Generic Name: Arcoxia
What is Arcoxia?
Merck sells Arcoxia in 63 countries, and the company underwrote an extensive safety testing program that involved 34,000 arthritis patients.
The studies showed that Arcoxia caused nearly three times as many heart attacks, strokes and deaths as naproxen, a popular pain pill sold as Aleve, but was no more effective in curing pain. Patients taking Arcoxia suffered worrisome increases in blood pressure. Representatives of his company who followed him said Arcoxia was no more effective than 20 older pain pills already marketed - some for pennies a pill - and just as risky for the heart than all but one of them.
It was a tepid endorsement for a medicine Merck had once hoped would offer arthritis sufferers significantly better and safer pain relief. Indeed, Merck executives insisted for years that the company would seek to sell only medicines that offered substantial benefits over previous therapies.
David Felson, a panel member from Boston University. Felson said the testing of Arcoxia and similar medicines should be stopped until companies could create drugs with fewer heart risks. Other panelists said patients needed better arthritis drugs, not more of them.
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Additional Gastrointestinal Safety Data In two 12-week double-blind endoscopy studies, the cumulative incidence of gastroduodenal ulceration was significantly lower in patients treated with etoricoxib 120 mg once daily than in patients treated with either naproxen 500 mg twice daily or ibuprofen 800 mg three times daily.
Absorption Orally administered etoricoxib is well absorbed. Characteristics in patients Elderly patients: Pharmacokinetics in the elderly 65 years of age and older are similar to those in the young. In preclinical studies, etoricoxib has been demonstrated not to be genotoxic. Core: Calcium hydrogen phosphate anhydrous Croscarmellose sodium Magnesium stearate Microcrystalline cellulose Tablet coating: Carnauba wax Lactose monohydrate Hypromellose Titanium dioxide E171 Triacetin The 30- 60- and 120-mg tablets also contain indigo carmine lake E132 and yellow ferric oxide E172.
It is related to other anti-inflammatory medicines such as aspirin and ibuprofen, and it is thought to be less likely to give you stomach upsets than some other anti-inflammatories.
However, it is not free of side effects and this is why it is only available on prescription. Please ensure you have fully read the enclosed leaflet before starting your course of Arcoxia tablets. Arcoxia is available in strengths of 30mg, 60mg, 90mg, and 120mg of etoricoxib per tablet.
The effects are relatively long-lasting, so you only need to take one tablet each day. You should take the lowest strength that helps to relieve your symptoms, for the shortest duration of time necessary.
How should I take Arcoxia?
BreastfeedingIt is not known whether etoricoxib is excreted in human milk. Etoricoxib is excreted in the milk of lactating rats. Women who use etoricoxib must not breast feed see sections 4. Fertility The use of etoricoxib, as with any drug substance known to inhibit COX-2, is not recommended in women attempting to conceive.
In clinical studies, the undesirable effects profile was similar in patients with OA or RA treated with etoricoxib for one year or longer. In a clinical study for acute gouty arthritis, patients were treated with etoricoxib 120 mg once daily for eight days.
What should I avoid while taking Arcoxia?
Start ConsultationThere are certain situations where Arcoxia, should be used with caution or would not be recommended - this is common across most medicines. Arcoxia may not be suitable for patients under 16 or over 65, smokers or those with a peptic ulcer or any other bleeding in their gut. Those who have had a reaction in the past to aspirin or other anti-inflammatories, or suffer from heart disease or heart failure should also be aware this treatment might not be for them.
Other conditions for which Arcoxia is not recommend includean uncontrolled high blood pressure, diabetes, high levels of lipids fats in the blood, liver or kidney problems, and inflammatory bowel disease. If you are taking any other medication - either that which you have bought from a pharmacy or chemist, or that your doctor has prescribed - please raise this during your consultation.
Taking Arcoxia can potentially cause issues when mixed with other treatments, including aspirin, any other anti-inflammatory medicines, warfarin and other anti-coagulants. Lithium and medicines for heart and circulation conditions including high blood pressure can also cause problems when taken alongside Arcoxia.
Arcoxia side effects
Do not use this medicine after the expiry date which is stated on the carton. Contents of the pack and other information What ARCOXIA contains The active substance is etoricoxib. Each film coated tablet contains 30, 60, 90 or 120 mg of etoricoxib. Estos efectos son generalmente reversibles. Aspirina: Arcoxia se puede emplear concomitantemente con dosis bajas de aspirina empleadas como profilaxis cardiovascular.
Anticonceptivos orales: Arcoxia 60mg administrado concomitantemente con anticonceptivos orales que contienen 35 mcg de etinilestradiol EE y 0. Presentaciones: Envase conteniendo 7 comprimidos recubiertos.
Common Arcoxia ide effects may include:
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Neuropathic pain, or pain caused by abnormal activity of sensory neurons, remains undertreated.
Your doctor will prescribe Arcoxia for you only after you have used other medicines for your condition and they have not been suitable for you.
I think it's like any other dietary supplement.
Arcoxia may interact with certain medicines. For more information, see the package leaflet. Do not use Arcoxia if you are pregnant, planning to conceive or breastfeeding.
Where can I get more information?
GeneralIf during treatment, patients deteriorate in any of the organ system functions described above, appropriate measures should be taken and discontinuation of etoricoxib therapy should be considered.
Doses greater than those recommended for each condition have either not demonstrated additional efficacy or have not been studied.