Generic Name: Loxitane
What is Loxitane?
Mix the concentrate as directed with orange or grapefruit juice just before it is time for a dose. Loxapine is usually taken several times a day. Follow your doctors instructions. Do not stop taking loxapine without the approval of your doctor.
It may be several weeks before you begin to feel better, and you may require continuous treatment for quite some time. Talk to your doctor before you stop taking this medication.
Store loxapine at room temperature away from moisture and heat. Other, less serious side effects may be more likely to occur. Continue to take loxapine and talk to your doctor if you experience: dizziness or drowsiness, headache, weakness or tremor shakingagitation, an increased heart rate, constipation, dry mouth, or weight gain. The generic alternative is not manufactured by the company that makes the brand product.
Control studies of loxapine succinate and clozapine in treatment of schizophrenia. Treatment of acute schizophrenia with loxapine succinate Loxitane in a controlled study with chlorpromazine. PubMedGoogle ScholarPool D, Bloom W, Mielke DH, Roniger Jr JJ, Gallant DM. A controlled evaluation of loxitane in seventy-five adolescent schizophrenic patients.
A double-blind comparative trial of loxapine and trifluperazine in chronic schizophrenic patients. Google ScholarShopsin B, Pearson E, Gershon S, Collins P. A controlled double-blind comparison between loxapine succinate and chlorpromazine in acute newly hospitalized schizophrenic patients. Controlled study of loxapineand chlorpromazine in the treatment of schizophrenia.
Google ScholarTuason VB, Escobar JI, Garvey M, Schiele B. Loxapine versus chlorpromazine in paranoid schizophrenia: a double-blind study. A six-month double-blind comparison of loxapine succinate and chlorpromazine in chronic schizophrenic patients. Google ScholarWang L, Wang Z, Wang Y. Using loxapine succinate and chlorpromazine for treating schizophrenia.
How should I take Loxitane?
Neuroleptic malignant syndrome NMS has been reported see WARNINGS. Extrapyramidal Symptoms - Neuromuscular extrapyramidal reactions during the administration of LOXITANE have been reported frequently, open during the first few days of treatment. In most patients, these reactions involved parkinsonian-like symptoms such as tremor, rigidity, excessive salivation, and masked facies. Akathisia motor restlessness also has been reported relatively frequently. These symptoms are usually not severe and can be controlled by reduction of LOXITANE dosage or by administration of antiparkinson drugs in usual dosage.
Symptoms of dystonia, prolonged abnormal contractions of muscle groups, may occur in susceptible individuals during the first few days of treatment. While these symptoms can occur at low doses, they occur more frequently and with greater severity with high potency and at higher doses of first generation antipsychotic drugs. An elevated risk of acute dystonia is observed in males and younger age groups.
What should I avoid while taking Loxitane?
Loxapine is not approved by the Food and Drug Administration FDA for the treatment of behavior problems in older adults with dementia. Talk to the doctor who prescribed this medication if you, a family member, or someone you care for has dementia and is taking loxapine. Loxapine comes as a capsule to take by mouth. It is usually taken two to four times a day. Try to take loxapine at around the same times every day.
Loxitane side effects
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How should I take loxapine Loxitane. Take loxapine with a full glass of water. Store at room temperature away from moisture, heat, and light. Loxitane Patient Information including If I Miss a DoseWhat happens if I miss a dose Loxitane. What happens if I overdose Loxitane.
Common Loxitane ide effects may include:
Older adults may be more sensitive to the side effects of this drug, especially dizziness, extrapyramidal symptoms EPSand tardive dyskinesia TD see Side Effects.
Caring for Someone With Schizophrenia MS Flares-Ups and Depression Risk Featured Centers Feeling Short of Breath.
Severe respiratory problems may result from this mixture.
Tell your healthcare provider right away if you have any of these symptoms of bronchospasm after taking loxapine.
LOXITANE is administered, usually in divided doses, two to four times a day. Daily dosage in terms of base equivalents should be adjusted to the individual patient's needs as assessed by the severity of symptoms and previous history of response to antipsychotic drugs. Initial dosage of 10 mg twice daily is recommended, although in severely disturbed patients initial dosage up to a total of 50 mg daily may be desirable.
Dosage should then be increased fairly rapidly over the first seven to ten days until there is effective control of symptoms of schizoprenia.
Where can I get more information?
Do not take if you are breast-feeding.
In some cases, this may be harmful and your doctor may advise you to avoid certain foods.