Generic Name: Coumadin
What is Coumadin?
Results in impaired absorption of vitamin K. Health Congestive Heart Failure and Coumadin Congestive Heart Failure and Coumadin by Niya Jones Coumadin therapy requires regular monitoring with periodic blood tests.
Sluggish blood flow due to heart failure can increase the risk of blood clots as well as abnormal heart rhythms that can lead to stroke. A blood thinner called warfarin Coumadin can help reduce the likelihood of blood clots. Coumadin itself can also cause side effects, however.
According to American College of Cardiology guidelines, the risks and benefits of Coumadin must be weighed carefully in people with heart failure. More than 5 million people in the U.
As heart failure progresses, the heart muscle becomes weaker and blood tends to pool in the heart and blood vessels. Stagnant blood flow heightens the risk of blood clots that can travel to the lungs or brain. Blood clots that travel to the brain are the leading cause of strokes.
People with heart failure who also have an irregular heartbeat called atrial fibrillation are at higher risk for a stroke due to a blood clot than are people without heart failure. The medication Coumadin has been used for decades to prevent blood clots.
There is a chance that gene variants that have not been tested can affect warfarin response. This can reduce the accuracy of the predicted warfarin dose level needed intermediate, higher or lower. It is also possible that technical limitations encountered during genetic testing could prevent prediction of whether you will need a higher, lower or intermediate dose of warfarin.
Many factors affect how your body will respond to a medication. Non-genetic factors include interactions between different drugs you may be taking, other medical conditions you may have, and interactions between drugs and your lifestyle diet, exercise, smoking, alcohol consumption etc.
There are over 100 medications that, when taken with warfarin, can cause an increase in the effect of warfarin and may result in increased risk for bleeding. There are over 40 medications that, when taken with warfarin, can cause a decrease in the effect of warfarin and may result in an increased risk for blood clots.
For a list of medications that may affect your response to warfarin, click here. It is important that you talk to your healthcare providers about all of the medications both over-the-counter and prescription as well as supplements that you are taking, as they may interact with warfarin.
Do NOT make any changes to ANY medications without talking to your healthcare providers. The following foods are known to interact with warfarin: For a list of more foods, vitamins, and supplements that may affect your response to warfarin, click here.
How should I take Coumadin?
Lori Poulin, PharmDQ: Once the heart has been put back in rhythm, can you then discontinue the Coumadin therapy. The medical literature recommends Coumadin therapy for 4 weeks after cardioversion in some patients. Some people may need to take warfarin for an extended period of time, especially if they have other risk factors for clot formation.
Some risk factors include a history of coronary artery disease or stroke, recurring episodes of fibrillations, and other heart conditions. Coumadin inhibits the action of Vitamin K dependant blood clot formation.
It is important to maintain a consistent level of Vitamin K intake while taking Coumadin. Contact your physician immediately if you notice any signs of bleeding such as easy bruising, blood in your urine, black or bloody stools, nosebleeds, bleeding gums, or coughing up blood.
Coumadin can interact with many other medications.
What should I avoid while taking Coumadin?
Signs things you may see that may indicate more serious bleeding include pink or brown urine, red or black stools bowel movementscoughing up blood, or vomiting blood or "coffee ground" colored material. New symptoms changes in how you feel that may suggest serious bleeding is occurring include a severe headache, dizziness, fatigue or weakness.
If the "early warning" signs occur, you should contact your clinician immediately. If the indicators of more serious bleeding occur, you should secure medical attention immediately including going to an emergency department if necessary.
Numerous "drugs" including prescription medications, medications you can buy without a prescription, vitamins, dietary supplements, and herbal preparations can produce a dangerous change in the effect of warfarin. Therefore, it is very important that you keep your anticoagulation clinician up-to-date on any such product s you are taking. Additionally, you should not start, stop, or change the dosage of any such product without the approval of your anticoagulation clinician.
Coumadin side effects
Facebook Twitter My bookmarks. Syncope: an unusual presentation of acute pulmonary embolismdoubled the dose of Coumadin and asked the lab to draw another INR the next day. Feature Article Half received 162 mg of aspirin, and the other were given 81 mg of aspirin plus Coumadin. Aspirin therapyThe patient also discontinued diltiazem and Coumadin because he was very confused and anxious because he did not understand the nature of his disease. Occupational asthma with paroxysmal atrial fibrillation in a diamond polisher.
Grand Rounds in Environmental Medicine A From herbalist Jenny Boyes: Coumadin Warfarin works as an anticoagulant - it slows blood clotting and is used to treat high blood pressure by thinning the blood in the veins, thus easing pressure on the heart. Health Zone: What's up Doc. Point-of-care coagulation testing: stepping gently forwardLike Coumadin, it can be taken by mouth, but unlike Coumadin - which takes four days to work - Dabigatran acts within two hoursPromising Results of Drug Trial Could Herald a Replacement for Popular Blood ThinnerRichard Hays, a family practitioner who prescribes Coumadin for his patients diagnosed with atrial fibrillation.
Common Coumadin ide effects may include:
Do not change the amount of these foods in your diet without first talking to your doctor.
If you change your diet for any reason, such as due to illness or to lose weight, be sure to tell your doctor.
Be sure to inform your doctor and pharmacist of all the medications you take, including over-the-counter medications, vitamins, and herbal supplements, so they can monitor for drug interactions.
More frequent INR monitoring should be performed when starting or stopping other drugs, including botanicals, or when changing dosages of other drugs, including drugs intended for short-term use e.
The human body uses vitamin K in the blood clotting process. The VKORC1 gene codes for an enzyme that helps with the recycling of vitamin K. Genetic variation in VKORC1 can reduce the ability of this enzyme to recycle vitamin K.
Where can I get more information?
Revised: Sep 2016The following serious adverse reactions to COUMADIN are discussed in greater detail in other sections of the labeling:Drugs may interact with COUMADIN through pharmacodynamic or pharmacokinetic mechanisms.
Syncope: an unusual presentation of acute pulmonary embolismdoubled the dose of Coumadin and asked the lab to draw another INR the next day.