Generic Name: Clomid
What is Clomid?
After the correct dose has been determined, a patient may continue to take clomid until she becomes pregnant or for a total of six cycles. If a woman does not become pregnant after taking clomid for six cycles, the chances of further clomid treatment being successful is quite small. Some patients may require fewer or more cycles with clomid than others. Multiple pregnancy is probably the most talked-about risk associated with taking clomid. While there is an increased risk of multiple births associated with clomid, higher-order multiples are rare.
Approximately 8 percent of conceptions that occur with clomid are multiples with the vast majority being twins. Another risk of clomid is the formation of ovarian cysts.
Approximately 10 percent of women who undergo clomid treatment will develop an ovarian cyst. A pelvic examination may be performed at the end of the clomid treatment cycle to determine if an ovarian cyst has developed.
If an ovarian cyst is detected, clomid treatment may be discontinued for the following cycle.
Enclomiphene is the active part and makes up the remaining two thirds. It takes a long time for clomiphene to be cleared by the body. Because of this, clomiphene levels will increase in the blood over time if given over the course of a few months. Clomid works by blocking estrogen receptors in the hypothalamus and pituitary gland.
The result is that the pituitary gland is stimulated to produce more of the hormones that cause eggs to develop in the ovaries. These hormones are called gonadotropins and there are two important ones: FSH or follicle stimulating hormone and LH or luteinizing hormone. During clomid treatment, the levels of LH and FSH both increase. It is the FSH that is initially more important to get eggs to develop. Women with PCOS - polycystic ovary syndrome also do not ovulate as often with clomid. Increasing the dose of Clomid will increase the chances for ovulation to occur.
How should I take Clomid?
Clomiphene should not be taken, unless adequate monitoring is also performed simultaneously. It should also not be prescribed for more than 6 months. If it hasn't worked by then, you should move on to the next stage of treatment. Clomiphene is also commonly misused as "empiric " treatment - as a treatment to "enhance fertility" when the doctor cannot offer anything else.
However, while clomiphene may increase sperm counts in selected men, it hasn't been proven effective in increasing pregnancy rates.
What should I avoid while taking Clomid?
Some data suggest that zuclomiphene has greater estrogenic activity than enclomiphene. Clomiphene citrate has no apparent progestational, androgenic, or antiandrogenic effects and does not appear to interfere with pituitary-adrenal or pituitary-thyroid function. Based on early studies with 14C-labeled clomiphene citrate, the drug was shown to be readily absorbed orally in humans and excreted principally in the feces.
Some 14C label was still present in the feces 6 weeks after administration. Subsequent single-dose studies in normal volunteers showed that zuclomiphene cis has a longer half-life than enclomiphene trans.
Clomid side effects
If abnormal enlargement occurs Clomid should not be given until the ovaries have returned to pre-treatment size. Ovarian enlargement and cyst formation associated with Clomid therapy usually regress spontaneously within a few days or weeks after discontinuing treatment. Most of these patients should be managed conservatively.
Visual Symptoms: Patients should be advised that blurring or other visual symptoms such as spots or flashes scintillating scotomata may occasionally occur during or shortly after therapy with Clomid. The visual disturances may be irreversible, especially with increased dosage or duration of therapy See sections 4. Patients should be warned that visual symptoms may render such activities as driving a car or operating machinery more hazardous than usual, particularly under conditions of variable lighting.
Common Clomid ide effects may include:
This study shows that CC is a safe and efficacious drug to use as an alternative to exogenous testosterone.
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Cycle day 1, by definition, is the first day of full flow during the menstrual cycle.
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Clomid, Serophene, or clomiphene citrate generic name is a medication that is commonly used for the treatment of infertility.