Generic Name: Generic chloromycetin
What is Generic Chloromycetin?
Chloramphenicol succinate ester an intravenous prodrug form is readily excreted unchanged by the kidneys, more so than chloramphenicol base, and this is the major reason why levels of chloramphenicol in the blood are much lower when given intravenously than orally. Plasma levels should be monitored in all children under the age of four, the elderly, and patients with renal failure.
Manufacture of oral chloramphenicol in the U. No oral formulation of chloramphenicol is now available in the U. The intravenous IV preparation of chloramphenicol is the succinate ester, because pure chloramphenicol does not dissolve in water. It has the great advantage of requiring only a single injection, whereas ceftriaxone is traditionally given daily for five days. Isolated case reports of aplastic anaemia following use of chloramphenicol eyedrops exist, but the risk is estimated to be less than one in 224,716 prescriptions.
Although its use in veterinary medicine is highly restricted, chloramphenicol still has some important veterinary uses. Texas Medical Branch, Galveston.
He is a Clinical Professor retired in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.
A generally irreversible type of marrow depression leading to aplastic anemia with a high rate of mortality is characterized by the appearance weeks or months after therapy of bone marrow aplasia or hypoplasia. It was originally isolated from a species of.
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How should I take Generic Chloromycetin?
Chloramphenicol is not effective against infections caused by parasites intestinal wormsmites, viruses, or fungi. While generally safe and effective when prescribed by a veterinarian, chloramphenicol can cause side effects in some animals. Chloramphenicol should not be used in animals with known hypersensitivity or allergy to the drug. The most serious adverse effect in people is an irreversible suppression of the blood-forming cells aplastic anemia. For this reason, chloramphenicol exposure in humans should be limited as much as possible.
This reaction aplastic anemia is not possible in animals, however chloramphenicol may suppress the blood-forming cells in a reversible manner if administered for prolonged periods at high doses. In cats, for example, this reaction may be observed after two weeks of continuous treatment.
What should I avoid while taking Generic Chloromycetin?
Ethics approval James Cook University Ethics Committee, approved on 28th March 2007 ref: H2590 Study design Randomised, controlled, double-blinded trial. Primary study design Interventional Secondary study design Randomised controlled trial Trial setting Not specified Trial type Prevention Patient information sheet Condition Wound infection Intervention A single application of topical chloramphenicol ointment versus topical paraffin ointment following minor surgery.
Intervention type Other Phase Not Specified Drug names Primary outcome measures Infection. Participant type Patient Age group Not Specified Gender Both Target number of participants 948 474 in each group Participant exclusion criteria 1. PubMed Abstract Additional files Editorial Notes About Governance Why register. Chloromycetin is used in the treatment of infections caused by bacteria.
It is supplied as drops or ointments.
Generic Chloromycetin side effects
Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away. If you notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority. Some health conditions may make you more susceptible to the side-effects of the drug.
Common Generic Chloromycetin ide effects may include:
Chloramphenicol has been used to treat protozoa infections in animals.
Many medicines have not been studied specifically in older people.
Do not leave it on a windowsill or in the car.
Do not stop using your medicine or lower the dosage without checking with your doctor or pharmacist.
Intravenous chloramphenicol use has been associated with the so-called gray baby syndrome. UDP-glucuronyl transferaseso chloramphenicol remains unmetabolized in the body. The condition can be prevented by using the drug at the recommended doses, and monitoring blood levels.
No standard dose reduction exists for chloramphenicol in liver impairment, and the dose should be adjusted according to measured plasma concentrations.
More about Generic Chloromycetin
Other brands:Generic suhagra duralong
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Chloromycetin Thesaurus Definitions of Chloromycetin n an oral antibiotic trade name Chloromycetin used to treat serious infections especially typhoid fever Synonyms: chloramphenicol Type of: antibiotic, antibiotic drug a chemical substance derivable from a mold or bacterium that can kill microorganisms and cure bacterial infections Word Family Sign up, it's free.
Intravenous chloramphenicol use has been associated with the so-called gray baby syndrome.