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Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results from this medication. Isosorbide dinitrate is usually taken 2 or 3 times per day. Follow your doctor's dosing instructions very carefully. If possible, try to rest or stay seated when you use this medication.

Breaking the pill may cause too much of the drug to be released at one time. If you expect to engage in an activity that may cause angina, take the sublingual tablet about 15 minutes before the activity. If you use the sublingual tablet to treat an angina attack that has already begun, use the medicine at the first sign of chest pain.

Place the tablet under your tongue and allow it to dissolve slowly. Do not chew or swallow it. Before using isosorbide dinitrate to treat a sudden angina attack, your doctor may want you to first use a nitroglycerin sublingual tablet.

Agent-Agent Interactions Agent Name Mode of Interaction Sildenafil Sildenafil inhibits phosphodiesterase type 5, the enzyme responsible for the metabolic degradation of cyclic GM P. Organic nitrates activate guanylate cyclase, which increases cyclic GM P. The combination of sildenafil and isosorbide dinitrate may therefore produce excessive hypotension.

Tadalafil Tadalafil inhibits phosphodiesterase type 5, the enzyme responsible for the metabolic degradation of cyclic GM P. The combination of tadalafil and isosorbide dinitrate may therefore produce excessive hypotension. Vardenafil Vardenafil inhibits phosphodiesterase type 5, the enzyme responsible for the metabolic degradation of cyclic GM P. The combination of vardenafil and isosorbide dinitrate may therefore produce excessive hypotension. Alcohol and other vasodilators Alcohol and other vasodilators may intensify the hypotensive effects of isosorbide dinitrate.

Disopyramide Because disopyramide decreases salivary secretions it inhibits the absorption of sublingually administered isosorbide dinitrate. Read full chapter Chapter:Guanylyl Cyclase, Soluble Andreas Friebe Doris Koesling, in xPharm: The Comprehensive Pharmacology Reference, 2007.

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It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs including any herbal medicines or supplements or following any treatment or regimen.

Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Other brands: IsoDitrate, Isochron, Dilatrate-SRAngina aspirin, amlodipine, metoprolol, carvedilol, atenolol, Coreg, Norvasc, propranolol, nitroglycerin, Nitrostat, More.

Angina Pectoris Prophylaxis aspirin, metoprolol, atenolol, diltiazem, nitroglycerin, nifedipine, Nitrostat, Toprol-XL, Cardizem, isosorbide mononitrate, More. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.

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Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Other brands: IsoDitrate, Isochron, Dilatrate-SRAngina aspirin, amlodipine, metoprolol, carvedilol, atenolol, Coreg, Norvasc, propranolol, nitroglycerin, Nitrostat, More.

Angina Pectoris Prophylaxis aspirin, metoprolol, atenolol, diltiazem, nitroglycerin, nifedipine, Nitrostat, Toprol-XL, Cardizem, isosorbide mononitrate, More. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. To view content sources and attributions, please refer to our editorial policy.

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Common Buy Jasmine Condoms ide effects may include:

  • Administration should begin at onset of symptoms and may be repeated until angina is relieved or side effects are experienced.

  • If you develop chest pain during exercise, taking these tablets before exercise will increase the amount of exercise you can do before chest pain begins.

  • Generico Isosorbide Dinitrate Farmacia online con la capacidad para ordenar medicamentos baratos en linea.

  • There may be a dose-dependent fall in arterial oxygen saturation due to inhibition of hypoxic pulmonary vasoconstriction.

This medicine may cause headaches. These headaches are a sign that the medicine is working. Do not stop using the medicine or change the time you use it in order to avoid the headaches.

Where can I get more information?

  • You have had a heart attack myocardial infarction.

  • A patient anticipating activity likely to cause angina should take one Isordil Sublingual tablet 2.