Generic Name: Risperdal
What is Risperdal?
The potential benefit of stopping alpha1 blocking therapy prior to cataract surgery has not been established and must be weighed against the risk of stopping the antipsychotic therapy. Paediatric populationBefore risperidone is prescribed to a child or adolescent with conduct disorder they should be fully assessed for physical and social causes of the aggressive behaviour such as pain or inappropriate environmental demands.
The sedative effect of risperidone should be closely monitored in this population because of possible consequences on learning ability. A change in the time of administration of risperidone could improve the impact of the sedation on attention faculties of children and adolescents. Risperidone was associated with mean increases in body weight and body mass index BMI.
Baseline weight measurement prior to treatment and regular weight monitoring are recommended. Changes in height in the long-term open-label extension studies were within expected age-appropriate norms.
The effect of long-term risperidone treatment on sexual maturation and height has not been adequately studied. Because of the potential effects of prolonged hyperprolactinemia on growth and sexual maturation in children and adolescents, regular clinical evaluation of endocrinological status should be considered, including measurements of height, weight, sexual maturation, monitoring of menstrual functioning, and other potential prolactin-related effects.
This benign breast enlargement is a non-cancerous growth, though it can cause severe discomfort for a male, along with varying degrees of psychological distress and body image concerns. This condition is often associated with galactorhea which is the milky white discharge that comes from the male's breast, similar to that of a female. Unfortunately, patients who have been diagnosed with this condition will likely have to deal with the abnormal tissue growth regularly, as it may continue to regrow even after surgical treatments in severe cases.
Studies show that if a patient waits longer than a year to treat the condition, the more difficult the removal process will become. We were among the first lawyers to ever try a Risperdal case regarding gynecomastia, and our award was 20 times larger than the previous 4 Risperdal verdicts combined.
In order to remove the glandular breast tissues, the patient will have to undergo a surgical procedure that may include liposuction-assisted mastectomy, subcutaneous mastectomy, laser-assisted liposuction, or a laser-lipolysis procedure that does not use liposuction. As with any medical procedure, there are risks for complications. This study was done just a few years after Risperdal was approved to go out on the market by the FDA.
Within this study they found that in just twelve days on the Risperdal prescription, a 38-year-old male developed male breast and began producing a milky white discharge. The primary connection the researchers made was that due to this drug, the patient's prolactin hormone levels nearly doubled the normal range for males. When the patient's prolactin levels were tested on day 13, doctors found him to be at 48.
From this study, doctors concluded that there are clinical consequences for adolescents taking any form of risperidone. The doctors also warned of possible long term side effects, although there is still not enough research at this time to prove the connection. One settlement came right before a case claiming Risperdal caused the plaintiff's gynecomastia was about to start trial.
How should I take Risperdal?
The majority of that increase was observed within the first 6 months. The average percentiles at baseline and 8 months, respectively, were 56 and 72 for weight, 55 and 58 for height, and 51 and 71 for body mass index. In long-term, open-label trials studies in patients with autistic disorder or other psychiatric disordersa mean increase of 7.
This, in turn, may inhibit reproductive function by impairing gonadal steroidogenesis in both female and male patients. Galactorrhea, amenorrhea, gynecomastia, and impotence have been reported in patients receiving prolactin-elevating compounds. Long-standing hyperprolactinemia when associated with hypogonadism may lead to decreased bone density in both female and male subjects. Monitoring of orthostatic vital signs should be considered in patients for whom this is of concern.
A dose reduction should be considered if hypotension occurs.
What should I avoid while taking Risperdal?
These events were most often of early onset with peak incidence occurring during the first 2 weeks of treatment, and median duration was 16 days.
In most studies, untoward events associated with this exposure were obtained by spontaneous report and recorded by clinical investigators using terminology of their own choosing. Consequently, it is not possible to provide a meaningful estimate of the proportion of individuals experiencing adverse events without first grouping similar types of untoward events into a smaller number of standardized event categories.
In two large studies, adverse events were also elicited utilizing the UKU direct questioning side effect rating scale, and these events were not further categorized using standard terminology. Note: These events are marked with an asterisk in the listings that follow. In the listings that follow, spontaneously reported adverse events were classified using World Health Organization WHO preferred terms.
Risperdal side effects
During premarketing testing, seizures occurred in 0. See also Boxed Warning, WARNINGS: Increased Mortality in Elderly Patients with Dementia-Related Psychosis. As with other drugs that antagonize dopamine D2 receptors, risperidone elevates prolactin levels and the elevation persists during chronic administration. Risperidone is associated with higher levels of prolactin elevation than other antipsychotic agents. Rare cases of priapism have been reported.
She experienced jaundice, fever, and bruising, but eventually recovered after receiving plasmapheresis. The possibility of a suicide attempt is inherent in patients with schizophrenia and bipolar mania, including children and adolescent patients, and close supervision of high-risk patients should accompany drug therapy. Manifestations of this increased sensitivity have been reported to include confusion, obtundation, postural instability with frequent falls, extrapyramidal symptoms, and clinical features consistent with the neuroleptic malignant syndrome.
Common Risperdal ide effects may include:
If you want more information, ask your doctor.
List Risperdal side effects by likelihood and severity.
Your doctor may decide you should take another drug called a mood stabiliser as well as RISPERDAL.
RISPERDAL CONSTA can increase the effects of medicines which slow your reactions.
Other uses for this medicine What special precautions should I follow. What special dietary instructions should I follow. What should I do if I forget a dose. What side effects can this medication cause.
Where can I get more information?
The results of the trials follow:The efficacy of risperidone with concomitant lithium or valproate in the treatment of acute manic or mixed episodes was established in one controlled trial in patients who met the DSM-IV criteria for Bipolar I Disorder.
Steady-state concentrations of 9-hydroxyrisperidone are reached in 5-6 days measured in extensive metabolizers.