Generic Name: Generic actigall
What is Generic Actigall?
I was reading a lot about it and noticed that it talked about rapid weight loss being a cause for gallbladder disease and that doctor's can prescribe 2 different drugs to help the gallbladder process things better when someone is going to have a quick weight loss. The medicines were ursodiol and Orlistat.
Do you recommend we take this medicine. Maintaining a normal weight and avoiding rapid weight loss are the keys to reducing the risk of gallstones. Taking the medication ursodiol also called ursodeoxycholic acid, or Actigall during weight loss may reduce the risk for people who are very overweight and need to lose weight quickly.
This medication is ordinarily used to dissolve existing gallstones. Orlistat Xenicala drug for treating obesity, may protect against gallstone formation during weight loss.
The drug appears to reduce bile acids and other components involved in gallstone production. This study was designed to determine if a 6-month regimen of prophylactic ursodiol might prevent the development of gallstones. All patients had normal intraoperative gallbladder sonography. Transabdominal sonography was obtained at 2, 4, and 6 months following surgery, or until gallstone formation. Of 233 patients with at least one postoperative sonogram, 56 were randomized to placebo, 53 to 300 mg ursodiol, 61 to 600 mg ursodiol, and 63 to 1,200 mg ursodiol.
Estrogens, oral contraceptives, and clofibrate and perhaps other lipid-lowering drugs increase hepatic cholesterol secretion, and encourage cholesterol gallstone formation and hence may counteract the effectiveness of Actigall. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Ursodiol therapy has not been associated with liver damage. Lithocholic acid, a naturally occurring bile acid, is known to be a liver-toxic metabolite. This bile acid is formed in the gut from ursodiol less efficiently and in smaller amounts than that seen from chenodiol. Lithocholic acid is detoxified in the liver by sulfation and, although man appears to be an efficient sulfater, it is possible that some patients may have a congenital or acquired deficiency in sulfation, thereby predisposing them to lithocholateinduced liver damage.
Abnormalities in liver enzymes have not been associated with Actigall therapy and, in fact, Actigall has been shown to decrease liver enzyme levels in liver disease. However, patients given Actigall should have SGOT AST and SGPT ALT measured at the initiation of therapy and thereafter as indicated by the particular clinical circumstances.
It was not tumorigenic in mice. A 78-week rat study employing intrarectal instillation of lithocholic acid and tauro-deoxycholic acid, metabolites of ursodiol and chenodiol, has been conducted. These bile acids alone did not produce any tumors. A tumor-promoting effect of both metabolites was observed when they were co-administered with a carcinogenic agent.
Results of epidemiologic studies suggest that bile acids might be involved in the pathogenesis of human colon cancer in patients who had undergone a cholecystectomy, but direct evidence is lacking.
How should I take Generic Actigall?
However, check with your doctor if any of the following side effects continue or are bothersome:Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.
There is no additional information relating to proper use, precautions, or side effects for these uses. The latest news on hepatitis treatments, clinical trials, social issues and important breakthroughs. You'll find links to a comprehensive symptoms list, as well as various studies and discussions about Hepatitis C symptoms. Provides detailed information on how to analyze and interpret viral load numbers as well as a link to a convenient Viral Load Chart.
What they are and what they mean. Alternative methods of treatment due to side effects and dissatisfication with current medical treatments.
What should I avoid while taking Generic Actigall?
To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. Extracorporeal shock-wave lithotripsy and ursodiol versus ursodiol alone in the treatment of gallstones. Vanderpool D, Jones RC, O'Leary JP, Hamilton JK. Sackmann M, Pauletzki J, Sauerbruch T, Holl J, Schelling G, Paumgartner G. Gallstone recurrence after successful lithotripsy.
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Generic Actigall side effects
The two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug.
The rates at which the drug is delivered to the patient into their blood stream or otherwise absorbed are measured to ensure they are the same.
Because the same active ingredient is used the major concern is just that it delivers the common chemical s at the same rate so that they have the same effect. Q Contact Us Call Toll Free For More Information 1-866-940-3784 Login Place a New Order Place a Refill Order How to Order F. Q Contact Us Your cart is empty Checkout Login Login or Create new account Forgot password.
Actigall is a brand name for Ursodiol.
Common Generic Actigall ide effects may include:
Breast-feeding-It is not known whether ursodiol passes into the breast milk.
All Learning CentersCancerDiabetesHeart and CirculationLungs and AirwayMental and Behavioral HealthPregnancy and ChildbirthQuitting SmokingSubstance AbuseWeight ManagementWise Health ConsumerUPMC Patient EducationHealth Library Home PageCalculators and Assessment ToolsAnatomy NavigatorUrsodiol is a bile acid that decreases the amount of cholesterol produced by the liver and absorbed by the intestines.
Dietary administration of lithocholic acid to chickens is reported to cause hepatic adenomatous hyperplasia.
If the patient stops taking the drug the gallstones tend to recur if the condition that gave rise to their formation does not change.
This drug should be administered with food to facilitate its absorption. Your veterinarian may want to perform periodic ultrasound examinations of the liver to monitor the effect of therapy on gallstones.
The duration of administration depends on the condition being treated, response to the medication and the development of any adverse effects. Be certain to complete the prescription unless specifically directed by your veterinarian. Even if your pet feels better, the entire treatment plan should be completed to prevent relapse.
Where can I get more information?
This content reflects information from various individuals and organizations and may offer alternative or opposing points of view.
Dose should be rounded up, not down.