Generic Name: Abilify
What is Abilify?
Investigations: frequent -blood insulin increasedRenal and Urinary Disorders frequent - enuresisSkin and Subcutaneous Tissue Disorders: infrequent -hirsutismMost adverse reactions observed in the pooled database of 749 adult patients treated with ABILIFY injection, were also observed in the adult population treated with oral ABILIFY. Additional adverse reactions observed in the ABILIFY injection population are listed below. Table 25: Clinically Important Drug Interactions with ABILIFY: Concomitant Drug Name or Drug Class Clinical Rationale Clinical Recommendation Strong CYP3A4 Inhibitors e.
Strong CYP3A4 Inducers e. Antihypertensive Drugs Due to its alpha adrenergic antagonism, aripiprazole has the potential to enhance the effect of certain antihypertensive agents. ABILIFY has not been systematically studied in humans for its potential for abuse, tolerance, or physical dependence. Consequently, patients should be evaluated carefully for a history of drug abuse, and such patients should be observed closely for signs of ABILIFY misuse or abuse e.
In physical dependence studies in monkeys, withdrawal symptoms were observed upon abrupt cessation of dosing. You are encouraged to report negative side effects of prescription drugs to the FDA.
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222.
Canada residents can call a provincial poison control center. Symptoms of overdose may include: very fast heartbeat, loss of consciousness. Do not share this medication with others. Consult your doctor for more details. If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip themissed dose and resume your usual dosing schedule.
The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Subscribe to the WebMD Daily, and you'll get today's top health news and trending topics, and the latest and best information from WebMD.
Get organized and track baby's weekly development. Message BoardsConnect with people like you, and get expert guidance on living a healthy life. How to use AbilifyRead the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start taking aripiprazole and each time you get a refill.
How should I take Abilify?
The safety and efficacy of ABILIFY in the treatment of patients with psychosis associated with dementia have not been established. In placebo-controlled clinical studies two flexible dose and one fixed dose study of dementia-related psychosis, there was an increased incidence of cerebrovascular adverse events e. In the fixed-dose study, there was a statistically significant dose response relationship for cerebrovascular adverse events in patients treated with ABILIFY.
Suicide is a known risk of depression and certain other psychiatric disorders, and these disorders themselves are the strongest predictors of suicide. There has been a long-standing concern, however, that antidepressants may have a role in inducing worsening of depression and the emergence of suicidality in certain patients during the early phases of treatment. Pooled analyses of short-term, placebo-controlled trials of antidepressant drugs SSRIs and others showed that these drugs increase the risk of suicidal thinking and behavior suicidality in children, adolescents, and young adults ages 1824 with MDD and other psychiatric disorders.
What should I avoid while taking Abilify?
Gender No dosage adjustment is required for female patients as compared to male patients see section 5. Smoking status According to the metabolic pathway of aripiprazole no dosage adjustment is required for smokers see section 4.
Dose adjustments due to interactions When concomitant administration of potent CYP3A4 or CYP2D6 inhibitors with aripiprazole occurs, the aripiprazole dose should be reduced. Method of administration ABILIFY is for oral use. Hypersensitivity to the active substance or to any of the excipients listed in section 6.
During antipsychotic treatment, improvement in the patient's clinical condition may take several days to some weeks. Suicidality The occurrence of suicidal behaviour is inherent in psychotic illnesses and mood disorders and in some cases has been reported early after initiation or switch of antipsychotic treatment, including treatment with aripiprazole see section 4.
Abilify side effects
Have you gambled while on Abilify. Are you still taking Abilify. Abilify patients, including Abilify users who have incurred heavy gambling debts, have filed lawsuits against Abilify manufacturer Bristol-Myers Squibb. These suits allege links between Abilify use and damaging impulsive behavior, like uncontrollable gambling, binge eating, and hypersexual behavior, in users with no history of such conduct. The gambling addition can be so severe that patients go into extreme debt and even lose their homes.
In May 2016, the FDA issued a formal warning that the use of the antipsychotic drug aripiprazole Abilify, Abilify Maintena, Aristada, and also used in generic versions of the drug has been linked to compulsive urges which can lead to uncontrollable gambling, among other addictions. These rare but serious impulse-control problems reportedly stop when the medicine is discontinued or markedly reduced in dosage.
Abilify is a trademark of Otsuka Pharmaceutical Company and is used for informational and product identification purposes only.
Common Abilify ide effects may include:
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This syndrome may be irreversible.
It's specifically used to treat manic episodes in bipolar disorder, either alone or in combination with other anti-manic medications.
Patients treated with any antipsychotic medicinal products, including aripiprazole, should be observed for signs and symptoms of hyperglycaemia such as polydipsia, polyuria, polyphagia and weakness and patients with diabetes mellitus or with risk factors for diabetes mellitus should be monitored regularly for worsening of glucose control see section 4.
Common side effects of Abilify include insomnia, fatigue, and an inner sense of restlessness or need to move. This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information. This is not a complete list of Abilify side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Where can I get more information?
Aripiprazole undergoes minimal pre-systemic metabolism.