Generic Name: Generic azulfidine
What is Generic Azulfidine?
People who have had an adverse reaction to other sulfa drugs ay also be sensitive to sulfasalazine. Sulfasalazine can interfere with the body's ability to absorb folic acid.
The prescribing physician may recommend folic acid supplements. The effect that sulfasalazine has on an unborn child has not been studied extensively. Sulfasalazine should only be used during pregnancy if clearly needed. Notify the prescribing doctor if you become pregnant while taking sulfasalazine.
Sulfasalazine does pass into breast milk, and could affect a nursing infant. National Center on Birth Defects and Developmental Disabilities.
Therefore, sulfasalazine is contraindicated in patients with sulfasalazine hypersensitivity, salicylate hypersensitivity, sulfonamide hypersensitivity, and 5-aminosalicylates hypersensitivity. Due to structural similarity to sulfonamides, patients with furosemide hypersensitivity, thiazide diuretic hypersensitivity, sulfonylurea hypersensitivity, or carbonic anhydrase inhibitor hypersensitivity should use sulfasalazine with caution. Deaths related to hypersensitivity reactions and irreversible neuromuscular and central nervous system changes have been reported following sulfasalazine treatment.
Only after careful consideration should sulfasalazine be used in a patient with hematological disease since sulfonamides are associated with blood dyscrasias. Sulfasalazine should be used with caution in patients with pre-existing folate deficiency megaloblastic anemia since it decreases folate absorption. Deaths related to agranulocytosis, aplastic anemia, and other blood dyscrasias have been reported following sulfasalazine treatment. Patients with G6PD deficiency should be monitored carefully during sulfasalazine therapy for signs of hemolytic anemia.
Only after careful consideration should sulfasalazine be used in a patient with hepatic disease since sulfonamides are metabolized in the liver and are rarely associated with severe hepatotoxicity. Deaths related to liver damage have been reported following sulfasalazine treatment.
Monitor for the onset of nausea, vomiting, abdominal pain, loss of appetite, diarrhea, or jaundice which may be signs of a serious liver disorder. Liver function tests LFTs should be done at baseline and then every other week during the first three months of therapy, monthly during the next 3 months, and thereafter, every 3 months or as clinically indicated. In patients with porphyria, sulfasalazine is contraindicated because sulfonamides can precipitate an acute attack.
Only after careful consideration should sulfasalazine be used in a patient with renal impairment or renal failure because the drug is excreted in the urine, and accumulation is associated with an increased risk of toxicity. Deaths related to renal damage have been reported following sulfasalazine treatment.
How should I take Generic Azulfidine?
I am interested in if it would be safe for me to take alcohol while am on azulfidine. As I have to take this medication for at least next 6 weeks I wonder if I can mix it with alcohol.
Although it would be better not to mix it. Azulfidine increases intoxicating effects of alcohol. I was on azulfidine because of ulcerative colitis, and it made me dizzy so I avoided alcohol at all during the therapy. Quick reply New Genetlic Links To Juvenile Idiopathic Arthritis Found We usually think of arthritis as a disease of the elderly, but juvenile idiopathic arthritis is one of the most common diseases of childhood.
What should I avoid while taking Generic Azulfidine?
Serious skin reactions, some of them fatal, including exfoliative dermatitis, Stevens-Johnson syndrome, and toxic epidermal necrolysis, have been reported in association with the use of sulfasalazine. Patients are at highest risk for these events early in therapy, with most events occurring within the first month of treatment. Sulfasalazine should be discontinued at the first appearance of skin rash, mucosal lesions, or any other sign of hypersensitivity.
Severe, life-threatening, systemic hypersensitivity reactions such as drug rash with eosinophilia and systemic symptoms have been reported in patients taking sulfasalazine. Adequate fluid intake must be maintained in order to prevent crystalluria and stone formation.
Patients with glucose-6 phosphate dehydrogenase deficiency should be observed closely for signs of hemolytic anemia. This reaction is frequently dose related. However, sulfasalazine showed equivocal mutagenic response in the micronucleus assay of mouse and rat bone marrow and mouse peripheral RBC and in the sister chromatid exchange, chromosomal aberration, and micronucleus assays in lymphocytes obtained from humans.
Generic Azulfidine side effects
A Enteric-coated or belly-coated planning is available that could reduce a number of the unwanted effects linked with Azulfidine, especially indigestion. The dose for some other circumstances, including ulcerative colitis, could vary. It normally takes between 1 and A COUPLE OF MONTHS months after beginning sulfasalazine to see any improvement in rheumatoid arthritis symptoms signs. Your email address will not be published. UsesGeneric Azulfidine was used more than 70 years past to treat rheumatoid arthritis symptoms.
DosageAzulfidine comes in a 500 milligram pill and needs to be used with a glass filled with water as well as food to prevent an upset belly. Leave a Reply Cancel replyYour email address will not be published.
Common Generic Azulfidine ide effects may include:
In the first three days of therapy you may increase the dosage according to this standard procedure:The instruction of the drug reports that when the symptoms subside, the patient is transferred to a maintenance dose of one tablet three or four times a day.
In some cases, it is advisable to initiate therapy with a smaller dosage, e.
There are reports with limited data of bloody stools or diarrhea in human milk fed infants of mothers taking sulfasalazine.
This information does not replace the advice of a doctor.
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Where can I get more information?
Marks, MD, is a board-certified internist and gastroenterologist.
Stop using sulfasalazine and call your doctor at once if you have any of these serious side effects:This is not a complete list of side effects and others may occur.