Generic Name: Diamox
What is Diamox?
Sustained release acetazolamide, 500 mg, is also available and may be taken once per day instead of the shorter acting form, though side effects will be more prominent with this dose. I was hit by AMS so made this long post for what it's worth. This is the effect of high altitude on the human body mainly caused by low amounts of oxygen at these altitudes.
This is what many people on the Manali-Leh route report when they travel by road from Manali 6300 feets to Sarchu 14670 feets for the first night halt. Altitude Sickness, Acute Mountain Sickness, hypobaropathy and soroche are all used interchangeably to explain sickness due to effects of high altitude on the human body. Heights of 8000 - 12000 feet is considered High Altitude, 12000-18000 is Very High and above 18000 Extremely High. Most of Ladakh is above 10,000 feet and many passes you have to cross like Baralacha La, Lachung La, Chang La, and Kardung La are all above 16000 feet, where chances of AMS is present.
That day at Kargil and the next day on the road to Rangdum I had classical symptoms like headache on and off, lack of appetite, nausea, breathing difficulty on exertion and drowsiness. On the 3rd day, symptoms gradually disappeared till I reached Leh but for me to be fully back to normal took 6 days of acclimatization.
My other two co-passengers were having mild symptoms like headache, weakness and light-headness, but it lasted only for 2 days for them. A self diagnosis instrument, a questionnaire, recognized world wide for self assessment and clinical assessment called The Lake Louise Assessment System of AMS is available here.
Interactions Drug interactions may change how your medications work or increase your risk for serious side effects. Does Diamox Tablet interact with other medications. Overdose If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. NotesDo not change brands or dosage forms of this medication without consulting your doctor or pharmacist. Do not share this medication with others.
Missed DoseIf you miss a dose, take it as soon as you remember. I amCurrently Taking Researching Previously TakenReason for takingAttention Deficit Disorder with Hyperactivity Recurring Sleep Episodes During the Day Other Did you know. With WebMD's Medicine Cabinet, you can check interactions with drugs.
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How should I take Diamox?
School of MedicineHow it works: CT perfusion with acetazolamide Diamox consists of a baseline CT perfusion scan of a portion of the brain, followed by injection of acetazolamide a vasodilatory agentand then a post acetazolamide CT perfusion scan of the same area.
Normally, if blood flow to the brain is decreased, the vessels for that area will expand to maintain adequate oxygen flow, up to a maximum limit. Usually labs will be needed prior to the study. What to Expect: A baseline perfusion scan is performed, followed by injection of acetazolamide over several minutes.
It takes about 15 minutes for acetazolamide to have its maximal effect. Severe reactions very uncommon. OHSU is an equal opportunity affirmative action institution. Riccelli, MD How it works: CT perfusion with acetazolamide Diamox consists of a baseline CT perfusion scan of a portion of the brain, followed by injection of acetazolamide a vasodilatory agentand then a post acetazolamide CT perfusion scan of the same area.
What should I avoid while taking Diamox?
If the symptoms are bad, then climbers are urged to immediately descend before the AMS devolves into a life-threatening cerebral or pulmonary edema. When to Take Diamox Many guides argue that the best time to take a drug like Diamox is right before bed.
As I know that I don't tend to breathe as deeply at night as during the day, I will usually take Diamox before I go to bed when I'm at high camps on high altitude peaks. On the one hand an evening dose of the drug may help you acclimatize better up high at night.
Alternatives There has been a lot of research over the last few years that indicate that Ginkgo Biloba may work extremely well in acclimatization. As this is easily attainable at health food stores and has few side effects in healthy people, it may be a much better alternative to Diamox. On the other hand, those taking anticoagulants such as ibuprofen, aspirin, warfarin, or antidepressants should be wary of potentially dangerous side effects.
Diamox side effects
This means there is a lower level of fluid around the brain, heart and lungs, aiding breathing. By having this affect on the body, acetazolamide can help to prevent symptoms of altitude sickness occurring. The active ingredient is also used to treat glaucoma. Even in its mildest form, altitude sickness can have a very negative impact on what should otherwise be an enjoyable experience.
In severe cases, it can put your health at serious risk, sometimes requiring hospitalisation. Treatments like acetazolamide Diamox can help to prevent altitude sickness from occurring, and is beneficial for mountain sickness also, provided they are taken alongside appropriate precautionary measures such as acclimatisation and so they can be highly beneficial to people planning on ascending to high altitudes. Additionally this altitude sickness treatment is available in 250mg tablet form, meaning it is very easy to store and take while on the move.
Each 250mg tablet should be swallowed whole with a glass of water, preferably alongside a meal.
Common Diamox ide effects may include:
For cases of fluid retention associated with pre-menstrual tension, a daily dose single of 125 - 375mg is suggested.
Consult your doctor or pharmacist if you have questions about your dosing schedule.
Lithium: Acetazolamide increases lithium excretion and the blood lithium levels may be decreased.
But by NO means should you just figure out for yourself that you should load up that kind of IB into your system.
The usage might differ slightly if used for mountain sickness but you should endeavour to use it as closely to the instructions listed in the patient information leaflet attached with the medication Please note that it is essential to follow the normal methods of altitude sickness prevention even if you are taking medication for it. This rarely occur but if they do whilst using this medication, you may experience: Vomiting Nausea Dizziness Rash Such effects should only be mild and will not last for very long.
This medication should not be taken by anyone who: Has an allergy or hypersensitivity to acetazolamide or any other ingredient contained in it.
Where can I get more information?
Our bottom lineDiamox Acetazolamide is used to treat and prevent mountain sickness, as well as to lower the amount of fluid in the eye and legs.
If you are taking DIAMOX in divided doses, take your tablets at evenly spaced time periods over a 24-hour period.