Generic Name: Ocuflox
What is Ocuflox?
For more information, see the package leaflet provided with the other medicine. Norvir can also be used as an HIV medicine, where it acts directly against the virus. The recommended dose for adults aged 18 years or over is 600 mg twice a day.
Treatment should start with a low dose that is gradually increased over the first 14 days of treatment. This causes an increase of antiviral levels in the blood of such medicines and thus it boosts their antiviral activity. This means that it blocks a viral enzyme called protease, which is involved in the reproduction of HIV. When the enzyme is blocked, the virus does not reproduce normally, slowing down its rate of multiplication.
Norvir, taken in combination with other antiviral medicines, reduces the amount of HIV in the blood and keeps it at a low level. Norvir does not cure HIV infection or AIDS, but it may delay the damage to the immune system and the development of infections and diseases associated with AIDS. Norvir has been studied as a booster in clinical studies that were designed to assess the effects of the antiviral medicines that it is used to boost.
Information on these studies can be found in the EPAR summaries for the other medicines. Norvir has been studied as an antiviral medicine in two main studies involving 1,446 patients.
Deoarece unele dintre aceste substante au un risc recunoscut de a produce reactii adverse grave sau sunt periculoase la concentratii plasmatice mari, ele nu trebuie administrate simultan cu Norvir. Masuri de precautie Norvir este in principal metabolizat si eliminat pe cale hepatica, de aceea administrarea lui la pacienti cu functii hepatice improprii se face cu precautie. Nu se cunoaste daca Norvir este excretat in laptele matern, motiv pentru care Norvir se utilizeaza la mamele care alapteaza numai daca beneficiile depasesc evident riscurile.
Aceleasi precautii vor fi luate si in cazul administrarii Norvir la copii sub 12 ani. Reactii adverse Norvir este in general bine tolerat de pacientii cu infectie HIV, inclusiv de cei aflati intr-un stadiu avansat al bolii. Greata, varsaturile si diareea, precum si paresteziile orale si periferice au fost, statistic, cele mai frecvente reactii adverse ale Norvir. Efectele adverse de tip gastrointestinal apar cel mai frecvent in primele doua saptamani de tratament cu Norvir si sunt, de obicei, limitate ca durata.
Prin navigarea pe acest site, va exprimati acordul asupra folosirii cookie-urilor. Learn More Apply NowNorvir ritonavir is one of the top medications prescribed every year for those struggling with HIV-1 infections. Enroll today in Prescription Hope and begin receiving your Norvir at a price that fits within your budget.
How should I take Ocuflox?
Bottles of 30 tablets each NDC 0074-3333-30. NORVIR Oral Solution, 80 mg per mL Ritonavir NORVIR ritonavir oral solution is an orange-colored liquid, supplied in amber-colored, multi- dose bottles containing 600 mg ritonavir per 7. Product should be stored and dispensed in the original container. North Chicago, IL 60064 USA. Clinical Trial Experience Because clinical trials are conducted under widely varying conditions, adverse reactions rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.
Adverse Reactions In Adults The safety of NORVIR alone and in combination with other antiretroviral agents was studied in 1,755 adult patients.
What should I avoid while taking Ocuflox?
Digoxin levels should be monitored more intensively than usual during this period, with dose adjustments made, as necessary, based on clinical, electrocardiographic and digoxin level findings. Barrier or other non-hormonal methods of contraception should be considered when administering ritonavir at therapeutic or low doses as ritonavir is likely to reduce the effect and change the uterine bleeding profile when co-administered with estradiol-containing contraceptives.
Concomitant use of ritonavir and fluticasone or other glucocorticoids that are metabolised by CYP3A4 is not recommended unless the potential benefit of treatment outweighs the risk of systemic corticosteroid effects, including Cushing's syndrome and adrenal suppression see section 4.
Particular caution should be used when prescribing ritonavir in patients using trazodone. Trazodone is a CYP3A4 substrate and co-administration of ritonavir is expected to increase trazodone levels. Adverse reactions of nausea, dizziness, hypotension and syncope have been observed in single dose interaction studies in healthy volunteers see section 4. The concomitant use of ritonavir is not recommended due to potential increase in riociguat exposure see section 4.
Ocuflox side effects
Close When co-administering NORVIR with other protease inhibitors, see the full prescribing information for that protease inhibitor including contraindication information. Adverse Reactions in Adults The safety of NORVIR alone and in combination with other antiretroviral agents was studied in 1,755 adult patients. Body as a Whole Dehydration, usually associated with gastrointestinal symptoms, and sometimes resulting in hypotension, syncope, or renal insufficiency has been reported.
Endocrine System Cushing's syndrome and adrenal suppression have been reported when ritonavir has been co-administered with fluticasone propionate or budesonide. Skin and subcutaneous tissue disorders Toxic epidermal necrolysis TEN has been reported.
Dosage increase of methadone may be considered.
Common Ocuflox ide effects may include:
While Norvir is rarely used as the only protease inhibitor, and is generally used for protease inhibitor boosting, the decision regarding which dose of Norvir to use should be made by a clinician with experience in treating HIV infection.
Ritonavir blocks the activity of protease and results in the formation of defective viruses that are unable to infect the body's cells.
Norvir or placebo was added to baseline therapy, if any.
Pancreatitis Pancreatitis has been observed in patients receiving NORVIR therapy, including those who developed hypertriglyceridemia.
Dose reduction of NORVIR is necessary when used with other protease inhibitors: atazanavir, darunavir, fosamprenavir, saquinavir, and tipranavir. White film-coated ovaloid tablets debossed with the "a" logo and the code NK providing 100 mg ritonavir. For patient use: exposure of this product to high humidity outside the original or USP equivalent tight container 60 mL or less for longer than 2 weeks is not recommended.
NORVIR ritonavir oral solution is an orange-colored liquid, supplied in amber-colored, multi- dose bottles containing 600 mg ritonavir per 7.
Where can I get more information?
Thereby, increasing the risk of serious haematologic abnormalities, or other serious adverse effects from these agents.
Clinical trials confirmed the safety and efficacy of 300 mg atazanavir once daily with ritonavir 100 mg once daily in treatment experienced patients.