Generic Name: Arjuna
What is Arjuna?
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Know what to watch for and get tips for reducing your risks while taking this drug. Advertisement Side effects that you should report to your doctor or health care professional as soon as possible:allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tonguebreathing problemsburning, numbness, or tinglingchanges in visionconfused, restlessdiscolored, sore mouthfeverirregular heart beat, blood pressureseizurestremor, trouble walkingunusual bleeding or bruisingunusually weak or tired Side effects that usually do not require medical attention report to your doctor or health care professional if they continue or are bothersome :changes in tasteconstipation or diarrheadizzyheadachenausea, vomitingstomach upsettrouble sleepingvaginal itch, irritation Do not take this medicine with any of the following medications:bupropioncertain medicines for depression, anxiety, or psychotic disturbancesdoxepinfluoxetinefurazolidone John's worttryptophan This medicine may also interact with the following medications:birth control pillsmedicines for allergies or colds like phenylpropanolamine, pseudoephedrinemedicines for blood pressurestimulant medicines for attention disorders, weight loss, or to stay awake Disclaimer: Our goal is to provide you with the most relevant and current information.
However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.
Take this medicine by mouth with a glass of water. What should I tell my health care provider before I take this medicine.
Clinical trialsThe safety and effectiveness of linezolid when administered for periods longer than 28 days have not been established. Controlled clinical trials did not include patients with diabetic foot lesions, decubitus or ischaemic lesions, severe burns or gangrene. Therefore, experience in the use of linezolid in the treatment of these conditions is limited. There are very limited data from drug interaction studies and on the safety of linezolid when administered to patients on concomitant medications that might put them at risk from MAO inhibition.
Potential interactions producing elevation of blood pressureIn normotensive healthy volunteers, linezolid enhanced the increases in blood pressure caused by pseudoephedrine and phenylpropanolamine hydrochloride. Co-administration of linezolid with either pseudoephedrine or phenylpropanolamine resulted in mean increases in systolic blood pressure of the order of 30-40 mmHg, compared with 11-15 mmHg increases with linezolid alone, 14-18 mmHg with either pseudoephedrine or phenylpropanolamine alone and 8-11 mmHg with placebo.
Similar studies in hypertensive subjects have not been conducted. It is recommended that doses of drugs with a vasopressive action, including dopaminergic agents, should be carefully titrated to achieve the desired response when co-administered with linezolid.
Potential serotonergic interactionsThe potential drug-drug interaction with dextromethorphan was studied in healthy volunteers. Subjects were administered dextromethorphan two 20 mg doses given 4 hours apart with or without linezolid. No serotonin syndrome effects confusion, delirium, restlessness, tremors, blushing, diaphoresis and hyperpyrexia have been observed in normal subjects receiving linezolid and dextromethorphan.
Post marketing experience: there has been one report of a patient experiencing serotonin syndrome-like effects while taking linezolid and dextromethorphan which resolved on discontinuation of both medications.
How should I take Arjuna?
ZYVOX for ORAL SUSPZYVOX I. Register below for a customized experience and free access to premium resources. Bacterial infections Indications for ZYVOX: Susceptible vancomycin-resistant E.
You should confirm the information on the PDR. Register Now Email or Username Password Remember me Forgot your password. Drug information provided by: MicromedexLinezolid is used to treat certain bacterial infections in many different parts of the body, including certain types of skin infections or pneumonia.
Linezolid belongs to the family of medicines called antibiotics. It works by killing bacteria or preventing their growth.
What should I avoid while taking Arjuna?
While you are using this medicine, avoid taking an "SSRI" antidepressant without telling your doctor. Taking an SSRI antidepressant together with this medicine can cause symptoms such as anxiety, high fever, sweating, chills or goosebumps, memory problems, trouble concentrating, loss of coordination, or muscle spasms.
Eating tyramine while you are using this medicine can raise your blood pressure to dangerous levels. This is because Generic Zyvox Linezolid tablets may react with a substance which is naturally present in these foods.
Some people have developed a life-threatening condition called lactic acidosis while taking Linezolid tablets. There are no adequate and well-controlled studies conducted in pregnant women undergoing treatment with Linezolid. Linezolid tablets should be used during pregnancy only if the potential benefit justifies the potential risk to the foetus.
This medicine may be harmful to an unborn baby.
Arjuna side effects
I read that zyvox has very little influence on the CYP enzymes, so what is the DI. Doctor M, Dec 29, 2006 3 2,084 36 I know that tyramine is a chemical that cause severe reacations with zyvox, but what is the problem with fentanyl. Close monitoring is recommended for signs and symptoms of excessive serotonergic activity such as CNS irritability, altered consciousness, confusion, myoclonus, ataxia, abdominal cramping, hyperpyrexia, shivering, pupillary dilation, diaphoresis, hypertension, and tachycardia.
Particular caution is advised when increasing the dosages of these agents. The potential risk of serotonin syndrome should be considered even when administering one serotonergic agent following discontinuation of another, as some agents may demonstrate a prolonged elimination half-life.
The US manufacturers of fentanyl lozenges 7 and patches 8 state that use in patients who have received an MAOI in the previous 14 days is not recommended.
Common Arjuna ide effects may include:
Because Zyvox is a brand-name drug, it can be very expensive.
Never give it to other people even if their condition appears to be the same as yours.
Editors do not have any significant financial relationships with the industry that would introduce bias in the editing or review of database content.
However, given the severe underlying illness in the patient population, no causality could be established.
It is not detectably metabolized by human cytochrome P450 and it does not inhibit the activities of clinically significant human CYP isoforms 1A2, 2C9, 2C19, 2D6, 2E1, 3A4. The interaction studies conducted in normotensive subjects evaluated the blood pressure and heart rate effects of placebo, PPA or PSE alone, linezolid alone, and the combination of steady-state linezolid 600 mg q12h for 3 days with two doses of PPA 25 mg or PSE 60 mg given 4 hours apart.
Linezolid is a synthetic antibacterial agent of a new class of antibiotics, the oxazolidinones, which has clinical utility in the treatment of infections caused by aerobic Gram-positive bacteria. Linezolid binds to a site on the bacterial 23S ribosomal RNA of the 50S subunit and prevents the formation of a functional 70S initiation complex, which is an essential component of the bacterial translation process.
For streptococci, linezolid was found to be bactericidal for the majority of strains.
Where can I get more information?
CASES HAVE BEEN REPORTED SHORTLY AFTER INITIAL USE AS WELL AS AFTER SEVERAL YEARS OF USE.
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