Generic Name: Order detrol
What is Order Detrol?
There is no generic Detrol at this time 2010. Detrol's basic patent is set to expire September 2012, and Detrol LA -- the long-acting version of Detrol -- has three patents set to expire between 2012 and 2020. Toviaz is just another way to virtually extend the patent life of Detrol by tweaking the molecule into a new molecular entity. This allows Pfizer to continue to compete with generic Detrol when it becomes available after the patent expires in 2012.
Thank you John Mack for getting the correct information out there. For that reason, efficacy of Toviaz is higher than Detrol LA - this is why in the H2H they compared 4mg Detrol with 8mg Toviaz. It isn't about it being a new drug as such, they have just found a way of dosing higher than they could with Detrol. I am scared to death to take the Toviaz because of what the Vesicare did to me. Can anyone tell me since I was able to take the Detrol LA with no side effects if the Toviaz will do the same as the Detrol.
I really need this medication but don't want to be scared to death thinking I am having a heart attack. Talk to your doctor. The problem about asking my Dr.
The most common side effects observed in patients taking Detrol LA plus Flomax were dry mouth 21 percentheadache 6 percentnasal congestion 4 percent and constipation 4 percent. The effect of treatment with Detrol LA on flow rate and postvoid residual was similar to placebo. Symptoms suggestive of urinary retention were reported by two men in the Detrol LA plus Flomax arm, three men in the Detrol LA alone arm, four men in the placebo arm and no one in the Flomax alone arm. Two men required catheterization: one in the Detrol LA plus Flomax arm and one in the Detrol LA alone arm.
Detrol LA is indicated for the treatment of overactive bladder with symptoms of urge incontinence, urgency and frequency. Detrol LA should be used with caution in patients with clinically significant bladder outflow obstruction, gastrointestinal obstructive disorders, controlled narrow-angle glaucoma, and significantly reduced hepatic or renal function.
Flomax is indicated for the treatment of male urinary symptoms due to benign prostatic hyperplasia BPH - enlargement of the prostate. Below are Detrol LA Tolterodine reviews, ratings, comments submitted by patients and caregivers. The effectiveness score is 7 and the side effect score is 7.
The scores are on ten point scale: 10 - best, 1 - worst. This information is not vetted and should not be cosidered as clinical evidence.
How should I take Order Detrol?
CYP2D6 extensive metabolizers had low serum concentrations of tolterodine and high concentrations of the active metabolite 5-HMT, while poor metabolizers had high concentrations of tolterodine and negligible active metabolite concentrations. A total of 710 pediatric patients 486 on DETROL LA, 224 on placebo aged 5-10 with urinary frequency and urge incontinence were studied in two randomized, placebo-controlled, double-blind, 12- week studies.
No overall differences in safety were observed between the older and younger patients treated with tolterodine. In multiple-dose studies in which tolterodine immediate release 4 mg 2 mg bid was administered, serum concentrations of tolterodine and of 5-HMT were similar in healthy elderly volunteers aged 64 through 80 years and healthy young volunteers aged less than 40 years.
In another clinical study, elderly volunteers aged 71 through 81 years were given tolterodine immediate release 2 or 4 mg 1 or 2 mg bid. In a study of tolterodine immediate release conducted in cirrhotic patients Child-Pugh Class A and Bthe elimination half-life of tolterodine immediate release was longer in cirrhotic patients mean, 7.
The clearance of orally administered tolterodine immediate release was substantially lower in cirrhotic patients 1. The recommended dose for patients with mild to moderate hepatic impairment Child-Pugh Class A or B is DETROL LA 2 mg once daily.
What should I avoid while taking Order Detrol?
Detrol is associated with anticholinergic central nervous system CNS effects including dizziness and somnolence see ADVERSE REACTIONS. Patients should be monitored for signs of anticholinergic CNS effects, particularly after beginning treatment or increasing the dose. Advise patients not to drive or operate heavy machinery until the drug's effects have been determined.
If a patient experiences anticholinergic CNS effects, dose reduction or drug discontinuation should be considered. DETROL should be used with caution in patients with myasthenia gravis, a disease characterized by decreased cholinergic activity at the neuromuscular junction. However, the confidence intervals overlapped. These observations should be considered in clinical decisions to prescribe DETROL for patients with a known history of QT prolongation or patients who are taking Class IA e.
There has been no association of Torsade de Pointes in the international post-marketing experience with DETROL or DETROL LA.
Order Detrol side effects
In the US -Call your doctor for medical advice about side effects. List Detrol side effects by likelihood and severity. What should I know regarding pregnancy, nursing and administering Detrol to children or the elderly. Interactions Drug interactions may change how your medications work or increase your risk for serious side effects.
Does Detrol interact with other medications. Overdose If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. NotesDo not share this medication with others.
Common Order Detrol ide effects may include:
Tolterodine may cause a condition that affects the heart rhythm QT prolongation.
If you miss a dose of DETROL, just take your next regular dose at your next regular time.
When traveling with your medication: Always carry your medication with you or in your carry-on bag.
The efficacy endpoints for studies 008, 009, and 010 see Table 4 were identical to the above endpoints with the exception that the number of incontinence episodes was per 24 hours averaged over 7 days.
Medicines like Detrol LA can cause blurred vision or drowsiness. Use caution while driving or doing other dangerous activities until you know how Detrol LA affects you. Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Detrol LA there are no specific foods that you must exclude from your diet when receiving Detrol LA.
Where can I get more information?
Other medications may also interact negatively to cause this condition.
Based on these findings, other potent CYP3A4 inhibitors may also lead to increases of tolterodine plasma concentrations.