Generic Name: Jardiance
What is Jardiance?
Administration should begin at onset of symptoms and may be repeated until angina is relieved or side effects are experienced. Sublingual tablets should not be crushed or chewed. Treatment of angina pectoris Dosage 5 mg Oral, chewable tablets Use as an abortive agent should be reserved for those who are intolerant of or unresponsive to sublingual nitroglycerin.
Chewable tables should not be crushed prior to administration. Prevention of angina pectoris Dosage 2. Prevention of angina pectoris Dosage 5-10 mg Oral, chewable tablets Chewable tables should not be crushed prior to administration. Prevention of angina pectoris Dosage 5-40 mg Oral, tablets given every six hours To provide a nitrate-free interval and minimize the likelihood of tolerance, it might be administered 2-3 times daily with the last dose at approximately 7 p.
Prevention of angina pectoris Dosage 40-80 mg Oral, extended release tablets given every 8-12 hours To provide a nitrate-free interval and minimize the likelihood of tolerance, it might be administered twice daily at 8 a.
Contraindications Isosorbide dinitrate is contraindicated in those known to be hypersensitive to organic nitrates. Adverse Effects Adverse effects associated with the use of isosorbide dinitrate include headache, dizziness, nausea, vomiting, hypotension, and rash McEvoy 2004.
Agent-Agent Interactions Agent Name Mode of Interaction Sildenafil Sildenafil inhibits phosphodiesterase type 5, the enzyme responsible for the metabolic degradation of cyclic GM P.
Special warnings about Isordil Check your heart rate and blood pressure regularly while you are taking Isordil. Ask your prescriber or health care professional what your heart rate and blood pressure should be and when you should contact him or her.
Tell your prescriber or health care professional if you feel Isordil is no longer having any effect. Alcohol can make you more dizzy, and increase flushing and rapid heartbeats.
If you are taking Isordil on a regular schedule, do not stop taking Isordil suddenly or your symptoms may get worse. Ask your prescriber or health care professional how to gradually reduce the dose. If you find that Isordil becomes less effective with time you should consult your doctor or pharmacist.
Isordil skin spray should be sprayed onto clean dry skin on the chest from a distance of 20cm 8 inches and then rubbed in gently. Avoid contact with the eyes and do not inhale the spray.
Keep the spray away from naked flames. Isordil is not recommended for use in children. Top Product Title side effects Why Isordil should not be prescribed. Isordil should not be used if you suffer from severe anaemia, closed angle glaucoma, low blood pressure, hypovolaemia low volume of circulating bloodcerebral haemorrhage bleeding in the braincardiac tamponade blood in the sac surrounding the heart which prevents the heart beating properlyconstrictive pericarditis inflammation of the sac surrounding the heart which stops the heart from beating properlyaortic stenosis narrowing of the main artery coming from the heart or mitral valve stenosis narrowing of one of the valves in the heart.
Isordil should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.
How should I take Jardiance?
Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. Before UsingTOP In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. For this medicine, the following should be considered: AllergiesTOP Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines.
PediatricTOP Appropriate studies have not been performed on the relationship of age to the effects of isosorbide dinitrate in the pediatric population.
What should I avoid while taking Jardiance?
See Prescriptions for more details. Please contact our pharmacist for more information. If you order this item as Private, NO PBS stickers will be issued.
Once any prescription order has been sent the product cannot be returned for a refund even if your doctor changes your medication or you have an adverse reaction. Authority prescriptions need to be applied for by the doctor writing the script and can include reasons such as increased quantities due to dosage, increased repeats, use for a pre determined specified use, or the nature of the medication itself requiring specialist interaction.
Before this can be dispensed the doctor has to give approval. The prescription must be written for the total quantity or the prescription must be endorsed by your doctor "Regulation 24" otherwise we will be unable to dispense the increased amount.
Jardiance side effects
Alcohol and other vasodilators Alcohol and other vasodilators may intensify the hypotensive effects of isosorbide dinitrate. Disopyramide Because disopyramide decreases salivary secretions it inhibits the absorption of sublingually administered isosorbide dinitrate.
Read full chapter Chapter:Guanylyl Cyclase, Soluble Andreas Friebe Doris Koesling, in xPharm: The Comprehensive Pharmacology Reference, 2007.
Pharmacological Regulation The organic nitrates glyceryl trinitrate, isosorbide dinitrate, and isosorbide mononitrate, mainly used in the treatment of coronary heart disease, exert their main therapeutic effect by activating soluble GC via NO.
Nitroglycerin is a very short-acting organic nitrate that is available in several formulations.
Common Jardiance ide effects may include:
Isosorbide dinitrate and its major active metabolite, isosorbide mononitrate, are orally administered organic nitrates that are available as extended-release preparations for the prevention of angina.
Corazon Y Los Vasos Sanguineos Farmacia.
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Where can I get more information?
What should I discuss with my healthcare provider before taking isosorbide dinitrate Isordil.
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