Generic Name: Januvia
What is Januvia?
Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Other brands: IsoDitrate, Isochron, Dilatrate-SRAngina aspirin, amlodipine, metoprolol, carvedilol, atenolol, Coreg, Norvasc, propranolol, nitroglycerin, Nitrostat, More. Angina Pectoris Prophylaxis aspirin, metoprolol, atenolol, diltiazem, nitroglycerin, nifedipine, Nitrostat, Toprol-XL, Cardizem, isosorbide mononitrate, More.
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Explore Apps aFeoOverrideAttrRead 'img', 'src' Support Help Center Frequent Questions Sitemap Contact Us About About Drugs. Generic Name: isosorbide dinitrate Dosage Form: Sublingual TabletsIsosorbide dinitrate ISDN is 1,4:3,6-dianhydro-D-glucitol 2,5-dinitrate, an organic nitrate whose structural formula isand whose molecular weight is 236.
Although originally thought to be effective as vasodilators, emerging evidence suggests that the benefits of hydralazine and isosorbide dinitrate are related more to their biologic effects. By favorably altering the nitroso-redox balance in HF,122 the combination of nitrates and hydralazine may prevent myocardial hypertrophy, fibrosis, and apoptosis and may improve vascular compliance Figure 12-4FIGURE 12-4Consequences of disrupting the balance between nitric oxide and superoxide production in the cardiovascular system of patients with heart failure.
The interaction between nitric oxide NO and superoxide O2- plays fundamental roles in cell and organ failure at key sites throughout the cardiovascular system. Isosorbide dinitrate, a drug that stimulates the NO pathway, and hydralazine, an antioxidant that inhibits O2- synthesis, may restore nitroso-redox balance, converting pathologic pathways to physiologic pathways in the heart and blood vessels. Hydralazine has also been shown to have potent antiatherogenic effects.
It is also not known whether these mechanisms of benefit are of greater importance for African Americans than for other racial or ethnic groups. Preliminary studies demonstrate impaired flow-mediated vasodilation in blacks with hypertension compared with whites with hypertension, but these studies are limited by small numbers and potential confounders. Additional studies to understand the genetic and environmental determinants of the effect of hydralazine and nitrates on disease progression in HF are in progress.
Practical Considerations A number of factors have limited the widespread application of hydralazine-isosorbide dinitrate to patients with HF. First, in V-HeFT II, the ACE inhibitor enalapril resulted in a significant improvement in survival compared with hydralazine-isosorbide dinitrate. Although a fixed combination pill that can be taken three times daily is available, adherence and cost remain problematic for patients already taking several HF medications.
Third, this combination has a number of side effects, including headaches and flushing associated with nitrate preparations and gastrointestinal symptoms from hydralazine.
How should I take Januvia?
Comprar Isordil-Sublingual Isosorbida Una marca de Isordil-Sublingual nombrado Cardionil por Alacan, Dolak fabricado por Bama-Geve, Imdur S. Isordil Vademecum Isordil Isosorbide Dinitrate. Isordil Isosorbide dinitrate Isordil previene y alivia el dolor en el pecho anginadebido a la enfermedad arterial coronaria.
Learn about Isordil Isosorbide Dinitrate may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. Realmente Precio Bajo En Isordil Sublingual y Entrega Gratuita En Todo El Mundo.
Consulta el PRECIO DE Isordil isosorbide dinitrate. ISORDIL 10 mg tablet contains 10 mg Isosorbide dinitrate.
What should I avoid while taking Januvia?
Code Definition PA Prior Authorization Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
QL Quantity Limits Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered. ST Step Therapy Drugs that have step therapy associated with each prescription.
Januvia side effects
Isosorbide mononitrate is a nitrate. No pain related info. If pain continues, you can take up to 3 doses, with 5 minutes in between each dose. Call 911 or go to the hospital if you've taken a second dose. Sublingual form works the fastest 1-3 minutes but lasts the shortest in your body 25 minuteswhile the patch form takes the longest to start working 30 minutes but lasts the longest 10-12 hours.
Your doctor can help you find the one that's best for you. You have to stick to a really specific dosing schedule to prevent this from happening. You have to stick to a really specific dosing schedule for the extended-release, ointment, and patch forms to prevent this from happening.
Common Januvia ide effects may include:
Isordil previene y alivia el dolor en el pecho anginadebido a la enfermedad arterial coronaria.
You must not stop taking isosorbide dinitrate to take sildenafil as this will increase your chances of having an angina attack.
This is a decision you and your doctor will make.
What does isosorbide dinitrate look like.
Angina pectoris: ISORDIL Sublingual tablets: For treatment of angina pectoris and for prophylaxis in situations likely to provoke an angina attack i. ISORDIL Oral tablets: For prophylaxis of angina pectoris due to coronary artery disease. The oral tablets are not indicated for the treatment of acute anginal attack, since the onset of this product is not sufficiently rapid to abort acute attack.
For prophylaxis of angina pectoris due to coronary artery disease. The Tembids tablets are not indicated for the treatment of acute anginal attack, since the onset of this product is not sufficiently rapid to abort such an attack.
Where can I get more information?
Drug schedule: schedule 3Available as: isosorbide dinitrate is available as tablets, sublingual tablets, oral spray and as injection.
You have to stick to a really specific dosing schedule to prevent this from happening.