Generic Name: Cozaar
What is Cozaar?
It is also important to know what kind of reaction you have to this medicine before undertaking any activity such as driving a car since these side effects may affect these particular activities thus rendering it unsafe e. However, all medicines may or may not cause some side effects to occur in any patient. It is therefore advised to consult with a doctor if you feel anything out of the ordinary occurring after taking this medicine.
Causes Losartan can be taken in orally on an empty or full stomach. In order to experience its full benefit, this medicine should be consumed on a regular basis without missing a single dose. If a dose has been missed then it should be taken immediately. If the time is close for the next dose then you can disregard the missed dose and continue on your regular dosing schedule.
It is important to take only 1 dosage as regulated in the dosing schedule. The shelf life of this medicine depends on when it was manufactured.
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Losartan brand name Cozaar is an angiotensin II receptor blocker ARB. It is one of the Top 250 Drugs similar to the Top 200 Drugs or Top 300 Drugs in ClinCalc. Do you wish you could review the top 250 drugs from beginning to end. Accessed June 25, 2017. Cozaar losartan is also used to decrease the risk of stroke in people who have high blood pressure and a heart condition called left ventricular hypertrophy enlargement of the walls of the left side of the heart.
Cozaar losartan may not decrease the risk of stroke in African Americans who have these conditions.
How should I take Cozaar?
The use of AIIRAs is contraindicated during the 2nd and 3rd trimesters of pregnancy see sections 4. Whilst there is no controlled epidemiological data on the risk with Angiotensin II Receptor Inhibitors AIIRAssimilar risks may exist for this class of drugs.
When pregnancy is diagnosed, treatment with AIIRAs should be stopped immediately and, if appropriate, alternative therapy should be started. Exposure to AIIRA therapy during the second and third trimesters is known to induce human fetotoxicity decreased renal function, oligohydramnios, skull ossification retardation and neonatal toxicity renal failure, hypotension, hyperkalaemia see section 5.
Should exposure to AIIRAs have occurred from the second trimester of pregnancy, ultrasound check of renal function and skull is recommended. Infants whose mothers have taken AIIRAs should be closely observed for hypotension see sections 4.
Based on the pharmacological mechanism of action of hydrochlorothiazide, its use during second and third trimesters may compromise foeto-placental perfusion and may cause foetal and neonatal effects like icterus, disturbance of electrolyte balance and thrombocytopenia.
What should I avoid while taking Cozaar?
In nondiabetic hypertensive patients with proteinuria, the administration of losartan potassium significantly reduces proteinuria, fractional excretion of albumin and IgG.
Losartan maintains glomerular filtration rate and reduces filtration fraction. Losartan has no effect on autonomic reflexes and no sustained effect on plasma norepinephrine. In patients with left ventricular failure, 25 mg and 50 mg doses of losartan produced positive hemodynamic and neurohormonal effects characterized by an increase in cardiac index and decreases in pulmonary capillary wedge pressure, systemic vascular resistance, mean systemic arterial pressure and heart rate and a reduction in circulating levels of aldosterone and norepinephrine, respectively.
The occurrence of hypotension was dose related in these heart failure patients. LIFE StudyThe Losartan Intervention For Endpoint reduction in hypertension LIFE study was a randomised, triple-blind, active-controlled study in 9193 hypertensive patients aged 55 to 80 years with ECG-documented left ventricular hypertrophy. Other antihypertensives, with the exception of ACE inhibitors, angiotensin II antagonists or beta-blockers were added if necessary to reach the goal blood pressure.
Dual Blockade Two large randomised, controlled trials ONTARGET ONgoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial and VA NEPHRON-D The Veterans Affairs Nephropathy in Diabetes have examined the use of the combination of an ACE-inhibitor with an angiotensin II receptor blocker.
Cozaar side effects
What brand names are available for losartan. Is losartan available as a generic drug. Do I need a prescription for losartan. What are the side effects of losartan. Losartan may reduce kidney function in some patients and should not be used by patients who have bilateral renal artery stenosis narrowing of both arteries going to the kidneys. Know the warning signs and symptoms of high blood pressure.
Common Cozaar ide effects may include:
You may need medical attention.
Metformin should be used with caution because of the risk of lactic acidosis induced by possible functional renal failure linked to hydrochlorothiazide.
It is unknown if this drug passes into breast milk.
Common side effects of Cozaar include stuffy nose, back pain, and dizziness.
All medicines have risks and benefits. Your doctor has weighed the risks of you taking COZAAR against the benefits they expect it will have for you. COZAAR is also used to slow the progression of kidney disease in people who have type 2 diabetes mellitus also known as non-insulin dependent diabetes with protein in their urine which doctors call proteinuria.
Where can I get more information?
Cozaar can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.
Hydrochlorothiazide:Hydrochlorothiazide is excreted in human milk in small amounts.