inadequate and problematic health literacy skills.
In general, hallucinations present shortly after the initiation of therapy and may be responsive to dose reduction in levodopa.