Generic Name: Order arimidex
What is Order Arimidex?
SAN ANTONIO -- Should anastrozole Arimidex be the top choice in pharmacologic primary prevention of breast cancer, based on IBIS-II trial results presented here. No, said most experts. Even that was "quite a strong statement," commented session moderator Fabrice Andre, MD, PhD, of Institut Gustave Roussy in Villejuif, France. Kent Osborne, MD, told MedPage Today. And in primary prevention specifically, the risk reduction with anastrozole was on par with what was seen with fellow aromatase inhibitor exemestane Aromasin in the MAP.
Those results with those aromatase inhibitors have been stronger than reported with the selective estrogen receptor modulators SERMs tamoxifen and raloxifene Evistabut there are other factors to consider, namely side effect profiles, Osborne pointed out. Other side effects have been a concern with this class, particularly joint pain, bone loss, and vaginal symptoms.
But "most of these in uncontrolled situations are attributed to the drug. It's clear now that most of these aches and pains have nothing to do with aromatase inhibitors.
Further Information see less Arimidex general information What is Arimidex used for. Arimidex tablets 1mg are used to treat breast cancer in postmenopausal women, as first line therapy for early, advanced or metastatic breast cancer. Arimidex tablets 1mg are also used as additional treatment for early breast cancer in conjunction with other breast cancer treatment tamoxifen or if tamoxifen therapy has not helped prevent progression of the tumour.
Arimidex tablets 1mg contain anastrozole, which is a potent and highly selective inhibitor of aromatase, an enzyme that is involved in the biosynthesis of the female hormone oestrogen. In premenopausal women the primary source of oestrogen production are the ovaries and oestrogen is involved in producing secondary sexual characteristics, such as breast development and in regulating the menstrual cycle.
In postmenopausal women, when oestrogen production by the ovaries ceases, low levels of oestrogen are made in peripheral tissues, such as fat cells throughout the body, also some breast cancer cells, by conversion of androstenedione produced by the adrenal glands to estrone, due to the action of aromatase and then by further conversion to oestradiol the most active form of circulating oestrogen.
Anastrozole in Arimidex tablets 1mg blocks the action of aromatase, preventing the formation of oestrogen and helping to prevent growth of oestrogen-dependent breast tumours. What does Arimidex contain. Arimidex tablets contain the active ingredient anastrozole1 mgan aromatase inhibitor that blocks oestrogen biosynthesis and is used to treat breast cancer.
They also contain lactose, povidone, sodium starch glycollate, magnesium stearate, hypromellose, macrogol 300, titanium dioxide Treating breast cancer with ArimidexArimidex tablets 1mg are used to treat breast cancer in postmenopausal women.
They contain anastrozole, which blocks the action of aromatase an enzyme involved in the biosynthesis of the female hormone oestrogen, in peripheral tissues, such as fat cells and also by some breast cancer cells. Arimidex tablets 1mg are used as first-line therapy for early, advanced or metastatic breast cancer, also in conjunction with other breast cancer treatment tamoxifen or if tamoxifen therapy has not helped prevent progression of the tumour.
What are the side effects of Arimidex. The most commonly reported side effects when taking Arimidex include: hot flushes, joint pain or stiffness, skin rash gastrointestinal upset nausea, vomiting, diarrhoeaheadache, feeling weak astheniavaginal dryness and bleeding, carpal tunnel syndrome, sleepiness, hair loss, anorexiaWhen should Arimidex not be used.
You should not use Arimidex tablets 1mg if you:are allergic to anastrozole or any ingredients in Arimidexare premenopausal, pregnant or breastfeedinghave kidney or liver diseaseare taking medicines that interact with Arimidex including: oestrogen containing medication, tamoxifen, another breast cancer drugHow should Arimidex be taken.
How should I take Order Arimidex?
Food reduces the rate but not the overall extent of anastrozole absorption. The pharmacokinetics of anastrozole are linear over the dose range of 1 to 20 mg, and do not change with repeated dosing. The pharmacokinetics of anastrozole were similar in patients and healthy volunteers. Steady-state plasma levels are approximately 3-to 4-fold higher than levels observed after a single dose of ARIMIDEX. Plasma concentrations approach steady-state levels at about 7 days of once daily dosing.
Metabolism of anastrozole occurs by N-dealkylation, hydroxylation and glucuronidation. Three metabolites of anastrozole triazole, a glucuronide conjugate of hydroxy-anastrozole, and a glucuronide conjugate of anastrozole itself have been identified in human plasma and urine. The mean elimination half-life of anastrozole is 50 hours.
What should I avoid while taking Order Arimidex?
ARIMIDEX helps to control your condition, but does not cure it. Therefore you must take ARIMIDEX every day. Do not stop taking it unless your doctor tells you to - even if you feel better. Immediately telephone your doctor or the Poisons Information Centre telephone 13 11 26 for advice, or go to Accident and Emergency at the nearest hospital if you think that you or anyone else may have taken too much ARIMIDEX.
Do this even if there are no signs of discomfort or poisoning.
Order Arimidex side effects
It is a resource for women who have been diagnosed with breast cancer, a place for loved ones to gain a better understanding of the disease, and a tool for doctors to share information. Beyond The Shock is a collaborative breast cancer guide created by the National Breast Cancer Foundation, Inc. NBCF with the support of the finest medical experts, doctors, and researchers in the world.
NBCF utilized ground-breaking technology and the resources of the global medical community to create an accessible platform for understanding a diagnosis of breast cancer. Not sure I want to take. Tumor size 4mm stage 1, invasive ductal. You are also lucky to have this type of breast cancer. Plenty of women on this board so not have this option as they don't have the type of cancer that would benefit from this type of treatment.
Common Order Arimidex ide effects may include:
See the end of this leaflet for a complete list of ingredients in ARIMIDEX.
Quote Reply Share elle0 Add As Friend Private Reply Report Abuse Stop Tracking Track Thread Email Friend RE: Side Effects of Arimidex by elle0 on Sun Feb 03, 2008 12:00 AM Quote Reply HiI'm new to this site as well and am a 2x survivor.
Legal Notices Site Map Contact Us Social navigation Facebook Twitter.
Inhibition of aromatase reduces the production of estrogen.
The generic product, anastrozole, must demonstrate that it is bioequivalent before it is approved by the FDA for the treatment of cancer. Once approved, it is considered to be the same as the brand name product, Arimidex.
Generic drugs are lower-cost alternatives to more expensive brand-name drugs. They will appear different and have a few other minor differences from the brand-name drugs, but their labeling and directions for use must be virtually the same as that of the brand name product. Both brand-name and generic drug manufacturing facilities must follow the same standards of good manufacturing practices and meet the U.
Where can I get more information?
Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise.
Estrogen and progesterone positive.