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It is important to work with your doctor to find the right medication at the right dose for you. It is extremely important not to increase your current dose dose without the approval from your doctor. Patti Brown, PharmDA: There was no mention in the prescribing information in regards to an increased risk of lymphoma caused by treatment with Prozac fluoxetine.
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Megan Uehara, PharmDQ: When I first started taking Prozac, I lost my appetite. Side effects can be patient specific. Check with your doctor before making any changes to your drugs or doses. Anorexia poor appetite has been reported in 4 percent to 17 percent of patients studied during clinical trials. Weight loss has also been reported at 2 percent and increased appetite, weight gain and taste perversion have also been reported.
Increases in appetite could be a factor in patients that notice weight gain while being on Prozac. However, please keep in mind that there are many causes for weight gain besides possible side effects from medications. As always, talk with your health care provider regarding questions you have about your medications and associated side effects. Jen Marsico, RPhQ: My doctor increased my dosage of Prozac. Since then, I have been having trouble staying awake in the afternoon, especially after lunch.
Could this extra Prozac be causing this. A: You are probably correct on this one. One of the side effects of Prozac is drowsiness and so this may be what is causing you to be tired in the afternoon. For some people, this effect does go away after a period of time until the drug levels become more level in the body.
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View ArticlePubMedGoogle ScholarMyers JK, Weissman MM, Tischler GL, Holzer CE, Leaf PJ, Orvaschel H, Anthony JC, Boyd JH, Burke JD, Kramer M, et al: Six-month prevalence of psychiatric disorders in three communities 1980 to 1982. View ArticleGoogle ScholarBech P, Cialdella P, Haugh MC, Birkett MA, Hours A, Boissel JP, Tollefson GD: Meta-analysis of randomised controlled trials of fluoxetine v.
British Journal of Psychiatry. View ArticlePubMedGoogle ScholarCox BJ, Swinson RP, Morrison B, Lee PS: Clomipramine, fluoxetine, and behavior therapy in the treatment of obsessive-compulsive disorder: A meta-analysis. Journal of Behavior Therapy and Experimental Psychiatry. View ArticlePubMedGoogle ScholarHoog S, Tepner R, Nilsson ME, Romano S, Kennedy JS: Changes in anxiety, agitation, and insomnia during treatment of depression for patients age 55 years and older: Analysis from fluoxetine double-blind, placebo-controlled trials.
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With 20 years of prescribing and reporting of side effects, there are no known long-term adverse effects related to the medication. Q: Can Prozac weekly give you chest pains and palpitations. A: The prescribing information for Prozac weekly does list palpitations as a frequent side effect of the medication, occurring in 1 out of 100 patients.
You should have a discussion with your physician about any type of chest pain you are experiencing. A: According to the literature available for Prozac fluoxetinechanges in weight were a reported side effect. The studies have shown that various types of dermatologic side effects were reported. If you are experiencing unusual or bothersome symptoms while taking Prozac fluoxetineyou may want to speak to your health care provider to determine the cause.
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Fluoxetine hydrochloride is the first agent of the class of antidepressants known as selective serotonin-reuptake inhibitors SSRIs. Fluoxetine is a racemic mixture of the R- and S- enantiomers and are of equivalent pharmacologic activity.
Despite distinct structural differences between compounds in this class, SSRIs possess similar pharmacological activity. As with other antidepressant agents, several weeks of therapy may be required before a clinical effect is seen. SSRIs are potent inhibitors of neuronal serotonin reuptake.
During acute use, SSRIs block serotonin reuptake and increase serotonin stimulation of somatodendritic 5-HT1A and terminal autoreceptors. Chronic use leads to desensitization of somatodendritic 5-HT1A and terminal autoreceptors.
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Use caution with inhaled forms of budesonide as systemic exposure to the corticosteroid may also increase.
Empagliflozin: Fluoxetine may enhance the hypoglycemic effects of antidiabetic agents.
Use caution during coadministration.
Tipranavir: Use caution when coadministering tipranavir and ritonavir with selective serotonin reuptake inhibitors, as increased SSRI concentrations may be seen.
If one wishes to begin an MAO inhibitor selegiline for cognitive dysfunction or amitraz for parasite control in a patient presently on fluoxetine, a 5 week period is recommended between the last dose of fluoxetine and the first dose of the MAO inhibitor. Similarly, if a patient is on an MAO inhibitor and will be beginning fluoxetine, a two week period is needed between medications. The period is longer in the former incidence because of the very long half-life of fluoxetine in the body.
Exploratory studies have also looked at whether fluoxetine might have a role in reducing inflammation around nerves in multiple sclerosis.
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Giving each dose with some food may help.
Serious and fatal reactions may occur if sertraline and monoamine oxidase MAO inhibitors are taken together.