Generic Name: Order cozaar
What is Order Cozaar?
Pharmacokinetics of losartan and its active metabolite were generally similar across the studied age groups and similar to historical pharmacokinetic data in adults. The principal pharmacokinetic parameters in adults and children are shown in the table below. Following oral administration in patients with mild to moderate alcoholic cirrhosis of the liver, plasma concentrations of losartan and its active metabolite were, respectively, 5-times and about 1. Use a starting dose of 25 mg for patients with mild to moderate hepatic impairment.
No clinically significant drug interactions have been found in studies of losartan potassium with hydrochlorothiazide, digoxin, warfarin, cimetidine and phenobarbital.
These data suggest that the conversion of losartan to its active metabolite is mediated primarily by P450 2C9 and not P450 3A4. The antihypertensive effects of COZAAR were demonstrated principally in 4 placebo-controlled, 6- to 12- week trials of dosages from 10 to 150 mg per day in patients with baseline diastolic blood pressures of 95-115. Three additional studies examined the antihypertensive effects of losartan and hydrochlorothiazide in combination.
The 4 studies of losartan monotherapy included a total of 1075 patients randomized to several doses of losartan and 334 to placebo. The 10- and 25-mg doses produced some effect at peak 6 hours after dosing but small and inconsistent trough 24 hour responses. Addition of a low dose of hydrochlorothiazide 12.
The terminal elimination half lives of losartan and EXP3174 are about 1. Losartan and other angiotensin-receptor antagonists exhibit fetal toxicity and should be avoided during pregnancy, particularly in the second and third trimesters. Am J Hypertens 21:1157-1162. OX1 Agonists: Orexin A, B Antagonists: ACT-335827 ACT-462206 Almorexant Filorexant Lemborexant SB-334867 SB-408124 SB-649868 Suvorexant TCS-1102 Agonists: Orexin A, B SB-668875 Antagonists: ACT-335827 ACT-462206 Almorexant EMPA Filorexant JNJ-10397049 Lemborexant MK-1064 SB-649868 Seltorexant Suvorexant TCS-1102 TCS-OX2-29 See here instead.
Losartan is an angiotensin II receptor antagonist. Losartan is used to treat high blood pressure hypertension. Losartan is used to slow long-term kidney damage in people with type 2 diabetes who also have high blood pressure. What is the most important information I should know about losartan Cozaar. Stop using and tell your doctor right away if you become pregnant. Use effective birth control. Before you use losartan, tell your doctor about all your other medical conditions and allergies.
Also make sure your doctor knows if you are pregnant or breast-feeding. In some cases, you may not be able to use losartan, or you may need a dose adjustment or special precautions. Certain other drugs may interact with losartan or should not be used at the same time.
How should I take Order Cozaar?
In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.
Losartan comes as a tablet to take by mouth. It is usually taken once or twice a day with or without food. To help you remember to take losartan, take it at around the same time s every day.
Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take losartan exactly as directed.
What should I avoid while taking Order Cozaar?
Dual blockade of RAAS through the combined use of ACE-inhibitors, angiotensin II receptor blockers or aliskiren is therefore not recommended see sections 4. If dual blockade therapy is considered absolutely necessary, this should only occur under specialist supervision and subject to frequent close monitoring of renal function, electrolytes and blood pressure. ACE-inhibitors and angiotensin II receptor blockers should not be used concomitantly in patients with diabetic nephropathy.
Concomitant use with other substances which may induce hypotension as an adverse reaction like tricyclic antidepressants, antipsychotics, baclofen and amifostine may increase the risk of hypotension.
Losartan is predominantly metabolised by cytochrome P450 CYP 2C9 to the active carboxy-acid metabolite. The clinical relevance of this effect is unknown. No difference in exposure was found with concomitant treatment with fluvastatin weak inhibitor of CYP2C9.
Order Cozaar side effects
What brand names are available for losartan. Is losartan available as a generic drug. Do I need a prescription for losartan. What are the side effects of losartan. Losartan may reduce kidney function in some patients and should not be used by patients who have bilateral renal artery stenosis narrowing of both arteries going to the kidneys.
Know the warning signs and symptoms of high blood pressure. Read about high blood pressure medications, diet, and long term treatments.
Common Order Cozaar ide effects may include:
Ask your pharmacist for a list of the ingredients.
Cozaar Rating 52 User Reviews 6.
Take the container with you, even if it is empty.
Symptoms can include: swelling in your feet, ankles, or hands unexplained weight gain Part 7 of 12 Losartan interactions Losartan can interact with other medications, vitamins, or herbs you may be taking.
As with many other medicines used to treat high blood pressure, COZAAR may cause dizziness or light-headedness in some people. Make sure you know how you react to COZAAR before you drive a car, operate machinery, or do anything else that could be dangerous if you are dizzy or light-headed.
If you drink alcohol, dizziness or light-headedness may be worse. Some self-help measures suggested below may help your condition.
Where can I get more information?
This drug may make you dizzy.
The pharmacist can prepare a liquid form of this medication for your child.