Generic Name: Generic crixivan
What is Generic Crixivan?
How should I take CRIXIVAN. There are six important things you must do to help you benefit from CRIXIVAN: Take CRIXIVAN capsules every day as prescribed by your doctor.
Continue taking CRIXIVAN unless your doctor tells you to stop. Take the exact amount of CRIXIVAN that your doctor tells you to take, right from the very start. To help make sure you will benefit from CRIXIVAN, you must not skip doses or take "drug holidays". If you don't take CRIXIVAN as prescribed, the activity of CRIXIVAN may be reduced due to resistance. Take CRIXIVAN capsules every 8 hours around the clock, every day. It may be easier to remember to take CRIXIVAN if you take it at the same time every day.
Discontinuation of indinavir should be considered in all patients with severe leukocyturia. Perform hepatitis B virus HBV screening in any patient who presents with HIV infection to assure appropriate treatment.
Patients with hepatitis B and HIV coinfection should be started on a fully suppressive antiretroviral ARV regimen with activity against both viruses regardless of CD4 counts. If tenofovir cannot be used, entecavir should be used in combination with a fully suppressive ARV regimen note: entecavir should not be considered part of the ARV regimen. Avoid using single-drug therapy to treat HBV i. Further, HBV treatment regimens that include adefovir or telbivudine should also be avoided, as these regimens are associated with higher incidence of toxicities and increased rates of HBV treatment failure.
Most coinfected patients should continue treatment indefinitely with the goal of maximal HIV suppression and prevention of HBV relapse. If treatment must be discontinued, monitor transaminase concentrations every 6 weeks for the first 3 months, and every 3 to 6 months thereafter. Instruct coinfected patients to avoid consuming alcohol, and offer vaccinations against hepatitis A and hepatitis B as appropriate. Indinavir should be used with caution in patients with hepatic disease, including cirrhosis.
Indinavir is metabolized by the liver, so patients with mild to moderate hepatic dysfunction tend to have increased serum levels of indinavir and require a dosage adjustment. Patients with diabetes mellitus or hyperglycemia may experience an exacerbation of their condition during indinavir treatment.
How should I take Generic Crixivan?
Conivaptan: Coadministration of conivaptan with strong CYP3A4 inhibitors like indinavir is contraindicated. The plasma concentrations of both drugs may be elevated during concurrent use. According to the manufacturer of conivaptan, concomitant use of conivaptan with CYP3A4 substrates should be avoided. Subsequent treatment with CYP3A substrates may be initiated no sooner than 1 week after completion of conivaptan therapy.
Patients should be instructed to report any estrogen- related adverse events. Women receiving hormonal contraceptives and anti-retroviral protease inhibitors PIssuch as indinavir, should be instructed to report any breakthrough bleeding or other adverse effects to their prescribers. Coadministration of a single dose of crizotinib with another strong CYP3A4 inhibitor increased the crizotinib AUC and Cmax by 3.
What should I avoid while taking Generic Crixivan?
The serum concentration of the active metabolites of Trastuzumab emtansine can be increased when Trastuzumab emtansine is used in combination with Indinavir. Avoid excessive or chronic alcohol use. Avoid taking with grapefruit juice Take on empty stomach: 1 hour before or 2 hours after meals. Kontakt lege apotek eller sykepleier dersom du opplever bivirkninger, inkludert mulige bivirkninger som ikke er nevnt i dette pakningsvedlegget.
Hva CRIXIVAN er og hva det brukes motHva CRIXIVAN erCRIXIVAN inneholder et virkestoff som kalles indinavir.
Generic Crixivan side effects
TargetKindPharmacological actionActionsOrganismUniProt IDPol polyproteinQ72874 Hepatic. SubstrateEnzymesProductIndinavir Cytochrome P450 3A4DrugInteractionDrug group16-BromoepiandrosteroneThe serum concentration of 16-Bromoepiandrosterone can be increased when it is combined with Indinavir.
The serum concentration of 19-norandrostenedione can be increased when it is combined with Indinavir. The therapeutic efficacy of Acetohexamide can be decreased when used in combination with Indinavir. The serum concentration of Acetylsalicylic acid can be decreased when it is combined with Indinavir.
Common Generic Crixivan ide effects may include:
In patients with mild to moderate hepatic impairment due to cirrhosis, reduce the recommended dose to 600 mg PO every 8 hours.
The team knew that HIV could rapidly develop resistance to any single therapy, and so from the very beginning HIV protease inhibitors were taken in a "cocktail" with other antiretroviral drugs as part of HAART Highly Active AntiRetroviral Therapy.
Cobicistat is an inhibitor of CYP3A4, while both atazanavir and indinavir are CYP3A4 substates.
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In all clinical studies, with the exception of ACTG 320, the AMPLICOR HIV MONITOR assay was used to determine the level of circulating HIV RNA in serum. This is an experimental use of the assay. HIV RNA results should not be directly compared to results from other trials using different HIV RNA assays or using other sample credits.
RxList does not provide medical advice, diagnosis or treatment. Delavirdine Dose reduction of CRIXIVAN to 600 mg every 8 hours should be considered when administering delavirdine 400 mg three times a day.
Where can I get more information?
Compare HIV protease inhibitors.
Your blood sugar can go up while you take indinavir.