Aygestin

Generic Name: Aygestin

What is Aygestin?

Norethindrone and norethindrone acetate should be used cautiously in patients with a history of major depression, migraine, or seizure disorder. Use of hormonal contraceptive products in female children before menarche is not indicated. Barbiturates induce hepatic enzymes and can accelerate the rate of metabolism of hormones, including progestins.

For patients on hormone replacement treatments HRT with progestins, monitor for altered clinical response, such as increased hot flashes, vaginal dryness, changes in withdrawal bleeding, or other signs of decreased hormonal efficacy.

For women taking hormonal contraception for birth control, loss of efficacy may lead to breakthrough bleeding and an increased risk for pregnancy. Pregnancy has been reported during therapy with hormonal contraceptives in patients receiving barbiturates.

If used for contraception, an alternate or additional form of contraception should be considered in patients prescribed hepatic enzyme inducing drugs. The alternative or additional contraceptive agent may need to be continued for 1 month after discontinuation of the interacting medication. Acetohexamide: Progestins can impair glucose tolerance. Patients receiving antidiabetic agents should be closely monitored for signs indicating changes in diabetic control when therapy with progestins is instituted or discontinued.

Acitretin: Acitretin reduces the efficacy of oral progestin only contraceptives. Since Acitretin may cause serious birth defects, the patient should use 2 forms of reliable contraception at the same time for at least 1 month before beginning acitretin therapy, during acitretin therapy, and must continue to use them for at least 3 years after acitretin treatment has stopped.

Be sure to tell your doctor if you experience any irregular or unexplained vaginal bleeding while taking norethindrone. Norethindrone makes some women depressed. If you've suffered from serious depression in the past, alert your doctor if you think you're having a relapse.

You will probably need to stop taking norethindrone. The long-term effects of drugs such as norethindrone on the function of certain organs--including the pituitary, ovaries, adrenal glands, liver, and uterus--are unknown.

Norethindrone may affect cholesterol and blood-sugar levels. If you have diabetes or high cholesterol, your doctor will want to watch you closely while you are taking norethindrone.

Norethindrone may mask the onset of menopause. However, women who are of menopausal age are still eligible to take the drug. If you're being screened for cancer, make sure the doctor or lab technician knows you are taking norethindrone.

How should I take Aygestin?

Absorption of micronized progesterone is enhanced twofold when the hormone is taken with food. Transvaginal progesterone delivery is the most practical nonoral route of administration. A new progesterone vaginal gel Crinone has sustained-release properties that were not available in the original intravaginal preparations. Intravaginal administration produces uterine effects with minimal systemic side effects. The pharmacologic effects of synthetic progestins differ from those of natural progesterone.

Reported androgenic effects of synthetic progestins include fluid retention, reduction of HDL cholesterol levels, headaches and mood disturbance.

What should I avoid while taking Aygestin?

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Forum RulesHi everybody, Its been about 3 years since I posted on here, trying to loose weight, and I am not sure what the new updates are to the whole diets that work, I do know they are all mixed.

I was given aygestin to stop bleeding.

Aygestin side effects

There is no indication for AYGESTIN in pregnancy. Undiagnosed vaginal bleeding Known, suspected or history of cancer of the breast Active deep vein thrombosis, pulmonary embolism or history of these conditions Active or recent e. Pharmacokinetics Absorption Norethindrone acetate is completely and rapidly deacetylated to norethindrone NET after oral administration, and the disposition of norethindrone acetate is indistinguishable from that of orally administered norethindrone.

Metabolism Norethindrone undergoes extensive biotransformation, primarily via reduction, followed by sulfate and glucuronide conjugation.

Excretion Plasma clearance value for norethindrone is approximately 0. Special Populations Geriatrics The effect of age on the pharmacokinetics of norethindrone after AYGESTIN administration has not been evaluated.

Race The effect of race on the disposition of norethindrone after AYGESTIN administration has not been evaluated.

Common Aygestin ide effects may include:

  • Monitor for decreased efficacy of morphine.

  • Tigecycline: It would be prudent to recommend alternative or additional contraception when oral contraceptives OCs are used in conjunction with antibiotics.

  • Hematologic: eosinophilia, agranulocytosis, thrombocytopenia, leukopenia, granulocytopenia, G6PD deficiency anemia, hemolytic anemia, megaloblastic anemiaRespiratory: asthma attacks, pulmonary hypersensitivity reactions including diffuse interstitial pneumonias with prolonged therapy Skin: rash, exfoliative dermatitis, alopecia, pruritus, urticaria, angioedema, photosensitivity, Stevens-Johnson syndromeOther: drug fever, chills, superinfection limited to urinary tracthypersensitivity reactions including anaphylaxis, lupus-like syndromeUricosurics such as probenecid : decreased renal clearance and increased blood level of nitrofurantoinDrug-diagnostic tests.

  • If you have an allergy to peanuts, make sure your doctor knows this before you take this brand of progestin.

Have any of you ladies ever taken Aygestin or heard of it being used for peri. When the cyst dissolved, I went off all forms of hormones-I got my period in May, and then in June, all hell broke loose.

My doctor recommended that I go back on bcp, which I did this month, and I'm happy to report that I'm feeling better. I do think the aygestin helped me, but I just didn't realize it at the time. The only thing I didn't like about it was that it caused me to feel very bloated.

Where can I get more information?

  • Serum lipoproteins HDL and LDL should be monitored during therapy with norethindrone.

  • Saquinavir: Saquinavir may increase oral contraceptive metabolism by stimulation of CYP3A4 metabolism.