Generic Name: Order paxil
What is Order Paxil?
Monitor patients for signs and symptoms of bleeding. Although clinical trial data indicate that paroxetine is not associated with the development of clinically significant ECG abnormalities in adults, the use of paroxetine has not been systematically evaluated in patients with a recent history of myocardial infarction or unstable cardiac disease. Evaluation of electrocardiograms ECGs of 682 patients who received paroxetine in double-blind, placebo-controlled trials, however, did not indicate that paroxetine is associated with the development of significant ECG abnormalities.
Paroxetine should be used with caution in patients with congenital heart disease or in those who are taking other medications concomitantly that might result in drug interactions. For example, QT prolongation, tachycardias, and other side effects have been reported in children taking clomipramine in combination with paroxetine for the treatment of obsessive-compulsive disorder OCDor in adult patients taking paroxetine a CYP2D6 inhibitor along with medications known to prolong the QT interval that are metabolized by CYP2D6.
Additional monitoring may be necessary, especially when a patient receives combined treatments. Use selective serotonin reuptake inhibitors SSRIsincluding paroxetine, with caution in patients with osteoporosis. Epidemiological studies on bone fracture risk following exposure to SSRIs have reported an association between SSRI treatment and bone fractures. It is unknown to what extent fracture risk is directly attributable to SSRI treatment.
If a paroxetine-treated patient presents with unexplained bone pain, point tenderness, swelling, or bruising, consider the possibility of a fragility fracture.
It may be prescribed to treat other conditions, as well. Paroxetine restores the balance of a brain neurotransmitter called serotonin by inhibiting its reuptake into the nerve cells. This medication should not be administered to anyone younger than 18 years old without the advice of a doctor. This information is for educational purposes only. Not every known side effect, adverse effect, or drug interaction is in this database. If you have questions about your medicines, talk to your health care provider.
This medicine should be taken about the same time every day, morning or evening and can be taken with or without food. It may up to 4 weeks to reach full effect, but you may see symptoms of depression improving in one to two weeks. Make sure that you know how the medicine affects you before driving or performing other hazardous tasks. Talk to your doctor if you are taking certain antibiotics such as erythromycin, clarithromycin or azithromycin.
This medicine should not be taken with MAO inhibitors.
How should I take Order Paxil?
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:An interaction between two medications does not always mean that you must stop taking one of them.
Speak to your doctor about how any drug interactions are being managed or should be managed. Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter non-prescriptionand herbal medications that you are taking. Also tell them about any supplements you take. Health Tool Think you recognize the cycle of Binge Eating Disorder BED.
What should I avoid while taking Order Paxil?
This effect appears to be dose related. An in vivo study suggests that drugs which inhibit CYP2D6, such as paroxetine, will elevate plasma levels of thioridazine. Epidemiological studies have shown that infants exposed to paroxetine in the first trimester of pregnancy have an increased risk of congenital malformations, particularly cardiovascular malformations.
The findings from these studies are summarized below:Other studies have found varying results as to whether there was an increased risk of overall, cardiovascular, or specific congenital malformations. It was not possible in this meta-analysis to determine the extent to which the observed prevalence of cardiovascular malformations might have contributed to that of overall malformations, nor was it possible to determine whether any specific types of cardiovascular malformations might have contributed to the observed prevalence of all cardiovascular malformations.
If a patient becomes pregnant while taking paroxetine, she should be advised of the potential harm to the fetus. For women who intend to become pregnant or are in their first trimester of pregnancy, paroxetine should only be initiated after consideration of the other available treatment options. These studies have revealed no evidence of teratogenic effects.
Order Paxil side effects
Do not stop taking paroxetine without talking to your doctor. Your doctor may decrease your dose gradually. Tell your doctor if you experience any of these symptoms when your dose of paroxetine is decreased. Paroxetine is also sometimes used to treat chronic headaches, tingling in the hands and feet caused by diabetes, and certain male sexual problems. Paroxetine is also used with other medications to treat bipolar disorder mood that changes from depressed to abnormally excited. Talk to your doctor about the possible risks of using this drug for your condition.
Your child's doctor will watch his or her growth carefully. Talk to your child's doctor if you have concerns about your child's growth or weight while he or she is taking this medication.
Common Order Paxil ide effects may include:
First you have been on your antidepressant for an extended period.
Which proposed concepts should we use.
This selectivity causes serotonin levels in the brain to normalize quickly, relieving depression with relatively few side effects.
In these cases, your doctor may want to change the dose, or other precautions may be necessary.
In these studies, the effectiveness of Paxil compared to placebo was evaluated on the basis of 1 the proportion of responders, as defined by a Clinical Global Impression CGI Improvement score of 1 very much improved or 2 much improvedand 2 change from baseline in the Liebowitz Social Anxiety Scale LSAS.
Paroxetine demonstrated statistically significant superiority over placebo on both the CGI Improvement responder criterion and the Liebowitz Social Anxiety Scale LSAS. The effectiveness of Paxil in the treatment of Posttraumatic Stress Disorder PTSD was demonstrated in two 12-week, multicenter, placebo-controlled studies Studies 1 and 2 of adult outpatients who met DSM-IV criteria for PTSD.
Study outcome was assessed by i the Clinician-Administered PTSD Scale Part 2 CAPS-2 score and ii the Clinical Global Impression-Global Improvement Scale CGI-I. The 2 primary outcomes for each trial were i change from baseline to endpoint on the CAPS-2 total score 17 itemsand ii proportion of responders on the CGI-I, where responders were defined as patients having a score of 1 very much improved or 2 much improved.
Where can I get more information?
Doses of 20 mg and 40 mg of PAXIL were demonstrated to be significantly superior to placebo on change from baseline for the CAPS-2 total score and on proportion of responders on the CGI-I.
Do not drink alcohol while using PAXIL.