Generic Name: Plendil
What is Plendil?
Overdosage might be expected to cause excessive peripheral vasodilation with marked hypotension and possibly bradycardia. To obtain up-to-date information about the treatment of overdose, consult your Regional Poison-Control Center. Telephone numbers of certified poison-control centers are listed in the Physicians' Desk Reference PDR.
In managing overdose, consider the possibilities of multiple-drug overdoses, drug-drug interactions, and unusual drug kinetics in your patient.
Felodipine is a member of the dihydropyridine class of calcium channel antagonists calcium channel blockers. In vitro studies show that the effects of felodipine on contractile processes are selective, with greater effects on vascular smooth muscle than cardiac muscle. Negative inotropic effects can be detected in vitrobut such effects have not been seen in intact animals.
The effect of felodipine on blood pressure is principally a consequence of a dose-related decrease of peripheral vascular resistance in man, with a modest reflex increase in heart rate see Cardiovascular Effects.
With the exception of a mild diuretic effect seen in several animal species and man, the effects of felodipine are accounted for by its effects on peripheral vascular resistance.
Following oral administration, felodipine is almost completely absorbed and undergoes extensive first-pass metabolism.
Plendil is designed to block the action of calcium on blood vessels and the heart, allowing the blood vessels to relax and the heart to beat more slowly and with less force. First approved by the FDA in 1991, Plendil won authorization in China four years later.
The transaction does not include the transfer of any AstraZeneca employees or facilities, the company said. Felodipine is used to treat high blood pressure. Felodipine is in a class of medications called calcium channel blockers. It works by relaxing the blood vessels so your heart does not have to pump as hard. High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body.
Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. Do not take more or less of it or take it more often than prescribed by your doctor.
How should I take Plendil?
Add to Cabinet Add Adderall to my medicine cabinet. I amCurrently Taking Researching Previously TakenReason for takingAttention Deficit Disorder with Hyperactivity Recurring Sleep Episodes During the Day Other Did you know. With WebMD's Medicine Cabinet, you can check interactions with drugs. Find a Drug or Condition DrugConditionEnter a drug name. Use the arrow keys to navigate suggestions. Log in Find medicines with the same active ingredientsFind medicines from the same companyPlendil 2.
What should I avoid while taking Plendil?
Ask your doctor or health care professional how you can gradually reduce the dose. If it is almost time for your next dose, take only that dose. Do not take double or extra doses. Visit your doctor or health care professional for regular check ups. Check your blood pressure and pulse rate regularly.
Ask your health care professional what your blood pressure and pulse rate should be, and when you should contact him or her. You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you.
Plendil side effects
Plendil ER is not addictiveBefore you use PLENDIL ERWhen you must not use itDo not use Plendil ER if you are pregnant or breastfeeding unless your doctor says so. Ask your doctor about the risks and benefits involved. PLENDIL ER should not be used during pregnancy unless your doctor thinks that it is the best drug for you.
It may affect your baby if you take it during pregnancy. Your baby can take in very small amounts of Plendil ER from breast milk if you are breastfeeding, but it is unlikely that the amount available to the baby will do any harm.
Do not give Plendil ER to children.
Common Plendil ide effects may include:
However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule.
Especially tell your doctor if you take:This is not a complete list of Plendil drug interactions.
Some conditions may become worse when the drug is suddenly stopped.
Calcium is needed for smooth muscle cells to contract, so by blocking calcium channels, smooth muscle cell contraction is prevented.
Heart disease coronary artery disease occurs when plaque builds up in the coronary arteries, the vessels that supply blood to the heart.
Risk factors for heart disease include: Smoking High blood pressure High cholesterol Diabetes Family history Obesity Angina, shortness of breath, and sweating are just a few symptoms that may indicate a heart attack. Explore heart disease diagnosis, treatment, and prevention.
Where can I get more information?
All medicines have risks and benefits.
Product descriptionWhat Plendil ER looks likePlendil ER 2.