Generic Name: Cartia xt
What is Cartia Xt?
Bosentan: Although no specific interactions have been documented, bosentan has vasodilatory effects and may contribute additive hypotensive effects when given with calcium-channel blockers.
In addition, bosentan may induce hepatic metabolism of calcium-channel blockers metabolized by CYP3A4 isoenzymes. Diltiazem and verapamil have potential to inhibit CYP3A4 metabolism of bosentan. Bosentan has been shown to have no pharmacokinetic interactions with nimodipine.
Bosutinib: Avoid concomitant use of bosutinib and diltiazem as bosutinib plasma exposure may be significantly increased resulting in an increased risk of bosutinib adverse events e. Bosutinib is a CYP3A4 substrate and diltiazem is a moderate CYP3A4 inhibitor. In a cross-over trial in 18 healthy volunteers, the Cmax and AUC values of bosutinib were increased 1.
Bretylium: Concomitant use of bretylium with other antiarrhythmis, such as diltiazem, can have additive, antagonistic, or synergistic electrophysiologic, pharmacodynamic, or toxic effects, including hypotension. Combined antiarrhythmic therapy may necessitate a reduction in antiarrhythmic drug dosages, to decrease the potential for toxicity. Diltiazem is a moderate inhibitor of CYP3A4.
The Food and Drug Administration FDA approved Zocor as a brand-name drug because the manufacturing company demonstrated to the FDA that this drug had unique pharmacological and therapeutic characteristics. As a result, this drug was granted several patents and, for about 20 years, the manufacturing company had been the only company making and selling this drug.
The active ingredient of this drug is identified by the generic name simvastatin. The patent for the active ingredient simvastatin expired in July 2006 and, now, simvastatin is a generic drug. But, Zocor is and will always be called a brand-name drug. Examples of generic drugs: -- the generic drug Albuterol consists of the active ingredient albuterol and the manufacturing company has decided to market the drug using the generic name albuterol itself.
On the other hand, it is worth noting that Cardizem CD and Cartia XT are brand names, but Cardizem CD is a brand-name drug while Cartia XT is a generic drug. In fact, Cartia XT is the generic equivalent to Cardizem CD. The Food and Drug Administration FDA approved Cardizem CD as a brand-name drug and approved Cartia XT as a generic drug. Patent is the right to exclude others from making, using, or selling an invention or product.
Patents are granted and issued by the U. This member will no longer be able to contact or interact with you. You can't do that on your own profile. You have been blocked by this member.
How should I take Cartia Xt?
For high blood pressure:For oral dosage form extended-release capsules :Adults-At first, 180 to 240 milligrams mg once a day in the morning. For oral dosage form extended-release tablets :Adults-At first, 180 to 240 milligrams mg once a day, either in the morning or at bedtime.
Missed DoseTOP If you miss a dose of this medicine, take it as soon as possible. Keep out of the reach of children. For this medicine, the following should be considered: AllergiesTOP Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. PediatricTOP Appropriate studies have not been performed on the relationship of age to the effects of diltiazem in the pediatric population.
GeriatricTOP Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of diltiazem in the elderly.
What should I avoid while taking Cartia Xt?
The manufacturer of afatinib recommends permanent discontinuation of therapy for severe or intolerant adverse drug reactions at a dose of 20 mg per day, but does not address a minimum dose otherwise.
Aldesleukin, IL-2: Calcium channel blockers may potentiate the hypotension seen with aldesleukin, IL 2. Alemtuzumab: Alemtuzumab may cause hypotension. Careful monitoring of blood pressure and hypotensive symptoms is recommended especially in patients with ischemic heart disease and in patients on antihypertensive agents.
Alfentanil: Alfentanil may cause bradycardia. In addition to additive hypotensive effects, calcium-channel blockers that are CYP3A4 inhibitors e. Reduced clearance of alfentanil should be considered when recovery from alfentanil infusions for anesthesia is evaluated in patients receiving concurrent diltiazem therapy.
Alfuzosin is primarily metabolized by the CYP3A4 hepatic enzyme.
Cartia Xt side effects
Visit the FDA MedWatch website or call 1-800-FDA-1088. Diabetes and You Online Hearing Test Managing Diabetes Expert Orthopedic Care Monitor Glucose Spikes Treat Pet Anxiety Advanced Breast Cancer Care for Valve Disease.
Lowering Blood Pressure Exercise Tips Slideshow Pictures Brand Names: Cardizem, Cardizem CD, Cardizem LA, Cartia XT, Dilacor XR, Dilt-CD, Diltia XT, Diltiazem Hydrochloride CD, Diltiazem Hydrochloride SR, Diltiazem Hydrochloride XR, Diltiazem Hydrochloride XT, Dilt-XR, Diltzac, Taztia XT, Tiazac Generic Name: diltiazem Pronunciation: dil TYE a zem What is diltiazem Cardizem, Cardizem CD, Cardizem LA, Cartia XT, Dilacor XR, Dilt-CD, Diltia XT, Diltiazem Hydrochloride CD, Diltiazem Hydrochloride SR, Diltiazem Hydrochloride XR, Diltiazem Hydrochloride XT, Dilt-XR, Diltzac, Taztia XT, Tiazac.
What are the possible side effects of diltiazem. What should I discuss with my healthcare provider before taking diltiazem.
Common Cartia Xt ide effects may include:
It is not known whether diltiazem will harm an unborn baby.
Milnacipran: Milnacipran has been associated with an increase in blood pressure.
Guanfacine is primarily metabolized by CYP3A4, and diltiazem is a moderate CYP3A4 inhibitor.
During one in vitro study, coadministration with cyclosporine, a potent P-gp inhibitor, resulted in an 83-fold and 124-fold increase in the mean Cmax and AUC of rifaximin, respectively.
Diltiazem is partially a substrate of P-glycoprotein P-gp. Diltiazem is also a moderate CYP3A4 inhibitor. Vardenafil: Vardenafil is metabolized by hepatic cytochrome P450 3A4. Inhibitors of CYP3A4, such as diltiazem, can reduce vardenafil clearance.
More about Cartia Xt
Other brands:Generic claritin
Where can I get more information?
Increased concentrations of atorvastatin are associated with an increased risk of myopathy and rhabdomyolysis.
In patients with hepatic impairment, the effects of reduced metabolism and P-gp inhibition may further increase exposure to rifaximin.