Generic Name: Micardis hct
What is Micardis Hct?
Individual dose titration with each of the two components is recommended before changing to the fixed dose combination. MicardisPlus is not indicated in patients with severe hepatic impairment. Thiazides should be used with caution in patients with impaired hepatic function see section 4. The safety and efficacy of MicardisPlus in children and adolescents aged below 18 have not been established. No data are available. MicardisPlus tablets are for once-daily oral administration and should be taken with liquid, with or without food.
MicardisPlus should be kept in the sealed blister due to the hygroscopic property of the tablets. Tablets should be taken out of the blister shortly before administration see section 6. Angiotensin II receptor antagonists should not be initiated during pregnancy. Unless continued angiotensin II receptor antagonist therapy is considered essential, patients planning pregnancy should be changed to alternative antihypertensive treatments which have an established safety profile for use in pregnancy.
When pregnancy is diagnosed, treatment with angiotensin II receptor antagonists should be stopped immediately, and, if appropriate, alternative therapy should be started see sections 4. MicardisPlus should not be given to patients with cholestasis, biliary obstructive disorders or severe hepatic insufficiency see section 4.
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If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Your use of the content provided in this service indicates that you have read,understood and agree to the End-User License Agreement,which can be accessed by clicking on this link. FDA pregnancy category D. Micardis HCT Patient Information including If I Miss a DoseWhat happens if I miss a dose Micardis HCT.
How should I take Micardis Hct?
Appropriate management of maternal hypertension during pregnancy is important to optimize outcomes for both mother and fetus. In the unusual case that there is no appropriate alternative to therapy with drugs affecting the renin-angiotensin system for a particular patient, apprise the mother of the potential risk to the fetus. Initiation of antihypertensive therapy in patients whose renin-angiotensin system are activated such as patients who are intravascular volume- or sodium-depleted, e.
If hypotension occurs, the patients should be placed in the supine position and, if necessary, given an intravenous infusion of normal saline. A transient hypotensive response is not a contraindication to further treatment which usually can be continued without difficulty once the blood pressure has stabilized. Hepatic Impairment: Thiazide diuretics should be used with caution in patients with impaired hepatic function or progressive liver disease, since minor alterations of fluid and electrolyte balance may precipitate hepatic coma.
What should I avoid while taking Micardis Hct?
Ramipril and Ramiprilat: Co-administration of telmisartan 80 mg once daily and ramipril 10 mg once daily to healthy subjects increases steady-state Cmax and AUC of ramipril 2.
Other Drugs: Co-administration of telmisartan did not result in a clinically significant interaction with acetaminophen, amlodipine, glibenclamide, simvastatin, hydrochlorothiazide or ibuprofen.
When administered concurrently, the following drugs may interact with thiazide diuretics: Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur.
Antidiabetic drugs oral agents and insulin : Dosage adjustment of the antidiabetic drug may be required. Lithium: Should not generally be given with diuretics. Diuretic agents reduce the renal clearance of lithium and add a high risk of lithium toxicity. Non-steroidal anti-inflammatory drugs: In some patients, the administration of a non-steroidal anti-inflammatory agent can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics.
Micardis Hct side effects
Notice and Healthcare Provider Information The following information is intended only for healthcare professionals licensed and practicing in the United States and is designed to be an educational aid that supplements and draws upon the professional training, experience, and knowledge of such healthcare professionals.
Do you certify that you are a healthcare professional licensed and practicing in the United States. If you have diabetes and take MICARDIS, you should not take aliskiren. Hydrochlorothiazide is a diuretic and telmisartan is an orally active angiotensin II antagonist acting on the AT1 receptor subtype. Micardis is available by prescription only. Clinical trials involving more than 2500 patients were conducted to test the effects of telmisartan and hydrochlorothiazide in combination for the treatment of hypertension.
One factorial trial was included where patients were given combinations of telmisartan 20, 40, 80, 160mg or placebo and hydrochlorothiazide 6.
Common Micardis Hct ide effects may include:
There was no significant change in putative PKC-HSP20 phosphorylation with any protocol.
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Acute Myopia and Angle-Closure Glaucoma Hydrochlorothiazide, a sulfonamide, can cause an idiosyncratic reaction, resulting in acute transient myopia and acute angle-closure glaucoma.
Q What forms of Micardis HCT are available.
Given their similar pharmacodynamic properties, these results are also relevant for other ACE-inhibitors and angiotensin II receptor blockers. ACE-inhibitors and angiotensin II receptor blockers should therefore not be used concomitantly in patients with diabetic nephropathy.
ALTITUDE Aliskiren Trial in Type 2 Diabetes Using Cardiovascular and Renal Disease Endpoints was a study designed to test the benefit of adding aliskiren to a standard therapy of an ACE-inhibitor or an angiotensin II receptor blocker in patients with type 2 diabetes mellitus and chronic kidney disease, cardiovascular disease, or both. The study was terminated early because of an increased risk of adverse outcomes.
More about Micardis Hct
Where can I get more information?
Electronic orange book: approved drug products with therapeutic equivalence evaluations.
Healthcare professionals are asked to report any suspected adverse reactions via:There is limited information available for telmisartan with regard to overdose in humans.