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Valproate can cause major congenital malformations, particularly neural tube defects e. In addition, valproate can cause decreased IQ scores following in utero exposure. Valproate should only be used to treat pregnant women with epilepsy or bipolar disorder if other medications have failed to control their symptoms or are otherwise unacceptable. Valproate should not be administered to a woman of childbearing potential unless the drug is essential to the management of her medical condition.

This is especially important when valproate use is considered for a condition not usually associated with permanent injury or death e. Cases of life-threatening pancreatitis have been reported in both children and adults receiving valproate.

Some of the cases have been described as hemorrhagic with a rapid progression from initial symptoms to death. Cases have been reported shortly after initial use as well as after several years of use. If pancreatitis is diagnosed, valproate should ordinarily be discontinued.

What should I discuss with my healthcare provider before taking Valproate. Symptoms of your condition that bother you the most If you have thoughts of suicide or harming yourself Medications you have taken in the past for your condition, whether they were effective or caused any adverse effects If you experience side effects from your medications, discuss them with your provider.

Some side effects may pass with time, but others may require changes in the medication. Any other psychiatric or medical problems you have All other medications you are currently taking including over the counter products, herbal and nutritional supplements and any medication allergies you have Other non-medication treatment you are receiving, such as talk therapy or substance abuse treatment.

Your provider can explain how these different treatments work with the medication. If you are pregnant, plan to become pregnant, or are breast-feeding If you drink alcohol or use illegal drugs How should I take Valproate.

Valproate is usually is taken 1-3 times daily. It may be taken with or without food. Valproate tablets: Swallow whole. What should I avoid while taking Valproate. What happens if I overdose with Valproate.

A specific treatment to reverse the effects of valproate does not exist. What are the possible side effects of Valproate.

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Because most trials included in the analysis did not extend beyond 24 weeks, the risk of suicidal thoughts or behavior beyond 24 weeks could not be assessed.

The risk of suicidal thoughts or behavior was generally consistent among drugs in the data analyzed. The finding of increased risk with AEDs of varying mechanisms of action and across a range of indications suggests that the risk applies to all AEDs used for any indication. The risk did not vary substantially by age 5-100 years in the clinical trials analyzed.

Anyone considering prescribing Depakote or any other AED must balance the risk of suicidal thoughts or behavior with the risk of untreated illness.

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What are the side effects of Depakote. What are the advantages of Depakote. Sign In Drugs Diseases Interaction Check Pill ID Calculators Tables Guidelines Please enable cookies to gain full access to the webpage.

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Do not stop taking valproate, even when you feel better. Only your healthcare provider can determine the length of valproate treatment that is right for you. Do not stop taking valproate or change your dose without talking to with your healthcare provider first. In order for valproate to work properly, it should be taken everyday as ordered by your healthcare provider.

Periodically, your healthcare provider may ask you to provide a blood sample to make sure the appropriate level of medication is in your body and to assess for side effects, such as changes in blood cell counts.

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  • In all states except Tennessee, GoodRx is considered a marketer of prescription discount cards, and is not required to register as a discount card provider.

  • The dose you take and how often depends on what you are being treated for and your condition.

  • Look on the Manufacturer Info page to link to pharmaceutical company pages.

  • When appropriate, counsel these patients about alternative therapeutic options.

Where can I get more information. Divalproex sodium may also be used for purposes not listed in this medication guide. Next Page:What should I discuss with my healthcare provider before taking divalproex sodium Depakote, Depakote ER, Depakote Sprinkles.

Where can I get more information?

  • I was then switched to kepra when i was 18 after i refused to take any medicine that interfered with my life so much.

  • Until then, if you can live with the side effects then its your choice.