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Symptoms associated with severe nifedipine overdosage include loss of consciousness, drop in blood pressure, heart rhythm disturbances, metabolic acidosis, hypoxia, cardiogenic shock with pulmonary edema. Additional liquid or volume must be administered with caution because of the risk of fluid overload.
Clearance of nifedipine would be expected to be prolonged in patients with impaired liver function. There has been one reported case of massive overdosage with tablets of another extended release formulation of nifedipine. Nifedipine selectively inhibits calcium ion influx across the cell membrane of vascular smooth muscle and cardiac muscle without altering serum calcium concentrations. The mechanism by which nifedipine reduces arterial blood pressure involves peripheral arterial vasodilatation and, consequently, a reduction in peripheral vascular resistance.
The increased peripheral vascular resistance, an underlying cause of hypertension, results from an increase in active tension in the vascular smooth muscle. Studies have demonstrated that the increase in active tension reflects an increase in cytosolic free calcium.
In the XI Plan, this mechanism of Lok Adalats has been made an indispensable part of the adjudication system. Industial Tribunal Cum Labour Courts RTI Manual under RTI Act, 2005 Introduction Incumbency position in CGITs Lok Adalat Recruitment Rules Guidelines for Outsourcing of manpower in CGITs Orders, Circulars and Instructions related to CGITs Lok Adalat Lok Adalat With due concern to the continuously rising number of industrial disputes, Lok Adalats have been introduced as an alternative grievance redressal mechanism, within the adjudication system of the CGITs from the 10th Five Year Plan.
Nifedipine immediate-release capsules are available as the brand-name drug Procardia. The capsules are used to treat angina chest pain. The tablets are used to treat either high blood pressure or angina. Nifedipine is used to lower blood pressure in people with hypertension. The drug form used depends on the condition it is treating. Talk to your doctor about which form is right for you. Nifedipine may be used as part of a combination therapy. This means you may need to take it with other medications.
If you are using it to treat high blood pressure, you may take it with other drugs that lower blood pressure. If you are using it to treat angina, you may take it with nitrates nitroglycerin products or beta-blockers.
Nifedipine belongs to a class of drugs called calcium channel blockers. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.
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The muscle that pumps blood received from veins into arteries throughout the body. See a picture of the Heart and learn more about the health topic. Heart rhythm disorders vary from minor palpitations, premature atrial contractions PACspremature ventricular contractions PVCssinus tachycardia, and sinus brachycardia, to abnormal heart rhythms such as tachycardia, ventricular fibrillation, ventricular flutter, atrial fibrillation, atrial flutter, paroxysmal supraventricular tachycardia PSVTWolf-Parkinson-White syndrome, brachycardia, or heart blocks.
Treatment is dependent upon the type of heart rhythm disorder. Genetic factors, high salt intake, and increased arterial stiffness cause high blood pressure. Dizziness, headache, nausea, and shortness of breath are just a few symptoms of high blood pressure. Untreated high blood pressure increases the risk of heart disease, kidney disease, atherosclerosis, eye damage, stroke, and increased risk of aneurysms.
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Serious side effects If you notice: Severe, sudden generalised allergic reaction including very rarely life-threatening shock e. Less serious side effects Apart from the side effects listed above, these are the other side effects of Adalat LA, starting with the more common ones: Common side effects These may affect up to 1 in 10 people headache flushing general feeling of being unwell constipation swelling, particularly of the ankles and legs Uncommon side effects These may affect up to 1 in 100 people stomach pain abdominal pain unspecific pain chills low blood pressure when standing up symptoms include fainting, dizziness, light headedness, occasional palpitations, blurred vision and sometimes confusion fainting irregular heartbeat palpitations dry mouth indigestion or upset stomach wind flatulence feeling sick nausea muscle cramps joint swelling sleep disorders anxiety or nervousness reddening ence blurred vision temporary increase in certain liver enzymes Rare side effects These may affect up to 1 in 1,000 people pins and needles inflammation of the gums, tender or swollen gums, bleeding gums Other side effects Frequency not known: frequency cannot be estimated from the available data stomach pain or distress caused by a mass of foreign material found in the stomach which may require surgery for removal difficulty swallowing abdominal pain, caused by obstruction of the gut or ulcers in the gut vomiting a reduction in the number of white blood cells leucopenia a more severe decrease in a specific class of white blood cell agranulocytosis increased blood sugar hyperglycaemia decreased skin sensitivity hypoaesthesia drowsiness somnolence eye pain chest pain angina pectoris heartburn or indigestion gastroesophageal sphincter insufficiency yellowing of the whites of the eyes or skin jaundice sensitivity to light photosensitivity allergic reaction small, raised areas of bleeding in the skin palpable pur pura joint pain muscle pain All of these symptoms usually go away when treatment with Adalat LA is stopped.
Reporting of side effects If you get any side effects, talk to your doctor or pharmacist. United Kingdom Yellow Card SchemeWebsite: www. How to store Adalat LA Keep this medicine out of the sight and reach of children. Contents of the pack and other information What Adalat LA contains Adalat LA tablets contain the active ingredient, nifedipine.
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Cases suitable for Lok Adalat Lok Adalats have competence to deal with a number of cases like: Compoundable civil, revenue and criminal cases Motor accident compensation claims cases Partition Claims Damages Cases Matrimonial and family disputes Mutation of lands case.
Section 19 5 of the legal Services Authorities Act, 1987 lays down the jurisdiction of the Lok Adalat which has the power to settle the dispute for cases which are pending, or such matters which are falling within the jurisdiction of and are not brought before any court for which the Lok Adalat is organised.
The Lok Adalat can take cognizance of those cases where the parties mutually agree to bring the matter to the Lok Adalat or where one party by moving an application to the Court seeks it permission for referring the case to the Lok Adalat.
The approach of the judges of the Lok Adalat is based in the principles of justice,equity and fair play and commonsense.
Checchi began implementing the five-year Afghanistan Assistance for the Development of Afghan Legal Access and Transparency ADALAT project in April 2016.
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Pioglitazone: Co-administration of pioglitazone for 7 days with 30 mg nifedipine ER administered orally q.
The judgment adopted by the ECJ on 6 January 2004 definitely sets that no infringement of Article 81 occurred.
ADALAT should be used with caution in patients with a poor cardiac reserve.
Do not stop taking this medication without consulting your doctor.
Calcium Channel Blockers Diltiazem: Pre-treatment of healthy volunteers with 30 mg or 90 mg t. ACE Inhibitors Benazepril: In healthy volunteers receiving single dose of 20 mg nifedipine ER and benazepril 10 mg, the plasma concentrations of benazeprilat and nifedipine in the presence and absence of each other were not statistically significantly different. Angiotensin-II Blockers Irbesartan: In vitro studies show significant inhibition of the formation of oxidized irbesartan metabolites by nifedipine.
Beta-blockers Adalat CC was well tolerated when administered in combination with beta-blockers in 187 hypertensive patients in a placebo-controlled clinical trial.
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Doctors have also treated Raynaud's syndrome with this medicine.
Welcome to West Bengal State Legal Services Authority Toggle navigation Home Source Objective Entitlement Gallery Publications Contact Us Alt Tag Alt Tag Alt Tag Alt Tag Alt Tag Alt Tag Lok Adalats The system of Lok Adalat or Nyayalaya was introduced in 1984 for the speedy settlement of cases and to reduce the burden of the regular courts, which now have a staggering backlog of nearly 24 million cases.