Generic Name: Casodex
What is Casodex?
Testosterone is an androgen hormone produced by the testes and adrenal glands. Bicalutamide works by blocking testosterone receptors on the prostate cells, and therefore preventing testosterone from attaching to the receptors on the surface of the prostate cancer cells.
Without testosterone, the cancer cells may either grow more slowly, or stop growing altogether. Do not take two doses at the same time. Bicalutamide may be given in combination with other medications, such as LHRH agonists.
Store this medication at room temperature, in the original container. Bicalultamide is available through retail, mail order, and specialty pharmacies. This medication may be covered under your prescription drug plan. This medication may also be available at a low cost through Rx Outreach for those who meet financial qualifications. There are a number of things you can do to manage the side effects of bicalutamide.
Talk to your doctor or nurse about these recommendations.
I also asked him about TRT. He said he only gave that to patients with low energy levels, and that that was not me. I would also like to mention that without the support of my wife, I would have been lost. If family members are reading this, they must be aware that their man may go thru some very drastic changes, and the amouont of time that this lasts is unknown.
My wife just supported me in the way I wanted to be supported and did not interfere in any way with my problems. Her death is not about her. Her death is about those left living. It is about their spiritual growth and their lessons about how to stay in the love space and learn acceptance of whatever is, regardless of what has occurred.
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How should I take Casodex?
CASODEX bicalutamide has no indication for women, and should not be used in this population. CASODEX bicalutamide may cause fetal harm when administered to a pregnant woman. There are no studies in pregnant women using CASODEX bicalutamide. CASODEX bicalutamide is a non-steroidal androgen receptor inhibitor.
It competitively inhibits the action of androgens by binding to cytosol androgen receptors in the target tissue. When CASODEX bicalutamide is combined with luteinizing hormone releasing hormone LHRH analog therapy, the suppression of serum testosterone induced by the LHRH analog is not affected.
However, in clinical trials with CASODEX bicalutamide as a single agent for prostate cancer, rises in serum testosterone and estradiol have been noted.
What should I avoid while taking Casodex?
During the 10 years that he led the Oncology Clinical team, he was responsible for bringing a number of oncology products to market, including Zoladex, Casodex, Arimidex, Tomudex and Faslodex, as well as leading the Phase III program for the novel antipsychotic, Seroquel.
Celtic Pharma Appoints Two New Senior ExecutivesThe new treatment is a member of the antiandrogen family of drugs, called Casodex, which has been developed by AstraZeneca. Zacks Analyst Blog Highlights: AstraZeneca, Darden Restaurants, Inc. There are no Less than 280 Therapeutics Targeting Prostate Cancer TodayAs a result of market dominance by agents such as leuprolide, and AstraZeneca's Zoladex goserelin and Casodex bicalutamidethere is little space in the antihormonal therapies market for new competition unless significant clinical superiority or a unique selling point is demonstrated.
Major Gap in the Prostate Cancer Hormone-Refractory Market According to New Report Medical browser. Doe dit alleen in overleg met uw arts. De werkzame stof bicalutamide zit in de volgende producten: Casodex Bicalutamide Biluron Bicalutamide is sinds 1995 internationaal op de markt. Disclaimer Vind een apotheek Wilt u meer weten, of heeft u een vraag over uw eigen situatie.
Casodex side effects
This class of medicines can cause a short-term worsening of symptoms before the improvement begins, and bicalutamide can prevent this. Casodex tablets contain the active ingredient bicalutamide, which is a type of medicine known as an anti-androgen.
Prostate cancers are sensitive to testosterone and their growth is increased in the presence of this hormone. This is because testosterone binds to androgen receptors on the prostate cancer cells and causes changes within the cells that result in faster growth of the cancer.
Bicalutamide works by preventing testosterone from binding to the androgen receptors on the prostate cancer cells.
Common Casodex ide effects may include:
Whenever the action of testosterone is inhibited, side effects ensue.
Isoform 189 appeared upregulated in DU145 cells lane 2 compared to PC3 cells lane 1 and increased in LNCaP-R and UR cells after treatment with Casodex lanes 5 and 7, respectively.
However, in light of the survival findings from Trial 25, it is important to investigate whether these trends were also seen in the watchful waiting patients of Trial 24 there were no watchful waiting patients in Trial 23.
Renal Impairment Renal impairment as measured by creatinine clearance had no significant effect on the elimination of total bicalutamide or the active R-enantiomer.
The long-term effects of bicalutamide on male fertility have not been studied. Use of bicalutamide during breast-feeding is not indicated, and if excreted in milk, would be expected to have the potential for adverse effects in a nursing infant due to the anti-androgenic activity. Bicalutamide has been detected in rat milk. The liver extensively metabolizes bicalutamide, and limited data suggest that in subjects with moderate to severe hepatic disease, excretion could be delayed, leading to accumulation.
Rare cases of death or hospitalization due to severe hepatotoxicity have been reported with the clinical use of bicalutamide.
Where can I get more information?
Store this medication at room temperature, in the original container.
CASODEX bicalutamide should be used with caution in patients with moderate-to-severe hepatic impairment.