Generic Name: Generic efavirenz
What is Generic Efavirenz?
Changes to EFV-based regimens after four weeks post-conception will not reduce the risk of neural tube defects and after eight weeks will have minimal effect on risk for other structural malformations. There are theoretical risks that exposure to EFV or other ARV drugs in the second and third trimester of pregnancy could affect neurodevelopment of infants.
However, in the absence of evidence from neurobehavioral development studies, effects of exposure to any ARV drug after the period of organogenesis remain speculative. Women who realise they are pregnant early in gestation can consider substituting EFV with NVP or a PI, or temporarily suspending treatment. Temporarily suspending ARV treatment also has several risks. Women who become pregnant while receiving EFV require counselling and full information on potential risks to the fetus.
Such decisions are complex and underpinned by biomedical as well as socio-cultural considerations. Triple-ARV prophylaxis is used for almost all pregnant women with HIV in these settings. This has compounded difficulties in making the inevitable trade-offs between reproductive and treatment choices.
Based on existing evidence we have outlined general considerations in these scenarios. In particular, as described in current WHO guidelines for resource-constrained settings, the benefits of EFV are likely to outweigh risks for women using contraception.
Females who are able to become pregnant should use 2 effective forms of birth control during treatment and for 12 weeks after stopping treatment with SUSTIVA. A barrier form of birth control should always be used along with another type of birth control. Barrier forms of birth control may include latex or polyurethane condom, contraceptive sponge, diaphragm with spermicide, and cervical cap. Hormonal forms of birth control, such as birth control pills, injections, vaginal rings, or implants may not work during treatment with SUSTIVA.
Talk to your doctor about forms of birth control that may be used during treatment with SUSTIVA. There is a pregnancy registry for women who take antiretroviral medicines during pregnancy.
The purpose of this registry is to collect information about the health of you and your baby. Talk to your doctor about how you can take part in this registry.
Do not breastfeed if you take SUSTIVA. You should not breastfeed if you have HIV because of the risk of passing HIV to your baby. Keep a list of your medicines to show your doctor and pharmacist. You can ask your doctor or pharmacist for a list of medicines that interact with SUSTIVA. Do not start taking a new medicine without telling your doctor. Your doctor can tell you if it is safe to take SUSTIVA with other medicines.
How should I take SUSTIVA.
How should I take Generic Efavirenz?
The risk or severity of adverse effects can be increased when Methapyrilene is combined with Efavirenz. The risk or severity of adverse effects can be increased when Methocarbamol is combined with Efavirenz. The risk or severity of adverse effects can be increased when Methohexital is combined with Efavirenz. Efavirenz may increase the central nervous system depressant CNS depressant activities of Methotrimeprazine.
The risk or severity of adverse effects can be increased when Efavirenz is combined with Methsuximide.
What should I avoid while taking Generic Efavirenz?
Efavirenz is a non-nucleoside reverse transcriptase inhibitor NNRTI. This class of medication attaches to HIV and blocks an enzyme called reverse transcriptase. The HIV virus uses this enzyme to make copies of itself in your body. Your doctor will monitor your levels. You may need to start cholesterol-lowering drugs while taking efavirenz. The rash usually disappears within four weeks.
Generic Efavirenz side effects
Contact your doctor or pharmacist for advice if you have severe liver disease if you are currently taking any of the following medicines: astemizole or terfenadine used to treat allergy symptoms bepridil used to treat heart disease cisapride used to treat heartburn ergot alkaloids for example, ergotamine, dihydroergotamine, ergonovine, and methylergonovine used to treat migraine and cluster headaches midazolam or triazolam used to help you sleep pimozide used to treat certain mental conditions St.
John's wort Hypericum perforatum a herbal remedy used for depression and anxiety. Warnings and precautions Talk to your doctor before taking Efavirenz 600 mg.
Efavirenz 600 mg must be taken with other medicines that act against the HIV virus. If Efavirenz 600 mg is started because your current treatment has not prevented the virus from multiplying, another medicine you have not taken before must b e started at the same time. You can still pass on HIV when taking this medicine, although the risk is lowered by effective antiretroviral therapy. Discuss with your doctor the precautions needed to avoid infecting other people.
This medicine is not a cure for HIV infection and you may continue to develop infections or other illnesses associated with HIV disease.
Common Generic Efavirenz ide effects may include:
Sometimes, if your virus develops resistance to one drug, it will also have resistance to other ARVs.
Women should use barrier and other contraception for 12 weeks after stopping efavirenz.
Combination antiretroviral therapy may also cause raised lactic acid and sugar in the blood, increased fat levels in the blood hyperlipaemia and resistance to insulin.
A barrier form of birth control such as a condom, contraceptive sponge, diaphragm with spermicide, or cervical cap should always be used along with another type of birth control. Tell your doctor right away if you have any of the following symptoms: feeling sad or hopeless, feeling anxious or restless, having thoughts of suicide, have tried to hurt yourself or others, not being able to tell the difference between what is true or real and what is false or unreal, not trusting other people, hearing or seeing things that are not real, or not able to move or speak normally.
Nervous system symptoms are common and can be severe in patients who take SUSTIVA. Symptoms usually begin during the first or second day of treatment and usually go away after 2 to 4 weeks. These symptoms may get worse if you drink alcohol, take a medicine for mental health problems, or use certain street drugs during treatment.
Where can I get more information?
Food and Drug Administration FDA for the treatment of HIV infection in adults and in children 3 months of age and older who weigh at least 7 pounds 12 ounces 3.
Only your health care provider has the knowledge and training to decide which medicines are right for you.