Generic Name: Lasix
What is Lasix?
For normal adults, 20-80mg dosage will cause prompt diuresis, and then a followup dosage is done 6-8 hours later. In patients with severe edema, dosages can go as high as 600mg per day, due to the absence of kidney functions since it is a loop diuretic. Bodybuilding and DosagesLasix is used by bodybuilders shortly before competitions, and sometimes up to two days beforehand, to excrete excessive water so that they appear hard, defined, and have a ripped physique on stage.
The oral version of the compound is most popular with bodybuilders, but some athletes will use injections the morning of the competition. It is important to time Lasix perfectly or the muscles can become small and flat, and vascularity will be lost. With Lasix, more is definitely not better, and if this powerful diuretic is abused. Another strategy that is implemented deals with combining diuretics. Since Lasix has such a powerful effect on electrolyte and potassium levels, stacking it with a potassium sparing compound like Aldactone is synergetic.
A stack of 50mg of aldactone and 20mg lasix is popular. Lasix should ONLY be used by the most experienced bodybuilders. I don't suggest it to new guys. This stuff can be deadly when abused, and bodybuilders have died after taking too much diuretics.
Because of differences in onset of action, sodium polystyrene sulfonate is often used with these agents. With appropriate monitoring, hypokalemia can be avoided. Solifenacin: Diuretics can increase urinary frequency, which may aggravate bladder symptoms. Risk versus benefit should be addressed in patients receiving diuretics and solifenacin.
Sorbitol: Loop diuretics may increase the risk of hypokalemia especially in patients receiving prolonged therapy with laxatives. Streptomycin: The risk of ototoxicity or nephrotoxicity secondary to aminoglycosides may be increased by the addition of concomitant therapies with similar side effects, including loop diuretics. Streptozocin: Because streptozocin is nephrotoxic, concurrent or subsequent administration of other nephrotoxic agents e.
Succinylcholine: Furosemide-induced hypokalemia can potentiate neuromuscular blockade with nondepolarizing neuromuscular blockers. Sucralfate: According to the manufacturer for furosemide, simultaneous administration of sucralfate and furosemide may reduce its natriuretic and antihypertensive effects.
The intake of furosemide and sucralfate is recommended to be separated by at least two hours. Sulfonylureas: Furosemide may cause hyperglycemia and glycosuria in patients with diabetes mellitus.
Sulindac: If a nonsteroidal anti-inflammatory drug NSAID and a diuretic are used concurrently, carefully monitor the patient for signs and symptoms of decreased renal function and diuretic efficacy. Telavancin: Concurrent or sequential use of telavancin with other potentially nephrotoxic drugs such as loop diuretics may lead to additive nephrotoxicity. Closely monitor renal function and adjust telavancin doses based on calculated creatinine clearance.
How should I take Lasix?
If doses greater than 50 mg are required it is recommended that they be given by slow intravenous infusion.
Children : Parenteral doses for children range from 0. Elderly : In the elderly furosemide is generally eliminated more slowly. Dosage should be titrated until the required response is achieved.
Patients with hypovolaemia or dehydration, anuria or renal failure with anuria not responding to furosemide, renal failure as a result of poisoning by nephrotoxic or hepatotoxic agents or renal failure associated with hepatic coma, severe hypokalaemia, severe hyponatraemia, pre-comatose and comatose states associated with hepatic encephalopathy and breast feeding women. Hypersensitivity to furosemide or any of the excipients of Lasix Injection. Patients allergic to sulphonamides may show cross-sensitivity to furosemide.
Where indicated, steps should be taken to correct hypotension or hypovolaemia before commencing therapy.
What should I avoid while taking Lasix?
It is unknown if bromocriptine is the exact cause of this effect. However, the drug should be used cautiously with other medications known to lower blood pressure such as antihypertensive agents. Monitoring of blood pressure should be considered, especially during the initial weeks of concomitant therapy. Cabergoline should be used cautiously in those receiving antihypertensive agents.
Cabozantinib: Monitor for an increase in cabozantinib-related adverse events if concomitant use with furosemide is necessary, as plasma concentrations of cabozantinib may be increased. In addition, loop diuretics may increase the risk of hypokalemia especially in patients receiving prolonged therapy with laxatives. Canagliflozin: When canagliflozin is initiated in patients already receiving diuretics, symptomatic hypotension can occur.
Lasix side effects
In risperidone placebo controlled trials in elderly patients with dementia, a higher incidence of mortality was observed in patients treated with furosemide plus risperidone when compared to patients treated with risperidone alone or furosemide alone.
Cautions should be exercised and the risks and benefits of this combination or co-treatment should be considered prior to the decision to use. Dehydration should be avoided. The possibility exists of exacerbation or activation of systemic lupus erythematosus hence caution should be taken when administering frusemide to patients with a history of SLE.
This medicinal product contains 6. To be taken into consideration by patients on a controlled sodium diet. Symptomatic hypotension leading to dizziness, fainting or loss of consciousness can occur in patients treated with furosemide, particularly in the elderly, patients on other medications which can cause hypotension and patients with other medical conditions that are risks for hypotension.
Common Lasix ide effects may include:
Onset of Action: The onset of diuresis following oral administration is within 1 hour.
Vilazodone: Patients receiving vilazodone with medications known to cause hyponatremia, such as diuretics, may be at increased risk of developing hyponatremia.
The diuretic action of furosemide may lead to or contribute to hypovolaemia and dehydration, especially in elderly patients.
Inform your doctor if you have dizziness, fatigue, or muscle weakness that stays for a long time.
Thomas Brokken, a racetrack veterinarian in Florida and past president of the American Association of Equine Practitioners AAEProunded out the presentation by reporting in 43 years he has not seen any significant adverse effects other than an occasional allergic reaction to Lasix. Bramlage said he thought it does because a horse loses approximately twenty pounds of fluid from the colon due to urination before a race.
But when used in nearly all horses the effect would be similar in all participants and would produce a level playing field. Most veterinarians, trainers, and horse owners have their own view on Lasix.
Where can I get more information?
Hypertensive patients who cannot be adequately controlled with thiazides will probably also not be adequately controlled with LASIX alone.
Do not squirt onto the back of the throat because this may cause gagging.