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You may need different amounts of your medicines, or you may need to take different medicines. Your doctor or pharmacist has more information on medicines to be careful with or to avoid while taking this medicine.
Follow all directions given to you by your doctor or pharmacist carefully. They may differ from the information contained in this leaflet. If you do not understand the instructions on the carton, ask your doctor or pharmacist for help.
Your doctor will tell you how many ACTOS tablets you should take. The dose your doctor will prescribe for you will usually be in the range of 15 mg to 45 mg per day.
You may need urgent medical attention. It is important that you remember to take ACTOS daily and at the dose prescribed by your doctor. If you are about to be started on any new medicine, remind your doctor and pharmacist that you are taking ACTOS. If you are going to have surgery, tell the surgeon or anaesthetist that you are taking this medicine.
Talk with your healthcare provider about possible risks. Actos may increase the risk of certain heart problems, particularly congestive heart failure. Avoid letting your blood sugar drop too low hypoglycemia. Low blood sugar can happen if you exercise too long, skip a meal, are under stress, or drink alcohol.
Actos may increase your risk of bone fractures in the hand, foot, or upper arm, especially in women. Discuss with your doctor the possible risks. Janumet is a name brand oral medication that contains a combination of the two generic medications metformin and sitagliptin and is used to control blood sugar levels.
Victoza is the brand name for the generic drug Liraglutide used as part of a complete treatment and prevention plan for patients with type 2 diabetes. Lantus is a brand name medication marketed by Sanofi-Aventis consisting of insulin glargine.
This is a prescription diabetes medication, and it is a long-acting form of insulin. It was originally approved for use by the Food and Drug Administration FDA in 1999. Combined with diet and exercise, it was believed that Actos could help patients with Type II Diabetes better control and manage their condition.
One of the most dangerous side effects of this medication is that Actos has been closely linked to an increased risk of bladder cancer in patients.
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The overall incidence and types of adverse events reported in placebo-controlled clinical trials of ACTOS monotherapy at doses of 7. For most clinical adverse events the incidence was similar for groups treated with ACTOS monotherapy and those treated in combination with sulfonylureas, metformin, and insulin. There was an increase in the occurrence of edema in the patients treated with ACTOS and insulin compared to insulin alone. Seven of these 10 patients received diuretics to treat these symptoms.
This was not reported in the insulin plus placebo group. The incidence of withdrawals from placebo-controlled clinical trials due to an adverse event other than hyperglycemia was similar for patients treated with placebo 2. In combination therapy studies with insulin, edema was reported in 15.
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Tell your doctor about all the medicines you take including prescription and over the counter medicines, vitamins, and herbal supplements. ACTOS and some of your other medicines can affect each other. You may need to have your dose of ACTOS or certain other medicines changed. Know the medicines you take. Keep a list of your medicines and show it to your doctor and pharmacist before you start a new medicine. They will tell you if it is okay to take ACTOS with other medicines.
What are the possible side effects of ACTOS. ACTOS may cause serious side effects including:Tell your doctor if you have any side effect that bothers you or that does not go away.
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As a consequence of enhancing insulin action, pioglitazone treatment in patients with polycystic ovarian syndrome may result in resumption of ovulation.
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Symptomatic and general supportive measures should be taken in case of overdose.
Other possible side effects include weight gain, muscle weakness, and fatigue.
TZDs are thought to work by binding to and activating the peroxisome proliferator-activated receptor gamma PPAR gamma. PPAR gamma is a protein that sits on the DNA in the nucleus of cells. When acted on by a TZD, it makes the cell create proteins that reduce blood sugar and improve insulin resistance. Two large clinical trials, DREAM and ADOPT, have demonstrated the efficacy of Avandia, but have also raised questions about the drug's safety.
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Keep all of your doctor's appointments so that your progress can be checked.
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