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Breastfeeding: No information is available on the passage of procyclidine into human breast milk following administration of Kemadrin. Adverse events of a neurological character such as blurred vision, dizziness, confusion and disorientation have been reported with procyclidine.
For this preparation there is no modern clinical documentation which can be used as support for determining the frequency of adverse reactions. Treatment If procyclidine has been ingested within the previous hour or two or possibly longer in view of its likely effects on gastric motility then activated charcoal should be used to reduce absorption.
Each scored tablet contains5 mg procyclidine hydrochloride and the inactive ingredients corn and potato starch, lactose, and magnesium stearate.
KEMADRIN procyclidine hydrochloride is indicated in the treatment of parkinsonism including the postencephalitic, arteriosclerotic, and idiopathic types. Partial control of the parkinsonism symptoms is the usual therapeutic accomplishment. It can be substituted for all the previous medications in mild and moderate cases.
Safety and effectiveness have not been confirmed. PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Kemadrin, discuss with your doctor the benefits and risks of using Kemadrin during pregnancy. It is unknown if Kemadrin is excreted in breast milk. If you are or will be breast-feeding while you are using Kemadrin, check with your doctor or pharmacist to discuss the risks to your baby.
KEMADRIN STORAGEUse Kemadrin as directed by your doctor. KEMADRIN STORAGEStore Kemadrin at room temperature away from moisture and heat. Do NOT use Kemadrin if:you are allergic to any ingredient in Kemadrinyou have angle-closure glaucomaSome medical conditions may interact with Kemadrin.
Every medicine pack includes a patient information leaflet PILwhich provides information on using the medicine safely. This information is arranged in an A-Z list by active substance. You can also use the search box on the left to find a medicine by generic name or brand name. This is the most up-to-date information for a medicine according to its licence history. MHRA holds data for medicines that are licensed at national level. Some medicines are licensed centrally by the European Medicines Agency EMA.
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In a proportion of patients undergoing neuroleptic treatment, tardive dysknesias will occur. While anticholinergic agents do not cause this syndrome, when given in combination with neuroleptics they may exacerbate the symptoms of tardive dyskinesia or reduce the threshold at which these symptoms appear in predisposed patients.
In such individuals subsequent adjustment of neuroleptic therapy or reduction in anticholinergic treatment should be considered. Patients with mental disorders occasionally experience a precipitation of a psychotic episode when procyclidine is administered for the treatment of the extrapyramidal side effects of neuroleptics. Elderly patients, especially those on high doses of anticholinergics may be more susceptible to the adverse events associated with such therapy see section 4.
Specifically, the elderly patient may be particularly vulnerable to Central Nervous System disturbances such as confusion, impairment of cognitive function and memory, disorientation and hallucinations.
These effects are usually reversible on reduction or discontinuation of anticholinergic therapy. There is no specific information available concerning the use of procyclidine hydrochloride in patients with impaired renal or hepatic function.
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Pregnancy Category Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks. Therapeutic Classification Antiparkinsonian Drugs What is this medicine for : How does it work : How should this medicine be used : Common side effects of this medicine : What do I do if I miss a dose : What precautions should I take when taking this medicine : When do I need to seek medical help : Can I take it with other medicines : Are there any food restrictions : How do I store this medicine : Pregnancy Category : Therapeutic Classification : This medication is an anticholinergic agent, prescribed for Parkinsonism, Parkinsons disease, and drug-induced extrapyramidal syndrome.
Com is the online gateway to your favourite medical and general store, MedPlus At medplusmart. No Yes Request received. Brug af Kemadrin sammen med mad og drikke Du kan tage Kemadrin sammen med mad og drikke. Hvis du holder op med at tage Kemadrin Det er vigtigt, at du ikke pludseligt stopper behandlingen med Kemadrin fra den ene dag til den anden.
Yderligere oplysninger Kemadrin indeholder Aktivt stof: Procyclidinhydrochlorid.
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It works by relaxing smooth muscle, which stops muscle spasms. Some medical conditions may interact with Kemadrin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:Some MEDICINES MAY INTERACT with Kemadrin.
Tell your health care provider if you are taking any other medicines, especially any of the following:This may not be a complete list of all interactions that may occur. Ask your health care provider if Kemadrin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
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TargetKindPharmacological actionActionsOrganismUniProt IDMuscarinic acetylcholine receptor M1P11229 P08172 P08173 P20309 DrugInteractionDrug group1,10-PhenanthrolineThe therapeutic efficacy of Procyclidine can be decreased when used in combination with 1,10-Phenanthroline.
In a proportion of patients undergoing neuroleptic treatment, tardive dysknesias will occur.
The therapeutic efficacy of Procyclidine can be decreased when used in combination with Mefloquine.
What do I do if I miss a dose Take a missed dose as soon as you think about it. What precautions should I take when taking Procyclidine : If you have an allergy to procyclidine or any other part of this drug. When do I need to seek medical help If you think there was an overdose, call your local poison control center or ER right away.
Can I take Procyclidine with other medicines: Sometimes drugs are not safe when you take them with certain other drugs and food. Are there any food restrictions Avoid Alcohol How do I store Procyclidine : Store in a cool, dry place away from the reach of children.
Where can I get more information?
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