Generic Name: Renagel
What is Renagel?
You should not take this medication if you are allergic to sevelamer, or if you have a bowel obstruction. Before taking sevelamer, tell your doctor if you have severe constipation, a blockage in your intestines, a stomach or intestinal disorder, trouble swallowing, or if you have recently had stomach or intestinal surgery.
Avoid taking any other medicines within 1 hour before or 3 hours after you take sevelamer. Before taking sevelamer, tell your doctor if you are taking ciprofloxacin Ciproa heart rhythm medication, or a seizure medication. Need help identifying pills and medications. What should I discuss with my healthcare provider before taking sevelamer Renagel, Renvela.
How should I take sevelamer Renagel, Renvela. What happens if I miss a dose Renagel, Renvela. What happens if I overdose Renagel, Renvela.
What should I avoid while taking sevelamer Renagel, Renvela. What other drugs will affect sevelamer Renagel, Renvela.
The average actual daily dose used in the chronic phase of a one year clinical study was 7 grams of sevelamer. Paediatric populationThe safety and efficacy of this product have not been established in patients below the age of 18 years. Renal impairmentThe safety and efficacy of this product have not been established in predialysis patients. Method of administrationFor oral usePatients should take Renagel with meals and adhere to their prescribed diets.
Patients who are constipated should be monitored carefully while being treated with sevelamer hydrochloride. Renagel treatment should be re-evaluated in patients who develop severe constipation or other severe gastrointestinal symptoms. Fat-soluble vitaminsDepending on diet intake and the nature of end stage renal failure, dialysis patients may develop low vitamin A, D, E and K levels. It cannot be excluded that Renagel can bind fat-soluble vitamins contained in ingested food.
Therefore, in patients not taking these vitamins, monitoring vitamin A, D and E levels and assessing vitamin K status through the measurement of thromboplastin time should be considered and the vitamins should be supplemented if necessary. Additional monitoring of vitamins and folic acid is recommended in patients receiving peritoneal dialysis, since in the clinical study, vitamin A, D, E and K levels were not measured in these patients. Folate deficiencyThere is at present insufficient data to exclude the possibility of folate deficiency during long term Renagel treatment.
Renagel does not contain calcium. Serum calcium levels should be monitored as is done in normal follow-up of a dialysis patient. Elemental calcium should be given as a supplement in case of hypocalcaemia.
How should I take Renagel?
Do not start, stop or change the dosage of any medicine before checking with them first. Sevelamer may interfere with the effectiveness of many drugs by making it more difficult for them to be absorbed by the stomach. Consult your pharmacist about the best times to take your medication s. This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
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What should I avoid while taking Renagel?
Few other side effects include intestinal obstruction, fecal impaction, rash and pruritus. The drug has the ability to significantly bring down serum uric acid. However, this reduction is not associated with any detrimental effects but there are many benefits that can be incurred. Some of these include reduction in gout, uric acid nephrolithiasis and hyperuricemia. Certain drugs can interact with the functioning of Renagel and if you are taking any of the following drugs, it is important that you inform your health care professional before taking the medication:medication for heart rhythm and medications given for treating seizures.
The drug can also interact withYou should stay away from the drug if you are allergic to sevelamer.
Renagel side effects
Furthermore, when administering an oral medication where a reduction in the bioavailability of that medication would have a clinically significant effect on its safety or efficacy, the drug should be administered at least one hour before or three hours after Renagel, or the physician should consider monitoring blood levels of the drug. Patients taking anti-arrhythmic and anti-seizure medications were excluded from the clinical trials.
Special precautions should be taken when prescribing Renagel to patients also taking these medications. In a study designed to assess potential impairment of fertility, female rats were given dietary doses of 0. Male rats were given the same doses and treated for 28 days before mating.
Common Renagel ide effects may include:
Sevelamer was registered on 28 June 2005 for the management of hyperphosphatemia in adult patients with stage 4 and 5 chronic kidney disease.
It can be used in patients undergoing haemodialysis dialysis using a blood filtration machine or peritoneal dialysis where fluid is pumped into the abdomen and an internal body membrane filters the blood.
Call your doctor if you have have trouble swallowing the tablet, or if it feels like it gets stuck in your esophagus after you swallow it.
Renagel taken with meals has been shown to decrease serum phosphorus concentrations in patients with CKD who are on dialysis.
Avoid taking any other medicines within 1 hour before or 3 hours after you take Renagel. Sevelamer can bind to other medications and make them less effective. Before taking Renagel, tell your doctor if you are taking ciprofloxacin Ciproa heart rhythm medication, or a seizure medication.
Where can I get more information?
These amines become partially protonated in the intestine and interact with phosphate molecules through ionic and hydrogen bonding.
Special precautions should be taken when prescribing Renagel to patients also taking these medications.