Generic Name: Generic eldepryl
What is Generic Eldepryl?
This drug may rarely cause an attack of extremely high blood pressure hypertensive crisiswhich may be fatal. Many drug and food interactions can increase this risk.
See also Drug Interactions section. This medication may increase serotonin and rarely cause a very serious condition called serotonin syndrome. The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take.
A very serious allergic reaction to this drug is rare. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: a certain kind of adrenal gland tumor pheochromocytomacerebrovascular disease e.
The usual dose is one tablet daily. Tablets, oral liquid medicine, and dissolve-on-the-tongue lyophilisate tabletsVery common selegiline side-effects these affect more than 1 in 10 people Common selegiline side-effects these affect less than 1 in 10 people Sleeping problems, feeling confused or depressed, hallucinations, blocked nose, sore throat, sweatingNever take more than the prescribed dose.
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Selegiline is also available without a brand name, ie as the generic medicine. Selegiline increases the levels of a substance in the brain called dopamine, and is used in the treatment of Parkinson's disease.
How should I take Generic Eldepryl?
This medicine should not be taken with any of the medicines listed below, because the combination may carry a risk of serious side effects:This medicine will enhance the effect of levodopa treatment. If you are taking levodopa when you start this medicine, your doctor will need to decrease your levodopa dose in order to optimise the beneficial effects, but avoid enhanced side effects. Once your optimal dose of levodopa is reached, you should experience fewer side effects from the combination than you were from levodopa alone.
The manufacturer recommends that medicines containing oestrogens or progestogens eg contraceptives and HRTshould be avoided in people taking selegiline, because these hormones may increase the blood level of selegiline and thus increase the risk of its side effects. The manufacturer recommends that nasal decongestants such as ephedrine and pseudoephedrine should be avoided by people taking this medicine, because the combination may risk causing a hypertensive crisis. The manufacturer also recommends that the following medicines are avoided by people taking selegiline:Selegiline tablets are also available without a brand name, ie as the generic medicine.
The web site does not have answers to all problems. Answers to specific problems may not apply to everyone.
What should I avoid while taking Generic Eldepryl?
Boceprevir: Close clinical monitoring is advised when administering selegiline with boceprevir due to an increased potential for selegiline-related adverse events. If selegiline dose adjustments are made, re-adjust the dose upon completion of boceprevir treatment. Although this interaction has not been studied, predictions about the interaction can be made based on the metabolic pathway of selegiline. Coadministration may result in elevated selegiline plasma concentrations. Brigatinib: Monitor for decreased efficacy of selegiline if coadministration with brigatinib is necessary.
Selegiline is a CYP3A substrate and brigatinib induces CYP3A in vitro.
Generic Eldepryl side effects
AdvertisementUpgrade to remove ads4 termssamanthabailey467STUDYPLAYdrug useantiparkinsons, MAO-B inhibitorsRouteGive am so doesn't interfere with sleep because it is also a stimulantActionInhibits metabolism of dopamine by blocking out an enzyme that normally inactivates dopamine, CNS stimulantAdverse EffectsCauses excessive stimulation of the sympathetic nervous system with hypertension and potential for stroke, agitation, ataxia, bradykinesia, confusion, dizziness, dyskinesia, hallucinations, insomniaAdvertisementUpgrade to remove adsHelpSign upAboutCompanyCommunity GuidelinesFollow usQWait 'Quizlet.
This medication is the only anti-Parkinson's agent that has been found to slow the loss of dopamine, which is responsible for therapeutic effect in Parkinson's disease. Selegiline HCl is often used with levodopa and carbidopa in the treatment of Parkinson's disease because it increases and extends effects of levodopa, and may help to slow the progress of parkinsonism.
This medicine is usually added to the therapy when there is a decrease in response to levodopa. Here is a review of a few trusted and qualitative online pharmacies and drugstores where you can buy selegiline or order cheap Deprenyl and Eldepryl Selegiline Hydrochloride online, get discount coupon, compare prices for antiparkinson drugs, MAO-B inhibitors and many other medications at a low prices to choose the most acceptable offer for you.
Common Generic Eldepryl ide effects may include:
In the US -Call your doctor for medical advice about side effects.
The decision to prescribe selegiline should take into consideration that the MAO system of enzymes is complex and incompletely understood and there is only a limited amount of carefully documented clinical experience with selegiline.
Butabarbital: Monoamine oxidase inhibitors may prolong the effect of some barbiturates.
Pazopanib: Pazopanib is a weak inhibitor of CYP3A4.
Fluoxetine should not be used less than 14 days after discontinuation of selegiline. Since fluoxetine has a very long elimination half life, at least 5 weeks should be allowed after stopping fluoxetine and before starting selegiline.
Selegiline should not be started until 2 weeks after stopping sertraline. For all other serotonin reuptake inhibitors, a time interval of 1 week is recommended between discontinuation of the serotonin reuptake inhibitor and initiation of selegiline. In general, selegiline should not be introduced after a drug that is known to interact with selegiline, until after 5 half lives of that drug have elapsed.
Where can I get more information?
The side effects listed above may not include all of the side effects reported by the medicine's manufacturer.
Code Definition PA Prior Authorization Drugs that require prior authorization.